Fertility and hatchability potentials of ShikaBrown® chickens and effect of body weight and age of chicken on egg quality traits in southwestern, Nigeria

The study was conducted to assess the reproductive performance and the effect of body weight and age on external egg quality  traits of ShikaBrown® (SS-98, SG-98 and SB-98) chickens. Six hundred ShikaBrown® chickens fertile eggs were sourced, incubated and 21 weeks old ShikaBrown® layers were used for studying some external egg quality traits. Data collected were  subjected to Analysis of Variance (SAS 9); Univariate was applied to test the effects of age and body weight on  external egg  quality traits of the birds; where significant differences occurred, the means were separated by Duncan Multiple Range test. The dam (SS-98) parent stock had higher fertility (95.9%) while ShikaBrown® (SB-98) commercial layers had highest hatchability (89.9%). There was significant effect of age and body weight on all the external egg quality traits (p<0.05) considered in this  study except egg shape index, which was not significantly affected (p>0.05) by body weight. The external egg quality traits  progressed with corresponding increase in the age and body weight of the ShikaBrown® (SB-98) layers. On the basis of the  recorded high values for both reproduction and egg quality traits, the ShikaBrown® parent lines and commercial layers should be made readily available to the commercial poultry farms.Keywords: Egg, Hatchability, Fertility, External quality traits, ShikaBrown® chicken genotypes (SS-98, SG-98, SB-98)

The mechanisms of coronary restenosis: insights from experimental models

Since its introduction into clinical practice, more than 20 years ago, percutaneous transluminal coronary angioplasty (PTCA) has proven to be an effective, minimally invasive alternative to coronary artery bypass grafting (CABG). During this time there have been great improvements in the design of balloon catheters, operative procedures and adjuvant drug therapy, and this has resulted in low rates of primary failure and short-term complications. However, the potential benefits of angioplasty are diminished by the high rate of recurrent disease. Up to 40% of patients undergoing angioplasty develop clinically significant restenosis within a year of the procedure. Although the deployment of endovascular stents at the time of angioplasty improves the short-term outcome, ‘in-stent’ stenosis remains an enduring problem. In order to gain an insight into the mechanisms of restenosis, several experimental models of angioplasty have been developed. These have been used together with the tools provided by recent advances in molecular biology and catheter design to investigate restenosis in detail. It is now possible to deliver highly specific molecular antagonists, such as antisense gene sequences, to the site of injury. The knowledge provided by these studies may ultimately lead to novel forms of intervention. The present review is a synopsis of our current understanding of the pathological mechanisms of restenosis