Peranan Muatan Lokal Materi Batik Tulis Lasem Sebagai Bentuk Pelestarian Budaya Lokal

Penelitian ini bertujuan mengkaji bagaimana pelaksanaan muatan lokal batik tulis Lasem pada tingkat sekolah dasar di Kecamatan Lasem sebagai bentuk pelestarian budaya lokal. Hasil penelitian ini menunjukkan pelaksanaan muatan lokal batik tulis Lasem pada kelas empat dan kelas lima. Masing-masing tingkatan mempunyai fokus kemampuan yang berbeda. Fokus kelas empat adalah pengenalan tentang batik, alat dan bahan membatik serta pengenalan ragam hias batik, sedang fokus kelas lima adalahpenjelasan sejarah batik tulis Lasem, tahapan membatik batik tulis Lasem, ragam hias batik tulis Lasem. Praktik pada kelas lima mulai dari ngethel, membuat pola, nglengkreng, nerusi, dan isen-isen. Pelaksanaan muatan lokal batik tulis Lasem kelas enam yaitu tentang sejarah dan ragam hias batik tulis Lasem melanjutkan tahapan dari kelas lima yang belum selesai. Muatan lokal tersebut berhasil menanamkan kepedulian dan kecintaan anak-anak pada batik tulis Lasem.The objective of this study is to examine the implementation of the local content batik Lasem at primary school in Lasem subdistrict as a form of local cultural preservation. The result of this study demonstrates that t local content batik Lasem is implemented in fourth, fifth and sixth grade. Each level has different focus. The focus of the fourth grade is the introduction of batik, batik tools and materials as well as the introduction of decorative batik. The focus of the fifth grade is on the history of Lasem batik, barik stages, decorative Lasem batik. The practice in fifth grade include ngethel, make patterns, nglengkreng, nerusi, and isen-isen. The implementation of the local content batik Lasem at sixth grade is about the history and decorative batik Lasem continuing the unfinished subjects in the fifth grade. Local content successfully instill kids’ awarness and love on batik Lasem

Pola Asuh Orang Tua Demokratis, Efikasi-diri Dan Kreativitas Remaja

Research for studies both simultaneous or partial correlations of democratic parenting and self-efficacy to creativity. Subject are 123 mid adolescence (60 boys and 63 girls), ages from 16 to 18 years old. Data taken from scales of C.O.R.E for creativity, P.A.O.D. for democratic parenting and ED-G for self-efficacy. Result of simultaneous test it R = 0,384, F = 10,349, p = 0,000 (p < 0,05). Democratic parenting and self-efficacy simultaneously and significant would have predicting creativity. R2 = 0,147 refer that 14,7% varians proportion on creativity would hava explained from democratic parenting and self-efficacy, othre for 85,3% could explained from other factors that not self-efficacy. Constant of 146,671 is score of creativity if no democratic parenting and self-efficacy. Result of partial test of democratic parenting t = 0,420, p = 0,675 (p > 0,05). Democratic parenting partially wasn't correlated with creativity. Result of partial test of self-efficacy t = 4,534, p = 0,000 (p < 0,05). Self-efficacy partially was significantly positive correlated with creativity. The findings are disscussed in terms of their implications for mid adolescent context

Frequency of etiologies of acute kidney injury in Faisalabad and surrounding districts

Background: To find out the causes of Acute Kidney Injury (AKI) in population.Methods: A total of 150 patients were enrolled from medical, surgical, gynecology and obstetrics units of Allied Hospital and Madinah Teaching Hospital, Faisalabad, Pakistan. History, physical examination and investigations were recorded on specially designed proforma. Patients were evaluated to find out the etiologies of AKI. All patients were subjected to urine analysis, complete blood count, blood biochemistry (urea, creatinine, electrolytes, uric acid, calcium and phosphorus) and ultrasound scan of the abdomen and pelvis. Renal biopsy, immunological assays, such as hepatitis B surface antigen, anti-hepatitis C virus antibody, complements level, antinuclear antibody, anti-double-stranded DNA, anti-neutrophil cytoplasmic antibody and anti-glomerular basement membrane antibody were performed in selected cases.Results: Male (36%) and female (64%). Pre-renal AKI was most common and was reported in 80 patients (53.33%). Intrinsic Renal azotemia in 56 patients (37.33%). Post renal azotemia in 14 patients (9.33%). Among 80 patients of prerenal AKI, hemorrhage in 45(56.25%), gastroenteritis in 16(20%), sepsis in 8(10%), cardiac diseases in 4(5%), hepatorenal syndrome in 3 (3.75%), peritonitis in 2 (2.50%) and burns in 2(2.50%) were the main causes of Pre-renal AKI. Among 56 patients of intrinsic renal AKI, 40(71.4%) had acute tubular necrosis (ATN), 12(21.4%) with multifactorial causes and 4(7.14%) were found to have glomerulonephritis. Among 14 patients of post renal AKI, 6(42.9%) were having calculi, 6(42.9%) were to have enlarged prostate and 2(4.3%) were having stricture urethra. In this study, contribution of obstetrical, medical and surgical etiologies were recorded as 40%, 36% and 20% respectively.Conclusions: In contrast to study reported from neighbouring country, this study shows rather increase in pregnancy related AKI

Green synthesis of methoxy-poly(ethylene glycol)- block-poly(L-lactide-co-glycolide) copolymer using zinc proline as a biocompatible initiator for irinotecan delivery to colon cancer in vivo

Poly(lactic-co-glycolic acid) (PLGA) is the most commonly described biocompatible copolymer used in biomedical applications. In this work, a green synthetic approach based on the biocompatible zinc proline complex, as an initiator for PLGA synthesis, is reported for the first time for the synthesis of methoxy-poly (ethylene glycol)-block-poly(L-lactic-co-glycolic acid) (mPEG–PLGA). mPEG–PLGA with controlled molecular weight and narrow polydispersity was synthesised. Its potential for delivery of irinotecan (Ir), a poorly water-soluble chemotherapeutic drug used for the treatment of colon and pancreatic cancer, was studied. Nanoparticles of controlled size (140–160 nm), surface charge (∼−10 mV), release properties and cytotoxicity against CT-26 (colon) and BxPC-3 (pancreatic) cancer cells, were prepared. Tumor accumulation was confirmed by optical imaging of fluorescently labelled nanoparticles. Unlike Tween® 80 coated NP-Ir, the Pluronic® F-127 coated NP-Ir exhibits significant tumor growth delay compared to untreated and blank formulation treated groups in the CT-26 subcutaneous tumor model, after 4 treatments of 30 mg irinotecan per kg dose. Overall, this proof-of-concept study demonstrates that the newly synthesized copolymer, via a green route, is proven to be nontoxic, requires fewer purification steps and has potential applications in drug deliver

Genome Wide Identification, Characterization and Evolutionary Analysis of T6SS in Burkholderia cenocepacia Strains

Pathogens of the Burkholderia genus are causing diseases in a diverse variety of hosts. After the discovery of T6SS, it was found to play a pivotal role in virulence and other pathogenicity factors in different pathogenic Burkholderia species. For this study, three strains of Burkholderia cenocepacia were selected from different ecological niches; J2315 from humans, MC0-3 from the rhizosphere of maize, and YG-3 from the Populus tree. The sequenced genomes were retrieved from PATRIC. It was found that B. cenocepacia J2315 and MC0-3 strains had only 1 cluster of T6SS in their genomes while the YG-3 strain had 3 clusters. The circular genomic map and phylogenetic tree suggested major differences in T6SS clusters 2 and 3 of the YG-3 strain from other clusters. From the results obtained in the study and reviewing the literature, it was concluded that all 3 strains harbor T6SS-1 type cluster that is involved in causing virulence in eukaryotic organisms and several bacterial species. This factor of causing virulence in the bacteria species might be helpful for B. cenocepacia strains J2315, MC0-3 and YG-3 in survival and niche adaptation

Analisis Penggunaan Limbah Resin Coated Sand sebagai Substitusi pada Cetakan Greensand Terhadap Karakteristik Pengecoran Logam Aluminium

Resin Coated Sand atau RCS  salah satu jenis cetakan yang digunakan untuk proses pengecoran logam dan menghasilkan limbah yang mengandung resin. Sebagian besar limbah RCS  masih dapat  didaur ulang, karena masih mengandung pasir silika dan berukuran lebih kecil dibandingkan pasir silika untuk cetakan greensand. Cetakan greensand terdiri dari pasir silika dengan pengikat merupakan cetakan pasir yang sering digunakan pada industri pengecoran logam. Penelitian ini bertujuan untuk mengetahui bagaimana pengaruh penambahan limbah pasir RCS pada cetakan greensand terhadap karakteristik kekerasan dan struktur mikro pada peleburan ulang aluminium-silikon. Penelitian ini dilaksanakan untuk mendapatkan data pada komposisi limbah cetakan pasir RCS dengan presentase 0%, 20%, dan 40% terhadap pasir baru grendsand, sedangkan material logam aluminium yang digunakan pada penelitian ini mengunakan limbah sepatu rem tromol sepeda motor. Hasil pengecoran logam didapat spesimen logam aluminium yang diuji kekerasan dan metalografi. Pada penambahan RCS 20% menunjukkan nilai kekerasan yang cenderung sama pada penambahan 0%, namun nilai kekerasan akan naik 2,4 kali pada penambahan RCS 40%. Berdasarkan pengujian metalografi penambahan RCS 40% menunjukkan struktur fasa Si yang cenderung lebih meluas dibandingkan pada penambahan 0% dan 20%

SARS-CoV-2 Antibody Seroprevalence in Jakarta, Indonesia

The SARS-CoV-2 transmission dynamics in low- and middle-income countries remain poorly understood. This study aimed to estimate the SARS-CoV-2 antibodies seroprevalence in Jakarta, Indonesia, and to increase knowledge of SARS-CoV-2 transmission in urban settings. A population-based serosurvey among individuals aged one year or older was conducted in Jakarta. Employing a multistage sampling design, samples were stratified by district, slum, and non-slum residency, sex, and age group. Blood samples were tested for IgG against three different SARS-CoV-2 antigens. Seroprevalence was estimated after applying sample weights and adjusting for cluster characteristics. In March 2021, this study collected 4,919 respondents. The weighted estimate of seroprevalence was 44.5% (95% CI = 42.5-46.5). Seroprevalence was highest among adults aged 30-49 years, with higher seroprevalence in women and the overweight/obese group. Respondents residing in slum areas were 1.3-fold more likely to be seropositive than non-slum residents. It was estimated that4,717,000 of Jakarta's 10.6 million residents had prior SARS-CoV-2 infection. This suggests that approximately 10 infections were undiagnosed/underreported for every reported case. About one year after the first COVID-19 case was confirmed, close to half of Jakarta's residents have been infected by SARS-CoV-2