Comparing the Presence of Researchers of Medical Universities of Western Provinces of Iran on ResearchGate and Scopus

The aim of the present study was to compare the presence of researchers of Medical Universities of Western Provinces of Iran (i.e., Kurdistan, Hamadan, Kermanshah, and Ilam) on ResearchGate and Scopus using altmetric approach. This research also aimed to identify the significant difference between the Scopus indicators and the altmetric indicators of ResearchGate. The statistical population of this research consists of the researchers from University of Medical Sciences in Kurdistan, Hamadan, Kermanshah and Ilam with indexed documents in Scopus and affiliated with ResearchGate that were compared and reviewed by the author's work on ResearchGate. According to Scopus, Kurdistan University of Medical Sciences had the highest average number of documents, Hamadan University of Medical Sciences has the highest average h-index, and Kermanshah University of Medical Sciences had the highest average citation count. Based on the number of publications, Ilam University of Medical Sciences had the highest average, based on the ResearchGate Score (RG Score), Kurdistan University of Medical Sciences had the highest score and based on the following and followers indicators, Kermanshah University of Medical Sciences received the highest score. Increasing the number of documents uploaded on ResearchGate will increase the citations in Scopus and, consequently, the h-index will increase

Comparing the Presence of Researchers of Medical Universities of Western Provinces of Iran on ResearchGate and Scopus

The aim of the present study was to compare the presence of researchers of Medical Universities of Western Provinces of Iran (i.e., Kurdistan, Hamadan, Kermanshah, and Ilam) on ResearchGate and Scopus using altmetric approach. This research also aimed to identify the significant difference between the Scopus indicators and the altmetric indicators of ResearchGate. The statistical population of this research consists of the researchers from University of Medical Sciences in Kurdistan, Hamadan, Kermanshah and Ilam with indexed documents in Scopus and affiliated with ResearchGate that were compared and reviewed by the author's work on ResearchGate. According to Scopus, Kurdistan University of Medical Sciences had the highest average number of documents, Hamadan University of Medical Sciences has the highest average h-index, and Kermanshah University of Medical Sciences had the highest average citation count. Based on the number of publications, Ilam University of Medical Sciences had the highest average, based on the ResearchGate Score (RG Score), Kurdistan University of Medical Sciences had the highest score and based on the following and followers indicators, Kermanshah University of Medical Sciences received the highest score. Increasing the number of documents uploaded on ResearchGate will increase the citations in Scopus and, consequently, the h-index will increase

Labor induction with randomized comparison of cervical, oral and intravaginal misoprostol

Background: This study attempts to evaluate the safety and efectiveness of 50μgm intracervical misoprostol in comparison with intravaginal and sublingual for the induction of labor at term pregnant women. Methods: This study is designed as a parallel clinical trial study. Three hundred and ffteen term pregnancies requiring induction of labor were treated with the maximum used misoprostol intracervical, sublingual, and vaginal doses. Participants were randomly allocated into three groups of 105. The dose was repeated every 4h until adequate uterine contraction and Bishop Score were achieved. The duration of induction to births, time to the active phase, the rate of births, and the need for caesarean section were compared in three groups. Additionally, labor course and side efects were recorded and analyzed. Data were analyzed using SPSS software. A signifcance level of p< 0.05 was considered for statistical analyses. Findings: Labor was successfully induced in all cases most (63%) of which required a single dose of misoprostol. Ninety-three (93.0%, p< 0.05) cervical participants proceeded to vaginal births. This fgure was also the same in the vaginal and sublingual group of 83 cases (83.0%). The other 41 cases received caesarean section with more indications of failure to progress and meconium-stained liquor. The results indicated that 278 (92.7%) births were achieved in less than 10h. Time from start of medication to the active phase of labor and childbirth was 3.01±0.86 and 6.1±1.3h in the Cervical group, 4.2±0.66 and 8.4±0.92h in the sublingual group, and 5.06±1.1 and 9.2±1.5h in the vaginal group respectively (p<0.001). The Caesarean rate was lower in the cervical group than in the two other groups (p=0.05). No signifcant diferences were observed between the study groups in terms of Apgar score and meconium-stained amniotic fuid. Furthermore, no maternal and neonatal complications were observed. Conclusion: In addition to the sublingual and intravaginal routes of administration, intracervical misoprostol at a single dose of 50μgm appears to be an efective method for induction of labor in women with an unfavorable cervix. Like all medical interventions, a discussion of the risks, benefts, and alternatives to induction of labor with this medication in each woman should be undertaken before treatment. Trial registration: This clinical study was approved by the Iranian Registry of Clinical Trials with IRCT ID: IRCT201904 15043278N1. Registration date was on May 13, 2019 and May 27, 2019 respectively (http://www.irct.ir). Keywords: Misoprostol, Labor induced, Term birt

Labor induction with randomized comparison of cervical, oral and intravaginal misoprostol

Background: This study attempts to evaluate the safety and effectiveness of 50μgm intracervical misoprostol in comparison with intravaginal and sublingual for the induction of labor at term pregnant women. Methods: This study is designed as a parallel clinical trial study. Three hundred and fifteen term pregnancies requiring induction of labor were treated with the maximum used misoprostol intracervical, sublingual, and vaginal doses. Participants were randomly allocated into three groups of 105. The dose was repeated every 4 h until adequate uterine contraction and Bishop Score were achieved. The duration of induction to births, time to the active phase, the rate of births, and the need for caesarean section were compared in three groups. Additionally, labor course and side effects were recorded and analyzed. Data were analyzed using SPSS software. A significance level of p < 0.05 was considered for statistical analyses. Findings: Labor was successfully induced in all cases most (63%) of which required a single dose of misoprostol. Ninety-three (93.0%, p < 0.05) cervical participants proceeded to vaginal births. This figure was also the same in the vaginal and sublingual group of 83 cases (83.0%). The other 41 cases received caesarean section with more indications of failure to progress and meconium-stained liquor. The results indicated that 278 (92.7%) births were achieved in less than 10 h. Time from start of medication to the active phase of labor and childbirth was 3.01 پ} 0.86 and 6.1 1.3 h in the Cervical group, 4.2 پ} 0.66 and 8.4 0.92 h in the sublingual group, and 5.06 1.1 and 9.2 1.5 h in the vaginal group respectively (p < 0.001). The Caesarean rate was lower in the cervical group than in the two other groups (p = 0.05). No significant differences were observed between the study groups in terms of Apgar score and meconium- stained amniotic fluid. Furthermore, no maternal and neonatal complications were observed. Conclusion: In addition to the sublingual and intravaginal routes of administration, intracervical misoprostol at a single dose of 50μgm appears to be an effective method for induction of labor in women with an unfavorable cervix. Like all medical interventions, a discussion of the risks, benefits, and alternatives to induction of labor with this medication in each woman should be undertaken before treatment. Trial registration: This clinical study was approved by the Iranian Registry of Clinical Trials with IRCT ID: IRCT2 01904 15043 278N1. Registration date was on May 13, 2019 and May 27, 2019 respectively (http:// www. irct. ir). Keywords: Misoprostol, Labor induced, Term birt

Evaluation the cytotoxic effect of cytotoxin-producing Klebsiella oxytoca isolates on the HEp-2 cell line by MTT assay

Background: The cytotoxic effects on epithelial cells of the human are not observed in other strains of Klebsiella spp and are only observed in K. oxytoca strains. MTT assay was used to evaluate cytotoxic activity. In this study, colorimetric method was used to evaluate the cytotoxic effect of cytotoxin-producing isolates on Hep-2 cell line and determines the percentage of surviving cells. Materials and methods: In this study, we collected a total of 75 K. oxytoca strains isolate and we detected the production of toxins and their cytotoxic effects on HEp-2 cells. Colorimetric method such as MTT assay was used to evaluate the cytotoxic effect of cytotoxin-producing isolates on Hep-2 cell line and determines the percentage of surviving cells. Results: Nine isolates had cytotoxic effects on HEp-2 cells. The results of MTT assay showed that the isolated strains were different from the control stain in terms of toxinogenicity and cytotoxic effects on HEp-2 cells at the studied dilutions (1:3, 1:6, 1:12, 1:24, 1:48, and 1:96). Conclusions: In the current study, Percentage of Hep-2 surviving cells exposed to 1:3, 1:6, 1:12, 1:24, 1:48, and 1:96 supernatant dilutions of cytotoxin-producing Klebsiella oxytoca isolates was different

Identification of Klebsiella pneumoniae Carbapenemase-producing Klebsiella oxytoca in Clinical Isolates in Tehran Hospitals, Iran by Chromogenic Medium and Molecular Methods

Objectives: Production of carbapenemase, especially Klebsiella pneumoniae carbapenemases (KPC), is one of the antibiotic resistance mechanisms of Enterobacteriaceae such as Klebsiella oxytoca. This study aimed to investigate and identify KPC-producing K. oxytoca isolates using molecular and phenotypic methods. Methods: A total of 75 isolates of K. oxytoca were isolated from various clinical samples, and were verified as K. oxytoca after performing standard microbiological tests and using a polymerase chain reaction (PCR) method. An antibiotic susceptibility test was performed using a disc diffusion method according to the Clinical and Laboratory Standards Institute guidelines. CHROMagar KPC chromogenic culture media was used to examine and confirm the production of the carbapenemase enzyme in K. oxytoca isolates; in addition, PCR was used to evaluate the presence of blaKPC gene in K. oxytoca strains. Results: Of a total of 75 K. oxytoca isolates, one multidrug resistant strain was isolated from the urine of a hospitalized woman. This strain was examined to assess its ability to produce carbapenemase enzyme; it produced a colony with a blue metallic color on the CHROMagar KPC chromogenic culture media. In addition, the blaKPC gene was confirmed by PCR. After sequencing, it was confirmed and deposited in GenBank. Conclusion: To date, many cases of KPC-producing Enterobacteriaceae, in particular K. pneumoniae, have been reported in different countries; there are also some reports on the identification of KPC-producing K. oxytoca. Therefore

Identification of cytotoxin-producing Klebsiella oxytoca strains isolated from clinical samples with cell culture assays

BACKGROUND: Klebsiella oxytoca is an opportunistic pathogen which damages intestinal epithelium through producing cytotoxin tilivalline. This toxin plays a role in the pathogenesis of bacteria and is the main virulence factor which leads to antibiotic-associated hemorrhagic colitis progress. MATERIALS AND METHODS: In this study, we collected a total of 75 K. oxytoca strains isolated from the stool, urine, blood, wounds, and sputum and evaluated them in terms of the production of toxins; we detected their cytotoxic effects on HEp-2 cells. RESULTS: Of all the isolates, five K. oxytoca strains isolated from the stool cultures, two strains isolated from the blood cultures, one strains isolated from the wound cultures, and one strains isolated from the urine cultures had cytotoxic effects on HEp-2 cells. The strains isolated from sputum cultures had no cytotoxic effects on HEp-2 cells. CONCLUSIONS: In the current study, the majority of strains isolated from the stool of the patients included cytopathic effects on HEp-2 cells. Copyright © 2017 Elsevier Ltd. All rights reserved

Bibliometric Analysis of the Top Ten Percent Iranian Medical Researchers Based on the I10-index and the H-index in Web of Science

The i10-index is one of the newest scientometric indicators used to evaluate researchers in any field of science. The present study analyzes the top ten percent of Iranian medical researchers using the i10-index in the Web of Science database. The present study is descriptive-analytical research conducted using a scientometric approach. The research population includes the top ten percent of Iranian medical researchers whose publications were indexed in the Web of Science database between 2011 and 2020. Descriptive and inferential statistics and i10-index were used to analyze the data using the HistCite and the BibExcel software. Then, the results were sorted in the Excel software. Finally, the h-index and the number of citations of all researchers were compared with their i10-index. The findings show that in medical sciences, Iran ranked 23rd in the world, sixth in Asia, and first in the Middle East in Web of Science in the period 2011-2020, and the growth of scientific publications shows an upward trend. Moreover, there is a direct and positive relationship between the h-index and the i10-index of the top ten percent of medical researchers. This is confirmed with a correlation of 0.645. Also, a correlation of 0.269 shows a direct and positive relationship between the number of citations and the i10-index of the top ten percent of medical researchers. The results show that there is a positive and direct relationship between the h-index and the number of citations of the top ten percent of Iranian medical researchers with their i10-index

Liquid-liquid Extraction of Palladium (II) in Acidic Chloride Solutions Using Tri-n-octylamine

The extraction of palladium in hydrochloric acid solution (200 ppm) using tri-n-octylamine (TOA) as extractant were performed in four different solvents (toluene, xylene, crosin and 1, 2-dichloroethane) via liquid-liquid method. The effect of extraction time and material concentration investigated for Pd (Ⅱ) extraction. The maximum extraction for palladium achieved with 1% TOA in 0.05 M HCl medium in 15 min with toluene. After the extraction, the Pd (Ⅱ)-loaded organic phase was stripped with different stripping agents. Results showed that Pd (Ⅱ) stripping is better achieved by 8 M ammonia solution. The percentage stripping of palladium (Ⅱ) was 100% in this condition

The effects of psychological risk factors at work on cognitive failures through the accident proneness

Background Various agents such as psychosocial items and accident proneness can affect cognitive failures through different paths. The probable paths are the direct effects of workplace psychosocial items on cognitive failures and their indirect effects on cognitive failures through the mediator variable of accident proneness, which has not yet been studied by others. Thus, the present study aimed to investigate these paths. Methods This cross-sectional study was conducted on 164 male employees of Karoon Sugar Company in 2018. The participants were asked to complete a background and demographic questionnaire, Broadbent cognitive failures scale, accident proneness questionnaire, and Copenhagen psychosocial questionnaire. Obtained data were analyzed and modeled using the statistical descriptive method, ANOVA, independent t-test, Pearson correlation test, and path analysis in the SPSS and AMOS software. Results The results of the path analysis showed that, not only, some psychosocial risk items had a significant direct effect on cognitive failures, but also, they could affect cognitive failures through the accident proneness, indirectly. Work-family conflict and social support from supervisors by coefficients of 0.188 and - 0.187 had the highest direct effects, respectively. The highest indirect effects belonged to justice and respect, and work-family conflict by coefficients of - 0.220 and 0.199, respectively. The highest total effects were also related to the work-family conflict and justice and respect by coefficients of 0.387 and - 0.381, respectively. Conclusions In total, our results showed that some psychological items could, directly and indirectly, increase cognitive failure through accident proneness