1,077 research outputs found
Nonclassicality of photon-added squeezed vacuum and its decoherence in thermal environment
We study the nonclassicality of photon-added squeezed vacuum (PASV) and its
decoherence in thermal environment in terms of the sub-Poissonian statistics
and the negativity of Wigner function (WF). By converting the PASV to a
squeezed Hermite polynomial excitation state, we derive a compact expression
for the normalization factor of m-PASV, which is an m-order Legendre polynomial
of squeezing parameter r. We also derive the explicit expression of WF of
m-PASV and find the negative region of WF in phase space. We show that there is
an upper bound value of r for this state to exhibit sub-Poissonian statistics
increasing as m increases. Then we derive the explicit analytical expression of
time evolution of WF of m-PASV in the thermal channel and discuss the loss of
nonclassicality using the negativity of WF. The threshold value of decay time
is presented for the single PASV.Comment: 14 pages and 7 figure
Observational constraints on Cosmic Reionization
Recent observations have set the first constraints on the epoch of
reionization (EoR), corresponding to the formation epoch of the first luminous
objects. Studies of Gunn-Peterson (GP) absorption, and related phenomena,
suggest a qualitative change in the state of the intergalactic medium (IGM) at
, indicating a rapid increase in the neutral fraction of the IGM,
from , perhaps up to
0.1, at . Conversely, transmission spikes in the GP trough, and the
evolution of the \lya galaxy luminosity function indicate at
, while the large scale polarization of the cosmic microwave
background (CMB) implies a significant ionization fraction extending to higher
redshifts, . The results suggest that reionization is less an
event than a process, with the process beginning as early as , and
with the 'percolation', or 'overlap' phase ending at . The data are
consistent with low luminosity star forming galaxies as being the dominant
sources of reionizing photons. Low frequency radio telescopes currently under
construction should be able to make the first direct measurements of HI 21cm
emission from the neutral IGM during the EoR, and upcoming measurements of
secondary CMB temperature anisotropy will provide fine details of the dynamics
of the reionized IGM.Comment: to appear in ARAA 2006, vol 44, page 415-462; latex. 84 pages. 15 fi
A rare presentation of atypical demyelination: tumefactive multiple sclerosis causing Gerstmann's syndrome
r. KS has been supported by a Higher Education Funding Council for
England (HEFCE) Clinical Senior Lectureshi
Hsp20 Functions as a Novel Cardiokine in Promoting Angiogenesis via Activation of VEGFR2
Heat shock proteins (Hsps) are well appreciated as intrinsic protectors of cardiomyocytes against numerous stresses. Recent studies have indicated that Hsp20 (HspB6), a small heat shock protein, was increased in blood from cardiomyopathic hamsters. However, the exact source of the increased circulating Hsp20 and its potential role remain obscure. In this study, we observed that the circulating Hsp20 was increased in a transgenic mouse model with cardiac-specific overexpression of Hsp20, compared with wild-type mice, suggesting its origin from cardiomyocytes. Consistently, culture media harvested from Hsp20-overexpressing cardiomyocytes by Ad.Hsp20 infection contained an increased amount of Hsp20, compared to control media. Furthermore, we identified that Hsp20 was secreted through exosomes, independent of the endoplasmic reticulum-Golgi pathway. To investigate whether extracellular Hsp20 promotes angiogenesis, we treated human umbilical vein endothelial cells (HUVECs) with recombinant human Hsp20 protein, and observed that Hsp20 dose-dependently promoted HUVEC proliferation, migration and tube formation. Moreover, a protein binding assay and immunostaining revealed an interaction between Hsp20 and VEGFR2. Accordingly, stimulatory effects of Hsp20 on HUVECs were blocked by a VEGFR2 neutralizing antibody and CBO-P11 (a VEGFR inhibitor). These in vitro data are consistent with the in vivo findings that capillary density was significantly enhanced in Hsp20-overexpressing hearts, compared to non-transgenic hearts. Collectively, our findings demonstrate that Hsp20 serves as a novel cardiokine in regulating myocardial angiogenesis through activation of the VEGFR signaling cascade
Do oral aluminium phosphate binders cause accumulation of aluminium to toxic levels?
<p>Abstract</p> <p>Background</p> <p>Aluminium (Al) toxicity was frequent in the 1980s in patients ingesting Al containing phosphate binders (Alucaps) whilst having HD using water potentially contaminated with Al. The aim of this study was to determine the risk of Al toxicity in HD patients receiving Alucaps but never exposed to contaminated dialysate water.</p> <p>Methods</p> <p>HD patients only treated with Reverse Osmosis(RO) treated dialysis water with either current or past exposure to Alucaps were given standardised DFO tests. Post-DFO serum Al level > 3.0 μmol/L was defined to indicate toxic loads based on previous bone biopsy studies.</p> <p>Results</p> <p>39 patients (34 anuric) were studied. Mean dose of Alucap was 3.5 capsules/d over 23.0 months. Pre-DFO Al levels were > 1.0 μmol/L in only 2 patients and none were > 3.0 μmol/L. No patients had a post DFO Al levels > 3.0 μmol/L. There were no correlations between the serum Al concentrations (pre-, post- or the incremental rise after DFO administration) and the total amount of Al ingested.</p> <p>No patients had unexplained EPO resistance or biochemical evidence of adynamic bone.</p> <p>Conclusions</p> <p>Although this is a small study, oral aluminium exposure was considerable. Yet no patients undergoing HD with RO treated water had evidence of Al toxicity despite doses equivalent to 3.5 capsules of Alucap for 2 years. The relationship between the DFO-Al results and the total amount of Al ingested was weak (R<sup>2 </sup>= 0.07) and not statistically significant. In an era of financial prudence, and in view of the recognised risk of excess calcium loading in dialysis patients, perhaps we should re-evaluate the risk of using Al-based phosphate binders in HD patients who remain uric.</p
Impact of antenna correlation on the performance of partial relay selection
Antenna correlation is generally viewed as an obstacle to realize the desired performance of a wireless system. In this article, we investigate the performance of partial relay selection in the presence of antenna correlation. We consider both channel state information (csi)-assisted and fixed gain amplify-and-forward (AF) relay schemes. The source and the destination are equipped with multiple antennas communicating via the best first hop signal-to-noise ratio (SNR) relay. We derived the closed form expression for outage probability, average symbol error rate (SER) for both schemes. Further, an exact expression is derived for the ergodic capacity in the csi-assisted relay case and an approximated expression is considered for the fixed gain case. Moreover, we provide simple asymptotic results and show that the diversity order of the system remains unchanged with the effect of antenna correlation for both types of relay schemes
Bridging ultrahigh-Q devices and photonic circuits
Optical microresonators are essential to a broad range of technologies and scientific disciplines. However, many of their applications rely on discrete devices to attain challenging combinations of ultra-low-loss performance (ultrahigh Q) and resonator design requirements. This prevents access to scalable fabrication methods for photonic integration and lithographic feature control. Indeed, finding a microfabrication bridge that connects ultrahigh-Q device functions with photonic circuits is a priority of the microcavity field. Here, an integrated resonator having a record Q factor over 200 million is presented. Its ultra-low-loss and flexible cavity design brings performance to integrated systems that has been the exclusive domain of discrete silica and crystalline microcavity devices. Two distinctly different devices are demonstrated: soliton sources with electronic repetition rates and high-coherence/low-threshold Brillouin lasers. This multi-device capability and performance from a single integrated cavity platform represents a critical advance for future photonic circuits and systems
The Classification of T Dwarfs
We discuss methods for classifying T dwarfs based on spectral morphological
features and indices. T dwarfs are brown dwarfs which exhibit methane
absorption bands at 1.6 and 2.2 . Spectra at red optical (6300--10100
{\AA}) and near-infrared (1--2.5 ) wavelengths are presented, and
differences between objects are noted and discussed. Spectral indices useful
for classification schemes are presented. We conclude that near-infrared
spectral classification is generally preferable for these cool objects, with
data sufficient to resolve the 1.17 and 1.25 K I doublets lines being
most valuable. Spectral features sensitive to gravity are discussed, with the
strength of the K-band peak used as an example. Such features may be used to
derive a two-dimensional scheme based on temperature and mass, in analogy to
the MK temperature and luminosity classes.Comment: 15 pages, 6 figures, conference proceedings for IAU Ultracool Dwarf
Stars session, ed. I. Steele & H. Jone
Effect of power and rate adaptation on the spectral efficiency of MQAM/OFDM system under very fast fading channels
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