Combining univariate approaches for ensemble change detection in multivariate data

Detecting change in multivariate data is a challenging problem, especially when class labels are not available. There is a large body of research on univariate change detection, notably in control charts developed originally for engineering applications. We evaluate univariate change detection approaches —including those in the MOA framework — built into ensembles where each member observes a feature in the input space of an unsupervised change detection problem. We present a comparison between the ensemble combinations and three established ‘pure’ multivariate approaches over 96 data sets, and a case study on the KDD Cup 1999 network intrusion detection dataset. We found that ensemble combination of univariate methods consistently outperformed multivariate methods on the four experimental metrics.project RPG-2015-188 funded by The Leverhulme Trust, UK; Spanish Ministry of Economy and Competitiveness through project TIN 2015-67534-P and the Spanish Ministry of Education, Culture and Sport through Mobility Grant PRX16/00495. The 96 datasets were originally curated for use in the work of Fernández-Delgado et al. [53] and accessed from the personal web page of the author5. The KDD Cup 1999 dataset used in the case study was accessed from the UCI Machine Learning Repository [10

Abstracts of the 22nd International Isotope Society (UK Group) Symposium: synthesis and applications of labelled compounds 2013

Meeting Summary The 22nd annual symposium of the International Isotope Society's United Kingdom Group took place at the Møller Centre, Churchill College, Cambridge, UK, on Friday, 18 October 2013. The meeting was attended by 65 delegates from academia and industry; the life sciences; and chemical, radiochemical and scientific instrument suppliers.Delegates were welcomed by Dr Ken Lawrie (GlaxoSmithKline, UK, chair of the IIS UK group). The subsequent scientific programme consisted of oral and poster presentations on isotopic chemistry and applications of labelled compounds, or of chemistry with potential implications for isotopic synthesis. Both short‐lived and long‐lived isotopes were represented, as were stable isotopes. The symposium programme was divided into a morning session chaired by Dr Karl Cable (GlaxoSmithKline, UK) and afternoon sessions chaired by Mr Mike Chappelle (Quotient Biosciences, UK) and by Dr Nick Bushby (AstraZeneca, UK). The UK meeting concluded with remarks from Dr Ken Lawrie (GlaxoSmithKline, UK)