Additional file 1 of A soft, scalable and adaptable multi-contact cuff electrode for targeted peripheral nerve modulation

Additional file 1

RV ESTVI-LV contractility relationship during changes in different loading conditions.

<p>Correlations between changes in RV end systolic TVI (ESTVI) and in left ventricular (LV) stroke volume (SV) or maximum of the first derivative of LV pressure (dP/dt_max) during preload reduction (A,B) and increase of LV afterload (C, D). Changes normalized to baseline values.</p

ESTVI (A), EDTVI (B) and pk-pk TVI (C) changes during different loading and inotropic conditions. * <i>p</i><0.05 vs baseline; # <i>p</i><0.05 vs LDDS.

<p>ESTVI (A), EDTVI (B) and pk-pk TVI (C) changes during different loading and inotropic conditions. * <i>p</i><0.05 vs baseline; # <i>p</i><0.05 vs LDDS.</p

Absolute values and percentage changes in contractile indices compared with respective baseline values during inotropic modulation.

<p>Mean values±S.E.M. n = 6. ESTVI, end-systolic TVI; EDTVI, end-diastolic TVI; pk-pk TVI, peak to peak TVI; HR, heart rate; MAP, mean arterial pressare; LVESP, left ventricular end-systolic pressure; LVEDP, left ventricular end-diastolic pressure; LVESV, left ventricular end-systolic volume; LVEDV, left ventricular end-diastolic volume; LVSW, left ventricular stroke work; Ea, arterial elastance; Ees, end-systolic elastance. * P<0.05 vs baseline; #P<0.05 vs LDDS.</p

Absolute values and percentage changes compared with respective baseline values during changes in loading conditions.

<p>Mean values±S.E.M. n = 6. ESTVI, end-systolic TVI; EDTVI, end-diastolic TVI; pk-pk TVI, peak to peak TVI; HR, heart rate; MAP, mean arterial pressare; LVESP, left ventricular end-systolic pressure; LVEDP, left ventricular end-diastolic pressure; LVESV, left ventricular end-systolic volume; LVEDV, left ventricular end-diastolic volume; LVSW, left ventricular stroke work; Ea, arterial elastance; Ees, end-systolic elastance. * P<0.05 vs baseline; #P<0.05 vs acute preload reduction.</p

RV ESTVI-LV contractility relationship during changes in different inotropic conditions.

<p>Correlations between changes in RV end systolic TVI (ESTVI) and in left ventricular (LV) stroke volume (SV) or in maximum of the first derivative of LV pressure (dP/dt_max) during low dose dobutamine stress (LDDS) (A,B) and following esmolol infusion (C, D). Changes normalized to baseline values.</p

RV ESTVI- LV Ees relationship during changes in different loading and inotropic conditions.

<p>Correlation between changes in RV end-systolic TVI (ESTVI) and left ventricular Ees during preload reduction (A), increase of afterload (B), low dose dobutamine stress (C) and following esmolol infusion (D). Changes normalized to baseline values.</p