Coordinate Confusion in Conformal Cosmology

A straight-forward interpretation of standard Friedmann-Lemaitre-Robertson-Walker (FLRW) cosmologies is that objects move apart due to the expansion of space, and that sufficiently distant galaxies must be receding at velocities exceeding the speed of light. Recently, however, it has been suggested that a simple transformation into conformal coordinates can remove superluminal recession velocities, and hence the concept of the expansion of space should be abandoned. This work demonstrates that such conformal transformations do not eliminate superluminal recession velocities for open or flat matter-only FRLW cosmologies, and all possess superluminal expansion. Hence, the attack on the concept of the expansion of space based on this is poorly founded. This work concludes by emphasizing that the expansion of space is perfectly valid in the general relativistic framework, however, asking the question of whether space really expands is a futile exercise.Comment: 5 pages, accepted for publication in MNRAS Letter

Work-related psychological health and psychological type among lead elders within the Newfrontiers network of churches in the United Kingdom

Building on a series of recent studies concerned with assessing work-related psychological health and psychological type among various groups of church leaders, this study reports new data provided by 134 Lead Elders within the Newfrontiers network of churches in the United Kingdom who completed the Francis Psychological Type Scales (FPTS) together with the two scales of the Francis Burnout Inventory (FBI) concerned with emotional exhaustion and satisfaction in ministry. Compared with other groups of church leaders, Lead Elders within the Newfrontiers network of churches reported lower levels of emotional exhaustion and higher levels of satisfaction in ministry. Compared with other groups of church leaders, there was a higher proportion of extraverts among Lead Elders within the Newfrontiers network of churches. There was only a weak association between psychological type and burnout

Joining the Hubble Flow: Implications for Expanding Space

The concept of expanding space has come under fire recently as being inadequate and even misleading in describing the motion of test particles in the universe. Previous investigations have suffered from a number of shortcomings, which we seek to correct. We study the motion of test particles in the universe in detail, solving the geodesic equations of General Relativity for a number of cosmological models. In particular, we use analytic methods to examine whether particles removed from the Hubble flow asymptotically rejoin the Hubble flow, a topic that has caused confusion because of differing definitions and invalid reasoning. We conclude that particles in eternally expanding but otherwise arbitrary universes do not in general rejoin the Hubble flow

Strong to weak coupling transitions of SU(N) gauge theories in 2+1 dimensions

We investigate strong-to-weak coupling transitions in D=2+1 SU(N->oo) gauge theories, by simulating lattice theories with a Wilson plaquette action. We find that there is a strong-to-weak coupling cross-over in the lattice theory that appears to become a third-order phase transition at N=oo, in a manner that is essentially identical to the Gross-Witten transition in the D=1+1 SU(oo) lattice gauge theory. There is also evidence for a second order transition at N=oo at approximately the same coupling, which is connected with centre monopoles (instantons) and so analogues to the first order bulk transition that occurs in D=3+1 lattice gauge theories for N>4. We show that as the lattice spacing is reduced, the N=oo gauge theory on a finite 3-torus suffers a sequence of (apparently) first-order ZN symmetry breaking transitions associated with each of the tori (ordered by size). We discuss how these transitions can be understood in terms of a sequence of deconfining transitions on ever-more dimensionally reduced gauge theories.We investigate whether the trace of the Wilson loop has a non-analyticity in the coupling at some critical area, but find no evidence for this although, just as in D=1+1,the eigenvalue density of a Wilson loop forms a gap at N=oo for a critical trace. The physical implications of this are unclear.The gap formation is a special case of a remarkable similarity between the eigenvalue spectra of Wilson loops in D=1+1 and D=2+1 (and indeed D=3+1): for the same value of the trace, the eigenvalue spectra are nearly identical.This holds for finite as well as infinite N; irrespective of the Wilson loop size in lattice units; and for Polyakov as well as Wilson loops.Comment: 44 pages, 28 figures. Extensive changes and clarifications with new results on non-analyticities and eigenvalue spectra of Wilson loops. This version to be submitted for publicatio

Work-related psychological health and psychological type : a study among Catholic priests in Italy

This paper explores the connection between psychological type and burnout among a sample of 155 Catholic priests serving in Italy. Burnout was assessed by the Francis Burnout Inventory that draws on Bradburn's classic model of balanced affect to conceptualise poor work-related psychological health (burnout) in terms of high levels of emotional exhaustion in ministry in the absence of good levels of satisfaction in ministry. Psychological type was assessed by the Francis Psychological Type Scales that draw on the development of Jung's classic model that distinguishes between two orientations (extraversion and introversion), two perceiving functions (sensing and intuition), two judging functions (thinking and feeling), and two attitudes (judging and perceiving). The data demonstrated that higher levels of burnout were experienced by introverts than by extraverts. These findings are consistent with the view that the clerical profession has been shaped by inter-personal expectations that are more readily met by extraverts

IceCube-Plus: An Ultra-High Energy Neutrino Telescope

While the first kilometer-scale neutrino telescope, IceCube, is under construction, alternative plans exist to build even larger detectors that will, however, b e limited by a much higher neutrino energy threshold of 10 PeV or higher rather than 10 to 100 GeV. These future projects detect radio and acoustic pulses as w ell as air showers initiated by ultra-high energy neutrinos. As an alternative, we here propose an expansion of IceCube, using the same strings, placed on a gri d with a spacing of order 500 m. Unlike other proposals, the expanded detector uses methods that are understood and calibrated on atmospheric neutrinos. Atmosp heric neutrinos represent the only background at the energies under consideratio n and is totally negligible. Also, the cost of such a detector is understood. We conclude that supplementing the 81 IceCube strings with a modest number of addi tional strings spaced at large distances can almost double the effective volume of the detector. Doubling the number of strings on a 800 m grid can deliver a d etector that this a factor of 5 larger for horizontal muons at modest cost.Comment: Version to be published in JCA

FCNC in left-right symmetric theories and constraints on the right-handed scale

We revise the limits on the FCNC higgses in manifestly left-right symmetric theories. It is shown that the combination of the Kobayashi-Maskawa CP-violation with the tree level $\Delta S=2$ higgs exchange gives very large contribution to the CP-violating $\epsilon$ parameter. It leads to the new strong constraint on the FCNC higgs mass, M>50- 100 TeV, enhanced by factor of the order $\sqrt{m_t/m_c}$. Being addressed to the supersymmetric left-right models, FCNC problem requires both right-handed scale and supersymmetric mass parameters be heavier than 50 TeV for $tan\beta\sim 1$. The most relaxed case corresponds to $tan\beta\sim 20- 30$ where right-handed scale can be of the order of few TeV.Comment: 11 pages, latex, 3 figure

H3 histamine receptor-mediated activation of protein kinase calpha inhibits the growth of cholangiocarcinoma in vitro and in vivo

Histamine regulates functions via four receptors (HRH1, HRH2, HRH3, and HRH4). The D-myo-inositol 1,4,5-trisphosphate (IP(3))/Ca(2+)/protein kinase C (PKC)/mitogen-activated protein kinase pathway regulates cholangiocarcinoma growth. We evaluated the role of HRH3 in the regulation of cholangiocarcinoma growth. Expression of HRH3 in intrahepatic and extrahepatic cell lines, normal cholangiocytes, and human tissue arrays was measured. In Mz-ChA-1 cells stimulated with (R)-(alpha)-(-)-methylhistamine dihydrobromide (RAMH), we measured (a) cell growth, (b) IP(3) and cyclic AMP levels, and (c) phosphorylation of PKC and mitogen-activated protein kinase isoforms. Localization of PKC alpha was visualized by immunofluorescence in cell smears and immunoblotting for PKC alpha in cytosol and membrane fractions. Following knockdown of PKC alpha, Mz-ChA-1 cells were stimulated with RAMH before evaluating cell growth and extracellular signal-regulated kinase (ERK)-1/2 phosphorylation. In vivo experiments were done in BALB/c nude mice. Mice were treated with saline or RAMH for 44 days and tumor volume was measured. Tumors were excised and evaluated for proliferation, apoptosis, and expression of PKC alpha, vascular endothelial growth factor (VEGF)-A, VEGF-C, VEGF receptor 2, and VEGF receptor 3. HRH3 expression was found in all cells. RAMH inhibited the growth of cholangiocarcinoma cells. RAMH increased IP(3) levels and PKC alpha phosphorylation and decreased ERK1/2 phosphorylation. RAMH induced a shift in the localization of PKC alpha expression from the cytosolic domain into the membrane region of Mz-ChA-1 cells. Silencing of PKC alpha prevented RAMH inhibition of Mz-ChA-1 cell growth and ablated RAMH effects on ERK1/2 phosphorylation. In vivo, RAMH decreased tumor growth and expression of VEGF and its receptors; PKC alpha expression was increased. RAMH inhibits cholangiocarcinoma growth by PKC alpha-dependent ERK1/2 dephosphorylation. Modulation of PKC alpha by histamine receptors may be important in regulating cholangiocarcinoma growth. (Mol Cancer Res 2009;7(10):1704-13

Quantum Time and Spatial Localization: An Analysis of the Hegerfeldt Paradox

Two related problems in relativistic quantum mechanics, the apparent superluminal propagation of initially localized particles and dependence of spatial localization on the motion of the observer, are analyzed in the context of Dirac's theory of constraints. A parametrization invariant formulation is obtained by introducing time and energy operators for the relativistic particle and then treating the Klein-Gordon equation as a constraint. The standard, physical Hilbert space is recovered, via integration over proper time, from an augmented Hilbert space wherein time and energy are dynamical variables. It is shown that the Newton-Wigner position operator, being in this description a constant of motion, acts on states in the augmented space. States with strictly positive energy are non-local in time; consequently, position measurements receive contributions from states representing the particle's position at many times. Apparent superluminal propagation is explained by noting that, as the particle is potentially in the past (or future) of the assumed initial place and time of localization, it has time to propagate to distant regions without exceeding the speed of light. An inequality is proven showing the Hegerfeldt paradox to be completely accounted for by the hypotheses of subluminal propagation from a set of initial space-time points determined by the quantum time distribution arising from the positivity of the system's energy. Spatial localization can nevertheless occur through quantum interference between states representing the particle at different times. The non-locality of the same system to a moving observer is due to Lorentz rotation of spatial axes out of the interference minimum.Comment: This paper is identical to the version appearing in J. Math. Phys. 41; 6093 (Sept. 2000). The published version will be found at http://ojps.aip.org/jmp/. The paper (40 page PDF file) has been completely revised since the last posting to this archiv