The map of interactions between ligands and TLR4.

A) ht-Map2191 and B) ht-FAP-P. Green dotted lines represent hydrogen bonds.</p

Fig 3 -

Ramachandran plot of A) ht-MAP2191 and B) ht-FAP-P.</p

The amino acid residue content of conformational B-Cell epitopes predicted by the ElliPro server.

Common residues detected by both Ellipro and Discotope servers are marked in blue.</p

LBL epitopes of constructs predicted by ABCPred server.

Common residues detected by both ABCPred and BepiPred servers are marked in blue.</p

Amino acids involved in hydrogen-bonding interactions.

Amino acids involved in hydrogen-bonding interactions.</p

S1 Fig -

(DOCX)</p

Fig 6 -

Docked complexes of A) ht-Map2191-TLR4 and B) ht-FAP-P-TLR4. The receptor is shown in blue, while ligands are shown in red.</p

Fig 1 -

Kyte and Doolittle Hydrophobicity plot derived from the MAP2191 (A) and FAP-P (B) conserved amino acid sequences. The hydrophilic residues are below the blue line, and the hydrophobic residues are shown above the blue line.</p

ht-MAP-2191 CTL epitopes with highest score.

ht-MAP-2191 CTL epitopes with highest score.</p

ht-FAP-P CTL epitopes with highest score.

ht-FAP-P CTL epitopes with highest score.</p