The utility of screening for parasitic infections in HIV-1-infected Africans with eosinophilia in London.

The presence of asymptomatic eosinophilia in HIV patients has been demonstrated to have a wide variety of causes. Untreated parasitic infections in immunocompromised individuals can have potentially serious consequences. The utility of screening for parasitic infections in immigrant HIV-positive Africans with eosinophilia was investigated in a UK-based HIV clinic. HIV-positive African patients with eosinophilia were matched with HIV-positive African controls without eosinophilia. More than half of African HIV patients with eosinophilia had positive parasitic serology, and were significantly more likely to have positive serology compared with African HIV patients without eosinophilia. This study shows that asymptomatic eosinophilia in HIV-1-infected Africans is strongly suggestive of underlying parasitic infection. Individuals with eosinophilia should thus be screened for parasitic infections according to the infections prevalent in the countries they have lived in or visited for substantial periods of time

Uptake of school-based HTC.

<p>Uptake of school-based HTC.</p

Uptake of self-testing.

<p>Uptake of self-testing.</p

First time testers in community-based testing approaches for key populations.

<p>First time testers in community-based testing approaches for key populations.</p

Uptake of workplace HTC.

<p>Asterisk: data reported were from the Democratic Republic of Congo, Rwanda, Burundi, Congo, and Nigeria.</p

Number needed to screen to identify a person with HIV in studies offering community- and facility-based HTC.

<p>The Henry-Reid et al. <a href="http://www.plosmedicine.org/article/info:doi/10.1371/journal.pmed.1001496#pmed.1001496-HenryReid1" target="_blank">[87]</a> study was excluded since it did not find any people with HIV among the 20 school participants screened.</p

Uptake of door-to-door HTC.

<p>Asterisk: data reported were exclusively from children aged 18 mo.–13 y.</p

Summary of study participants and methods.

a<p>The midpoint was used for studies that took place over several years.</p>b<p>Among studies that included gender data.</p><p>IQR, interquartile range.</p