9 research outputs found

    All-Optical Generation of Surface Plasmons in Graphene

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    27 pages, 12 figures, includes supplementary materialarXiv is an e-print service in the fields of physics, mathematics, computer science, quantitative biology, quantitative finance and statistics.Here we present an all-optical plasmon coupling scheme, utilising the intrinsic nonlinear optical response of graphene. We demonstrate coupling of free-space, visible light pulses to the surface plasmons in a planar, un-patterned graphene sheet by using nonlinear wave mixing to match both the wavevector and energy of the surface wave. By carefully controlling the phase-matching conditions, we show that one can excite surface plasmons with a defined wavevector and direction across a large frequency range, with an estimated photon efficiency in our experiments approaching 10−510^{-5}

    Prophylactic use of aspirin: systematic review of harms and approaches to mitigation in the general population

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    The review was sponsored by International Society of Cancer Prevention (ISCaP), Cancer Research UK (CRUK), British Heart Foundation (BHF) and American Cancer Society (ACS) and received funding from CRUK, BHF and AC

    Drug-Induced Liver Injury: Pattern Recognition and Future Directions

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    Drug-induced liver injury (DILI) remains a significant clinical challenge and is the leading cause of acute liver failure in most countries. An aging population that uses more medica-tions, a constant influx of newly developed drugs and a grow-ing risk from unfamiliar herbal and dietary supplements will make DILI an increasing part of clinical practice. Currently, the most effective strategy for disease management is rapid identification, withholding the inciting agents, supportive care and having a firm understanding of the expected natu-ral history. There are resources available to aid the clinician, including a new online “textbook ” as well as causality as-sessment tools, but a heightened awareness of risk and the disease’s varying phenotypes and good history-taking remain cornerstones to diagnosis. Looking ahead, growing registries of cases, pharmacoepidemiology studies and translational research into the mechanisms of injury may produce better diagnostic tools, markers for risk and disease, and preven-tion and therapeutics. (Gut Liver 2016;10:27-36
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