The Relationship between Gestational Diabetes and Polycystic Ovary Syndrome

BACKGROUND AND OBJECTIVE: Women with polycystic ovary syndrome (PCOS) are at risk of insulin resistance and pregnancy complications. The aim of this study is to determine the relationship between gestational diabetes and polycystic ovary syndrome. METHODS: This cross-sectional study was performed on 126 pregnant women with PCOS and infertility history who became pregnant after stimulation of ovulation and referred to Imam Khomeini Hospital in Ahvaz. These patients underwent screening with 75 g OGTT (Oral Glucose Tolerance Test) during the first trimester and during 24-28 weeks of gestation. They were divided into two groups of PCOS with gestational diabetes and without gestational diabetes. Variables such as age, gestational diabetes, parity and BMI were measured and the relationship between BMI and gestational diabetes was examined. FINDINGS: The mean age of patients in the two PCOS groups with and without gestational diabetes was 26.09±2.03 and 27.07±3.03 years, respectively. Of the 126 pregnant women with PCOS, 30 (23.8%) patients were diagnosed with gestational diabetes in the first trimester of pregnancy and 11 (8.7%) patients during 24-28 weeks of gestation. Overall, 41(32.5%) patients had gestational diabetes and 85 (67.5%) patients did not have gestational diabetes. There was no significant difference in the mean BMI between the two PCOS groups with and without gestational diabetes. CONCLUSION: The results of the study showed that more than one third of women with PCOS experience gestational diabetes during pregnancy

Seroprevalence of Toxoplasma gondii

Toxoplasma gondii is an obligate intracellular protozoan parasite causing toxoplasmosis in animals and humans. Primary maternal infection with toxoplasmosis during pregnancy is frequently associated with transplacental transmission to the fetus. However it is not certain whether Toxoplasma infection can cause recurrent abortion. The aim of this study was to determine the relationship between Toxoplasma infection and abortion via detection of anti-Toxoplasma gondii antibodies in sera of women with obstetrical problems and compare the results with control group consisting of women with history of normal delivery. Sera from 130 women with abortion and sera of 130 women with normal delivery were tested for IgG and IgM anti-Toxoplasma gondii antibodies by ELISA method. The present study revealed 24.6% of the samples with abortion and 21.5% of the samples with normal delivery were positive for IgG antibodies. However, statistical analysis indicated no significant differences (P>0.05). In addition, IgM antibody was detected in one woman who had aborted but not in women with normal childbirth. This study showed no significant difference between the case and control groups in IgG anti-Toxoplasma antibody but detected one sample with IgM antibodies in woman with abortion during the first trimester of pregnancy. In order to determine the relationship between Toxoplasma infection and abortion, anti-Toxoplasma IgG avidity and PCR to discriminate between recent and prior infections are recommended

Mean Duration of Pregnancy in Spontaneous Deliveries in Ahwaz University Affiliated Hospitals in 2007

Abstract: Background & Aims: Accurate knowledge about gestational age is very important in taking decision for pregnancy management and termination. According to Naegele’s rule the length of pregnancy is 280 days after LMP and according to studies performed in Harvard University, duration of pregnancy in nullipare and multipare women has been respectively 288 and 283 days and according to a study performed in Oxford University it is influenced by factors such as age, parity, some illnesses and personal habits. Materials and methods: In this retrospective study, all laboring women admitted in Ahwaz Medical University Hospitals in 2007 including 689 nulliparas and 774 multiparas with true labor pain and reliable LMP were studied for pregnancy duration. Data were analyzed by SPSS software. Results: Mean duration of pregnancy was 273.17, 274.31and 273.77 days in nulliparas, multiparas and overall respectively. Parity has no significant association with pregnancy duration. According to the sonography below 26 weeks duration of pregnancy is calculated 270.07 days which had no significant relationship with LMP. Conclusion: According to this study parity has no effect on pregnancy duration. Mean pregnancy duration was shorter comapared to Naegele’s rule and Harvard University studies. Keywords: Gestational age, Labor, Parit