36 research outputs found
Les caractéristiques de l'acte d'achat et la logique du marketing amont
International audienceDe nombreux travaux l'indiquent, les similitudes qui apparaissent entre la vente et l'achat garantissent la pertinence du concept de marketing amont. Cependant, les particularités de l'acte d'achat confirent certaines spécificités au marketing de l'acheteur. La logique d'action qui le caractérise comporte incontestablement une composante adaptative;mais elle doit également s'appuyer sur l'utilisation de mécanismes de pouvoir. La stimulation de la concurrence entre les fournisseurs et le partenariat sont les instruments les plus puissants dont les entreprises disposent pour inciter les fournisseurs à tenir compte de leurs besoins;employés sans coercition ils constituent les principaux ressorts de l'action marketing des acheteurs
Dyadic Interaction and Organisational Learning. An Empirical Examination of the French Food Industry
International audienc
Dyadic Interaction and Organisational Learning. An Empirical Examination of the French Food Industry
International audienc
A dyserythropoietic anemia associated with homozygous Hb Plasencia [α125(H8)Leu→Arg (α2)] (HBA2:c.377T>G), a variant with an unstable α chain.
A female patient of Portuguese origin, who was born to consanguineous parents, presented with
moderate anemia, mild jaundice and splenomegaly. Bone marrow aspiration showed an erythroid
hyperplasia and binucleate erythroblasts, evoking a congenital dyserythropoietic anemia, type II
(CDA II). Although microcytosis cast some doubt on the diagnosis, investigation was pursued along
this line. The CDA II was finally ruled out as underglycosylation of band 3, remnants of endoplasmic
reticulum cisternae and mutations in the SEC23B gene were all missing. On the other
hand, analysis of the α-globin genes showed a base substitution at codon 125 (CTG→CGG) of the
α2-globin gene, ascertaining a homozygosity for Hb Plasencia (HBA2:c.377T>G). This variant
has an unstable α chain. In the absence of a thorough work-up, dyserythropoietic anemia associated
with hemoglobin (Hb) variants having a moderately unstable α chain, may be mistaken for CDA II