2 research outputs found
Media coverage of violence against women in India: a systematic study of a high profile rape case
High Yielding Preparation of Dicarba-<i>closo</i>-dodecaboranes Using a Silver(I) Mediated Dehydrogenative Alkyne-Insertion Reaction
The synthesis of 1,2-dicarba-<i>closo</i>-dodecaboranes (<i>ortho</i>-carboranes)
is often low yielding which is a critical issue given the increasing
use of boron clusters in material science and medicinal chemistry.
To address this barrier, a series of Cu, Ag, and Au salts were screened
to identify compounds that would enhance the yields of <i>ortho</i>-caboranes produced when treating alkynes with B<sub>10</sub>H<sub>12</sub>(CH<sub>3</sub>CN)<sub>2</sub>. Using a variety of functionalized
ligands including mono- and polyfunctional internal and terminal alkynes,
significant increases in yield were observed when AgNO<sub>3</sub> was used in catalytic amounts. AgNO<sub>3</sub> appears to prevent
unwanted reduction/hydroboration of the alkyne prior to carborane
formation, and the process is compatible with aryl, halo, hydroxy,
nitrile, carbamate, and carbonyl functionalized alkynes