201 research outputs found
Equation of state of hard oblate ellipsoids by replica exchange Monte Carlo
We implemented the replica exchange Monte Carlo technique to produce the
equation of state of hard 1:5 aspect-ratio oblate ellipsoids for a wide density
range. For this purpose, we considered the analytical approximation of the
overlap distance given by Bern and Pechukas and the exact numerical solution
given by Perram and Wertheim. For both cases we capture the expected
isotropic-nematic transition at low densities and a nematic-crystal transition
at larger densities. For the exact case, these transitions occur at the volume
fraction 0.341, and in the interval , respectively.Comment: 4 pages, 2 figure
Eficiencia alimentaria en sistemas de producción de leche con pariciones concentradas al inicio del período de máximo crecimiento de la hierba
Twenty-six dairy farms having an area between 93,5 ha and 112,1 ha, and a herd ranging from 109 to 126 cows were sampled to evaluate feeding efficiency based on variations in calving compaction levels at the beginning of the highest grass growing season. These farms are affiliated to six livestock production centers from Camagüey and Jimaguayú and located at 21,5° N and 71,2° W, 93 m above sea level. Soils are classified as types 2 and 3 within the agroproductive category. Climate is humid tropical complementary to inland plains. The mean annual rainfall is 1095 mm with 67 % of rains between April and October. The dairy farms calving percentages from April to August were registered according to three patterns: PI = 43 - 56 %, PII = 58 - 68 %, PIII = 70 - 82 %. Performance of feeding efficiency indicators was better (p<0,05) for PIII with a higher calving compaction level showing values of 0,48 milk/forage tons and 0,44 milk tons/food tons/cow compared to values for PI and PII. In addition, fat + protein production also reached higher values for PIII (p<0,05), i.e., 94 kg/cow/and 106 kg/ha. Findings support that feeding process is more efficient when calving compaction levels are higher and pastures and forage nutritional utilization is also higher.El objetivo del trabajo fue evaluar la eficiencia alimentaria de seis cooperativas ganaderas de Camagüey y Jimaguayú con diferentes concentraciones de sus partos al inicio de la época de máximo crecimiento de la hierba. Se usó la información registrada en seis cooperativas de estos territorios, ubicados a los 21,50 Norte y 71,20 Oeste, aproximadamente a 93 msnm con suelos de categoría agroproductiva 2 y 3 en el período comprendido entre abril de 2002 y marzo de 2009. El clima es tropical húmedo de llanura interior, con 1 095 mm de precipitación anual y el 67 % de las lluvias ocurriendo entre abril y octubre. Las 26 vaquerías escogidas tienen un área entre 93,5 y 112,1 ha y un rango de 109 a 126 vacas. La conformación de los patrones fue el siguiente: PI= 43 a 56 % de partos entre abril y agosto; PII= 58 a 68 % de partos entre abril y agosto; PIII= 70 a 82 % entre abril y agosto. Los mejores indicadores de eficiencia alimentaria (P < 0,05) se obtuvieron en el PIII con mayor concentración de partos en ese período, que presenta valores de 0,48 t de leche/t de forraje y de 0,44 t de leche/t de alimento total/vaca frente a valores menores en el resto de lo patrones. La producción de grasa+proteínas alcanzó valores de 94 kg/vaca y 106 kg/ha en el PIII, superiores (P < 0,05) a los restantes patrones, lo cual es consecuencia favorable de la mayor concentración de pariciones y mejor aprovechamiento de los aportes nutricionales de los pastos y forrajes en su época de mayor crecimiento; esto hace más eficiente el proceso alimentario
Baseline Inflammatory Status Reveals Dichotomic Immune Mechanisms Involved In Primary-Progressive Multiple Sclerosis Pathology
To ascertain the role of inflammation in the response to ocrelizumab in primary-progressive multiple sclerosis (PPMS).Multicenter prospective study including 69 patients with PPMS who initiated ocrelizumab treatment, classified according to baseline presence [Gd+, n=16] or absence [Gd-, n=53] of gadolinium-enhancing lesions in brain MRI. Ten Gd+ (62.5%) and 41 Gd- patients (77.4%) showed non-evidence of disease activity (NEDA) defined as no disability progression or new MRI lesions after 1 year of treatment. Blood immune cell subsets were characterized by flow cytometry, serum immunoglobulins by nephelometry, and serum neurofilament light-chains (sNfL) by SIMOA. Statistical analyses were corrected with the Bonferroni formula.More than 60% of patients reached NEDA after a year of treatment, regardless of their baseline characteristics. In Gd+ patients, it associated with a low repopulation rate of inflammatory B cells accompanied by a reduction of sNfL values 6 months after their first ocrelizumab dose. Patients in Gd- group also had low B cell numbers and sNfL values 6 months after initiating treatment, independent of their treatment response. In these patients, NEDA status was associated with a tolerogenic remodeling of the T and innate immune cell compartments, and with a clear increase of serum IgA levels.Baseline inflammation influences which immunological pathways predominate in patients with PPMS. Inflammatory B cells played a pivotal role in the Gd+ group and inflammatory T and innate immune cells in Gd- patients. B cell depletion can modulate both mechanisms.Copyright © 2022 Fernández-Velasco, Monreal, Kuhle, Meca-Lallana, Meca-Lallana, Izquierdo, Oreja-Guevara, Gascón-Giménez, Sainz de la Maza, Walo-Delgado, Lapuente-Suanzes, Maceski, Rodríguez-Martín, Roldán, Villarrubia, Saiz, Blanco, Diaz-Pérez, Valero-López, Diaz-Diaz, Aladro, Brieva, Íñiguez, González-Suárez, Rodríguez de Antonio, García-Domínguez, Sabin, Llufriu, Masjuan, Costa-Frossard and Villar
Multiplicity dependence of jet-like two-particle correlations in p-Pb collisions at = 5.02 TeV
Two-particle angular correlations between unidentified charged trigger and
associated particles are measured by the ALICE detector in p-Pb collisions at a
nucleon-nucleon centre-of-mass energy of 5.02 TeV. The transverse-momentum
range 0.7 5.0 GeV/ is examined,
to include correlations induced by jets originating from low
momen\-tum-transfer scatterings (minijets). The correlations expressed as
associated yield per trigger particle are obtained in the pseudorapidity range
. The near-side long-range pseudorapidity correlations observed in
high-multiplicity p-Pb collisions are subtracted from both near-side
short-range and away-side correlations in order to remove the non-jet-like
components. The yields in the jet-like peaks are found to be invariant with
event multiplicity with the exception of events with low multiplicity. This
invariance is consistent with the particles being produced via the incoherent
fragmentation of multiple parton--parton scatterings, while the yield related
to the previously observed ridge structures is not jet-related. The number of
uncorrelated sources of particle production is found to increase linearly with
multiplicity, suggesting no saturation of the number of multi-parton
interactions even in the highest multiplicity p-Pb collisions. Further, the
number scales in the intermediate multiplicity region with the number of binary
nucleon-nucleon collisions estimated with a Glauber Monte-Carlo simulation.Comment: 23 pages, 6 captioned figures, 1 table, authors from page 17,
published version, figures at
http://aliceinfo.cern.ch/ArtSubmission/node/161
Charge separation relative to the reaction plane in Pb-Pb collisions at TeV
Measurements of charge dependent azimuthal correlations with the ALICE
detector at the LHC are reported for Pb-Pb collisions at TeV. Two- and three-particle charge-dependent azimuthal correlations in
the pseudo-rapidity range are presented as a function of the
collision centrality, particle separation in pseudo-rapidity, and transverse
momentum. A clear signal compatible with a charge-dependent separation relative
to the reaction plane is observed, which shows little or no collision energy
dependence when compared to measurements at RHIC energies. This provides a new
insight for understanding the nature of the charge dependent azimuthal
correlations observed at RHIC and LHC energies.Comment: 12 pages, 3 captioned figures, authors from page 2 to 6, published
version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/286
A note on comonotonicity and positivity of the control components of decoupled quadratic FBSDE
In this small note we are concerned with the solution of Forward-Backward
Stochastic Differential Equations (FBSDE) with drivers that grow quadratically
in the control component (quadratic growth FBSDE or qgFBSDE). The main theorem
is a comparison result that allows comparing componentwise the signs of the
control processes of two different qgFBSDE. As a byproduct one obtains
conditions that allow establishing the positivity of the control process.Comment: accepted for publicatio
Transverse sphericity of primary charged particles in minimum bias proton-proton collisions at , 2.76 and 7 TeV
Measurements of the sphericity of primary charged particles in minimum bias
proton--proton collisions at , 2.76 and 7 TeV with the ALICE
detector at the LHC are presented. The observable is linearized to be collinear
safe and is measured in the plane perpendicular to the beam direction using
primary charged tracks with GeV/c in . The
mean sphericity as a function of the charged particle multiplicity at
mid-rapidity () is reported for events with different
scales ("soft" and "hard") defined by the transverse momentum of the leading
particle. In addition, the mean charged particle transverse momentum versus
multiplicity is presented for the different event classes, and the sphericity
distributions in bins of multiplicity are presented. The data are compared with
calculations of standard Monte Carlo event generators. The transverse
sphericity is found to grow with multiplicity at all collision energies, with a
steeper rise at low , whereas the event generators show the
opposite tendency. The combined study of the sphericity and the mean with multiplicity indicates that most of the tested event generators
produce events with higher multiplicity by generating more back-to-back jets
resulting in decreased sphericity (and isotropy). The PYTHIA6 generator with
tune PERUGIA-2011 exhibits a noticeable improvement in describing the data,
compared to the other tested generators.Comment: 21 pages, 9 captioned figures, 3 tables, authors from page 16,
published version, figures from
http://aliceinfo.cern.ch/ArtSubmission/node/308
Anisotropic flow of charged hadrons, pions and (anti-)protons measured at high transverse momentum in Pb-Pb collisions at TeV
The elliptic, , triangular, , and quadrangular, , azimuthal
anisotropic flow coefficients are measured for unidentified charged particles,
pions and (anti-)protons in Pb-Pb collisions at TeV
with the ALICE detector at the Large Hadron Collider. Results obtained with the
event plane and four-particle cumulant methods are reported for the
pseudo-rapidity range at different collision centralities and as a
function of transverse momentum, , out to GeV/.
The observed non-zero elliptic and triangular flow depends only weakly on
transverse momentum for GeV/. The small dependence
of the difference between elliptic flow results obtained from the event plane
and four-particle cumulant methods suggests a common origin of flow
fluctuations up to GeV/. The magnitude of the (anti-)proton
elliptic and triangular flow is larger than that of pions out to at least
GeV/ indicating that the particle type dependence persists out
to high .Comment: 16 pages, 5 captioned figures, authors from page 11, published
version, figures at http://aliceinfo.cern.ch/ArtSubmission/node/186
- …