Amino acid conservation of amino acids of ASB10 in different species.

<p>Mutated amino acids conserved in humans and other species are shown in blue color.</p

Pedigrees of consanguineous Pakistani glaucoma families, with a probable autosomal dominant inheritance pattern.

<p>Segregation analysis of three nonsynonmous variants: (<b>1A)</b> represents segregation of p.Arg49Cys, <b>(1B)</b> segregation of p.Arg237Gly change, <b>(1C)</b> shows p.Arg453Cys variant segregation, Variant allele is indicated with an “M1(p.Arg49Cys), M2(p.Arg237Gly) and M3(p.Arg453Cys)”, and the wildtype allele indicated with “WT” for the three variations. This demonstrates that the variants do not segregate with the disease in the respective families. The proband is indicated with an arrow.</p

Results of logistic regression analysis for Genotype and allele frequency of SNPs rs11720822 in <i>PDIA5</i> and rs2754511 in <i>BIRC6</i> in POAG, PCAG and PEXG patients and control individuals.

a<p>Age and gender adjusted OR and (95%CI) from multivariate logistic regression analysis; p^bBonferoni corrected p values; ^cOR and (95%CI) from univariate logistic regression analysis; Est., estimates</p