Osgood-Schlatter disease and potential treatment

Background: Aseptic necrosis of the tibial tuberosity, also known as Osgood-Schlatter disease, is one of the more common causes of pain in the tibia area in children and adolescents. The pathology is much more common in boys than in girls. Young athletes, including training footballers, basketball players and volleyball players, as well as children who actively spend their free time are particularly exposed to the development of the disease.  Material and methods: This paper was based on medical articles collected in PubMed , medical websites and books. The research has been done by looking through key words such as:’’ Osgood-Schlatter disease”,’’Osgood-Schlatter treatment”  Results: Osgood-Schlatter disease is usually self-limiting. In the absence of symptom relief, there are operational methods, which, however, are ambiguous.  Conclusions: Treatment of OSD patients and a challenge for healthcare professionals.&nbsp

Osteogenesis imperfecta and potential therapies

Background: Osteogenesis imperfecta (OI) is a genetically determined disorder of connective tissue. In this article we reviewed epidemiology, types of OI, pathophysiology, symptoms and potential therapies.Material and methods: This paper was based on medical articles collected in PubMed from 2006 to 2022, medical websites and books. The research has been done by looking through key words such as: „osteogenesis imperfecta”, „osteogenesis imperfecta treatment”, „bisphosphonate”, „sillence classification”.Results: The pathophysiology of osteogenesis imperfecta is well understood. Treatment and symptoms of the disease depend on the type of osteogenesis imperfecta.Conclusions: Treatment of the patients with OI is challenging for health care professionals. Medical care for majority of patients with OI extends their life and improves its quality. Despite advances in science, causal treatment still does not exist