Towards a More Holistic Understanding of American Support for Genetically Modified Crops: An Examination of Influential Factors Using a Binomial Dependent Variable

This paper is an investigation into the relative importance of a wide variety of factors in influencing whether members of the American public support or oppose the use of biotechnology in agriculture and food production. To accomplish this end, as well as to facilitate the examination of a large number of independent variables simultaneously, several statistical methods, including factor analyses, instrumental variables analysis, and probit and logistic regressions were performed. It was determined that people’s perceptions of risks and moral acceptability were important contributors to opinion formation in this regard. The effects of expected benefits, feelings of trust in information, and knowledge about biotechnology and genetics, were also investigated and found to exert varying levels of influence depending on the identity of the expected beneficiary or information source, as well as the kind of knowledge under consideration. The roles of religious and political party affiliation were also examined and determined to be significant.genetically modified foods, biotechnology, public opinion

The Scholarship and Practice of an Integrated Communication Education (SPICE)

This dissertation explores the scholarship and practice of an integrated communication education. Specifically, it explores the contributions made by scholarship in the writing-across-the-curriculum (WAC) and learning community (LC) movements and in the areas of collaboration, and multimodal communication instruction to the development of an integrated communication curriculum. This innovative communication education responds to the changing nature of communication in the 21st century. After a literature review of this relevant scholarship (Part I), this dissertation includes an account of one curricular initiative, ISUComm, informed by this pedagogical research (Part II). Particular attention is paid in the penultimate chapter to the professional development of instructors in an integrated communication curriculum. Implications and further research are discussed in the final chapter.*;*This dissertation is a compound document (contains both a paper copy and a CD as part of the dissertation). The CD requires the following system requirements: Adobe Acrobat

Towards a More Holistic Understanding of American Support for Genetically Modified Crops: An Examination of Influential Factors Using a Binomial Dependent Variable

This paper is an investigation into the relative importance of a wide variety of factors in influencing whether members of the American public support or oppose the use of biotechnology in agriculture and food production. To accomplish this end, as well as to facilitate the examination of a large number of independent variables simultaneously, several statistical methods, including factor analyses, instrumental variables analysis, and probit and logistic regressions were performed. It was determined that people’s perceptions of risks and moral acceptability were important contributors to opinion formation in this regard. The effects of expected benefits, feelings of trust in information, and knowledge about biotechnology and genetics, were also investigated and found to exert varying levels of influence depending on the identity of the expected beneficiary or information source, as well as the kind of knowledge under consideration. The roles of religious and political party affiliation were also examined and determined to be significant

ADP-heptose enables Helicobacter pylori to exploit macrophages as a survival niche by suppressing antigen-presenting HLA-II expression

The persistence of Helicobacter pylori in the human gastric mucosa implies that the immune response fails to clear the infection. We found that H. pylori compromises the antigen presentation ability of macrophages, because of the decline of the presenting molecules HLA-II. Here, we reveal that the main bacterial factor responsible for this effect is ADP-heptose, an intermediate metabolite in the biosynthetic pathway of lipopolysaccharide (LPS) that elicits a pro-inflammatory response in gastric epithelial cells. In macrophages, it upregulates the expression of miR146b which, in turn, would downmodulate CIITA, the master regulator for HLA-II genes. Hence, H. pylori, utilizing ADP-heptose, exploits a specific arm of macrophage response to establish its survival niche in the face of the immune defense elicited in the gastric mucosa

Effects of seawater and freshwater challenges on the Gh/Igf system in the saline-tolerant blackchin tilapia (Sarotherodon melanotheron)

Prolactin (Prl) and growth hormone (Gh) as well as insulin-like growth factor 1 (Igf1) are involved in the physiological adaptation of fish to varying salinities. The Igfs have been also ascribed other physiological roles during development, growth, reproduction and immune regulation. However, the main emphasis in the investigation of osmoregulatory responses has been the endocrine, liver-derived Igf1 route and local regulation within the liver and osmoregulatory organs. Few studies have focused on the impact of salinity alterations on the Gh/Igf-system within the neuroendocrine and immune systems and particularly in a salinity-tolerant species, such as the blackchin tilapia Sarotherodon melanotheron. This species is tolerant to hypersalinity and saline variations, but it is confronted by severe climate changes in the Saloum inverse estuary. Here we investigated bidirectional effects of increased salinity followed by its decrease on the gene regulation of prl, gh, igf1, igf2, Gh receptor and the tumor-necrosis factor a. A mixed population of sexually mature 14-month old blackchin tilapia adapted to freshwater were first exposed to seawater for one week and then to fresh water for another week. Brain, pituitary, head kidney and spleen were excised at 4 h, 1, 2, 3 and 7 days after both exposures and revealed differential expression patterns. This investigation should give us a better understanding of the role of the Gh/Igf system within the neuroendocrine and immune organs and the impact of bidirectional saline challenges on fish osmoregulation in non-osmoregulatory organs, notably the complex orchestration of growth factors and cytokines

[tiger2] As a standardized serialisation for ISO 24615 - SynAF

International audienceThis paper presents the application of the format to various linguistic scenarios with the aim of making it the standard serialisation for the ISO 24615 (SynAF) standard. After outlining the main characteristics of both the SynAF metamodel and the format, as extended from the initial Tiger XML format (König & Lezius, 2000), we show through a range of different language families how covers a variety of constituency and dependency based analyses.Cet article présente l'application du format pour divers scenari linguistiques dans le but de l'utiliser comme sérialisation de la norme ISO 24615 (SynAF). Après un rappel des caractéristiques principales du métamodèle de SynAF et du format , en tant qu'extension du format originel Tiger XML (König & Lezius, 2000), nous montrons au travers d'un panel de différentes familles de langues comment couvre une large gamme d'analyses syntaxiques fondées sur des constituants et sur des dépendances

Endocrine Active UV Filters: Developmental Toxicity and Exposure Through Breast Milk

Several UV filters exhibit endocrine activity. Evidence for transdermal passage and presence in the food chain (fish) suggests potential exposure of humans during development. Developmental toxicity was studied in rats for the estrogenic UV filters 4-methylbenzylidene camphor (4-MBC, 0.7, 7, 24, 47 mg/kg/day) and 3-benzylidene camphor (3-BC, 0.07, 0.24, 0.7, 2.4, 7 mg/kg/day) administered in chow to the parent generation before mating, during pregnancy and lactation, and to the offspring until adulthood. Neonates exhibited enhanced prostate growth after 4-MBC and altered uterine gene expression after both filters. 4-MBC and 3-BC delayed male puberty and affected reproductive organ weights of adult offspring. Interactions with the thyroid were noted. Expression and estrogen sensitivity of target genes and nuclear receptor coregulators were altered at mRNA and protein levels in adult uterus, prostate and brain. Female sexual behavior was affected by 4-MBC and 3-BC, estrous cycles by 3-BC. Classical endpoints exhibited LOAELs/NOAELs of 7/0.7 mg/kg/day for 4-MBC and 0.24/0.07 mg/kg/day for 3-BC. Molecular endpoints were affected by the lowest doses. In order to obtain information on human exposure, we conducted a monitoring study on human milk with three series of mother–child pairs (2004, 2005, 2006), with focus on cosmetic UV filters in relation to other endocrine disrupters. Methods for UV filter analysis followed the principles of European standardized methods for pesticide residue analysis (EN 15289). In cohorts 2004 and 2005, 78.8% of women reported use of product(s) containing cosmetic UV filters in a questionnaire, and 76.5% of milk samples contained these filters. Use of UV filters and concentration in human milk were significantly correlated. The results agree with the idea of transdermal passage of UV filters. They also indicate that it may be possible to reduce human exposure during critical periods such as pregnancy and lactation by transiently abstaining from use