8,403 research outputs found
Miniature vibration isolator Patent
Miniature vibration isolator utilizing elastic tubing materia
Canister closing device Patent
Design and characteristics of device for closing canisters under high vacuum condition
Capacity of different cell types to stimulate cytotoxic T lymphocyte precursor cells in the presence of interleukin 2
Plastic-adherent cells enriched for dendritic cells (AC) were found to be among the most potent stimulator cells for the activation of cytotoxic T lymphocytes (CTL) in vitro in the presence of interleukin 2 (IL 2) and a constant second set of allogeneic stimulator cells. Concanavalin A-activated nylon wool-nonadherent spleen cells ( CNWT ), concanavalin A-activated unfractionated spleen cells ( Cspl ), and some variants of the ESb T lymphoma line were equally effective as stimulator cells, however, and provoked a substantial cytotoxic response at concentrations of 10(4) cells per culture or less. In contrast, nonactivated nylon wool-nonadherent spleen cells ( NWT ) or unfractionated spleen cells (Spl) and cells of the P815 mastocytoma, the Meth A fibrosarcoma, and the T cell lymphomas Ly 5178 Eb and ESb did not stimulate cytotoxic responses at these cell concentrations. The strong stimulatory potential of the Cspl preparation was reduced by treatment with anti-Thy-1 antibody plus complement, whereas the stimulatory activity of the AC preparation was resistant to this treatment. All cell types tested expressed class I major histocompatibility antigens. Nonactivated NWT cells, in contrast to the CNWT preparation, showed no detectable staining with anti-I-E or anti-I-A antibodies and also a slightly weaker staining with class I antisera. Experiments with the tumor cell lines revealed, however, that there was no strict correlation between stimulatory potential and density of class I alloantigens or the expression of I-E determinants. Experiments on primary cytotoxic responses in vivo gave similar results. Experiments in cultures with a single set of stimulator cells and I region-compatible responder cells indicated that AC and Cspl or CNWT also have a markedly stronger capacity than NWT to induce IL 2-dependent DNA synthesis
Chromosome mapping: radiation hybrid data and stochastic spin models
This work approaches human chromosome mapping by developing algorithms for
ordering markers associated with radiation hybrid data. Motivated by recent
work of Boehnke et al. [1], we formulate the ordering problem by developing
stochastic spin models to search for minimum-break marker configurations. As a
particular application, the methods developed are applied to 14 human
chromosome-21 markers tested by Cox et al. [2]. The methods generate
configurations consistent with the best found by others. Additionally, we find
that the set of low-lying configurations is described by a Markov-like ordering
probability distribution. The distribution displays cluster correlations
reflecting closely linked loci.Comment: 26 Pages, uuencoded LaTex, Submitted to Phys. Rev. E,
[email protected], [email protected]
Phenomenological Study of Strong Decays of Heavy Hadrons in Heavy Quark Effective Theory
The application of the tensor formalism of the heavy quark effective theory
(HQET) at leading order to strong decays of heavy hadrons is presented.
Comparisons between experimental and theoretical predictions of ratios of decay
rates for B mesons, D mesons and kaons are given. The application of HQET to
strange mesons presents some encouraging results. The spin-flavor symmetry is
used to predict some decay rates that have not yet been measured.Comment: 10 page
A relativistic chiral quark model for pseudoscalar emission from heavy mesons
The amplitudes for one-pion mediated transitions between heavy meson excited
states are obtained in the framework of the relativistic chiral quark model.
The effective coupling constants to pions and the decay widths of excited heavy
mesons with l<=2 for non-radially excited, and the l=0 radially excited mesons
are presented for both charmed and beauty mesons. We also discuss the allowed
decays of strange excited heavy mesons by emission of a K-meson.Comment: 20 pages, revte
Circular Optical Nanoantennas: An Analytical Theory
An entirely analytical theory is provided for describing the resonance
properties of optical nanoantennas made of a stack of homogeneous discs, i.e.
circular patch nanoantennas. It consists in analytically calculating the phase
accumulation of surface plasmon polaritons across the resonator and an
additional contribution from the complex reflection coefficient at the antenna
termination. This makes the theory self-contained with no need for fitting
parameters. The very antenna resonances are then explained by a simple
Fabry-Perot resonator model. Predictions are compared to rigorous simulations
and show excellent agreement. Using this analytical model, circular antennas
can be tuned by varying the composition of the stack
Distinct Signatures For Coulomb Blockade and Aharonov-Bohm Interference in Electronic Fabry-Perot Interferometers
Two distinct types of magnetoresistance oscillations are observed in two
electronic Fabry-Perot interferometers of different sizes in the integer
quantum Hall regime. Measuring these oscillations as a function of magnetic
field and gate voltages, we observe three signatures that distinguish the two
types. The oscillations observed in a 2.0 square micron device are understood
to arise from the Coulomb blockade mechanism, and those observed in an 18
square micron device from the Aharonov-Bohm mechanism. This work clarifies,
provides ways to distinguish, and demonstrates control over, these distinct
physical origins of resistance oscillations seen in electronic Fabry-Perot
interferometers.Comment: related papers at http://marcuslab.harvard.ed
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