7 research outputs found

    Mean z-score matrices for the control and PNE groups.

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    <p>Each figure shows a 116×116 square matrix in which the x- and y-axes correspond to AAL regions. Each entry indicates the mean z-score representing functional connectivity between each pair of regions in the brain.</p

    DataSheet1_Lable-free aptamer portable colorimetric smartphone for gliadin detection in food.pdf

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    For individuals with celiac disease (CD), the current clinical therapy option available is a lifelong gluten-free diet. Therefore, it is essential to swiftly and efficiently detect gluten in foods. A colorimetric sensor has been developed, which operates by regulating the aggregation and dispersion state of AuNPs induced by high concentration NaCl through the specific binding of gliadin and aptamer, thereby achieving rapid detection of gliadin in flour. It is found that the sensor exhibits good linearity in the concentration range of 0.67–10 μM and the LOD (3σ/S) is 12 nM. And it can accurately distinguish various types of free-gliadin samples, with a spiked recovery rate of 85%–122.3%. To make the detection process more convenient, the colorimetric results of the biosensor were translated into RGB color-gamut parameters by a smartphone color-picking program for further analysis. Gliadin can still be accurately quantified with the established smartphone platform, and a correlation coefficient of 0.988 was found. The proposed portable smartphone aptamer colorimetric sensing device has achieved satisfactory results in the rapid detection of gliadin in food.</p

    Likelihood ratio tests of branch-site models on <i>C3</i> genes.

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    <p>Note: np number of parameters, ln<i>L</i> ln[likelihood] value, 2Δ(ln<i>L</i>) twice the difference of ln[likelihood] between the two models compared, vert, mam, OP, and Acan the ancestor branches of the vertebrates, mammals, ostariophysian together with protacanthopterygian fishes, and acanthopterygians fishes, respectively, examined in present study, seabass2 the seabass <i>C3-2</i>, stickleback5 the three-spined stickleback <i>C3-5</i>.The <i>P</i>-values<0.01 are shown in boldface. The human <i>C3</i> sequence was used as reference to mark the positions of the positive sites in all cases. Sites with the <i>P</i>-values<0.05 are shown and those with <i>P</i>-values<0.01 are in boldface.</p

    The putative gene tree for <i>C3</i> reconstructed by Bayesian approach with no constraints on the topology.

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    <p>The Darwin selection pressures were detected by the branch-site models in the ancestral lineages to vertebrates (in green), mammals (in red) and ostariophysian together with protacanthopterygian (Ost+Pro) fishes (in blue). The positive selected sites with posterior probabilities larger than 0.95 (PP>0.99 in bold) were showed on the corresponding lineages. The synonymous substitution (<i>d</i><sub>N</sub>), non-synonymous substitution (<i>d</i><sub>S</sub>) of nucleotides and the ratio of <i>d</i><sub>N/</sub><i>d</i><sub>S</sub> of these ancestral lineages were showed. The sequences of mammalian (red) and fish <i>C3</i> (blue) were then tested by site-model tests in next analysis, respectively.</p

    Sliding window analysis of variation in omega value along fish and mammalian <i>C3</i> genes.

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    <p>It was set to be 90 bp for the window size and 36 bp for the step size. Beneath the plot is a schematic of the <i>C3</i> gene, which illustrates the distribution of the characteristic domains.</p
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