2 research outputs found
Mechanistic insights into transient severe mitral regurgitation
<p>Acute mitral regurgitation (AMR), a known complication of acute coronary syndromes, is usually associated with posterior papillary muscle dysfunction/rupture. In severe cases, management of AMR requires surgical intervention. Reversible severe AMR in patients in the absence of left ventricular systolic dysfunction and coronary artery stenosis may result from processes which cause transient subendocardial ischemia, such as intermittent episodes of hypotension or coronary artery vasospasm. We present two cases of reversible transient AMR due to subendocardial and/or endocardial ischemia, both of which offer insight into the mechanism of transient severe AMR.</p
Visual representation of significant cytokine differences when comparing effusive with effusive-constrictive tuberculous pericarditis in the blood and pericardial fluid compartments (see Table 2 for results of all cytokines).
<p>Each colored disc represents the median value for the particular cytokine; the areas are proportional to the concentration of the cytokine. IL-10, interleukin 10; TGF- β, transforming growth factor beta; IFN- <b>γ</b>, interferon gamma.</p