single grain grinding an experimental and fem assessment

Abstract Peripheral grinding is inherently complex due to peculiar factors such as: the non deterministic microgeometry of the grinding wheel, the composition of the grinding wheel, essentially non homogeneous, the cutting process dynamics, where the grains' cutting edges operate on a surface whose microgeometry is the result of the cutting actions of the preceding abrasive grains. This paper compares the results of the experimental analysis of the effect of single cutting grains on the actual microgeometry of worked surfaces, and the results obtained by a FEM cutting model where the measured microgeometry of the cutting grains is considered

Modelling Strategy and Parametric Study of Metal Gaskets for Automotive Applications

This paper is focused on finite element simulation of cylinder head gaskets. Finite element codes support several methodologies, each of which has its own strengths and weaknesses. One of the key points lies in the influence of the gasket geometry on its final behaviour. Such a contribution can come from the detailed modelling of the gasket or by defining a global non-linear behaviour in which material and geometry non-linearities are summarised. Two approaches were used to simulate the gasket behaviour. The first one consists in using a 2D approach, which allows to model through-thickness non-linear behaviour of gasket. The second one consists in using conventional 3D finite element modelling. The numerical methods have been discussed and compared in relation to the accordance with experimental data, amount of information supplied and computational time required. Finally, a parametric study shows how some geometric parameters influence the compressive load and the elastic recovery of a single-layer steel gasket

Bearing Health Monitoring Based on the Orthogonal Empirical Mode Decomposition

Bearing is a crucial component of industrial equipment, since any fault occurring in this system usually affects the functionality of the whole machine. To manage this problem, some currently available technologies enable the remote prognosis and diagnosis of bearings, before that faults compromise the system function and safety, respectively. A system for the in-service monitoring of bearing, to detect any inner fault or damage of components and material, allows preventing undesired machine stops. Moreover, it even helps in performing an out-monitoring action, aimed at revealing any anomalous behaviour of the system hosting bearings, through their dynamic response. The in-monitoring can be based on the vibration signal measurement and exploited to detect the presence of defects in material. In this paper, the orthogonal empirical mode decomposition is analysed and tested to investigate how it could be effectively exploited in a lean in-service monitoring operation and remote diagnosis. The proposed approach is validated on a test rig, where an elementary power transmission line was set up. The activity highlights some main properties and practical issues of the technological implementation, as well as the precision of the Orthogonal Empirical Mode Decomposition, as a compact approach for an effective detection of bearing faults in operation

Definition of the cellular interactome of the highly pathogenic avian influenza H5N1 virus: identification of human cellular regulators of viral entry, assembly, and egress.

This study was supported by the Research Fund for the Control of Infectious Diseases, Food and Health Bureau, Hong Kong SAR Government (#09080892), University Grants Committee Area of Excellence Scheme (AoE/M-12/-06), French Ministry of Health, RESPARI Pasteur network, and the Li Ka Shing Foundation

Envelope analysis applied to non-Hertzian contact simulations in damaged roller bearings

In the latest years many researcher focused on the possibility to foresee the failure of a mechanical system in the early stages in order to allow quick response times. Monitoring and diagnostics are at the base of those methodologies of predictive maintenance, which represents the standard for companies. Data acquired by monitoring systems are sometimes not sufficient to perform an effective diagnosis and to detect failures. In the present work the possibility of a defining a relation between the response of a system and the dimension of a defect causing the vibration is explored. Through a non-Hertzian contact model a roller bearing is studied and a correlation is sought between the size of the defect and the frequency content of the contact pressure time history. Resorting to a non-Hertzian approach enables the determination with good accuracy of the overpressures due to edge effects caused by the sudden change in curvature in presence of a defect. The estimation of the pressure variation can be used to estimate the amplitude of the harmonic content exciting the bearing during operation. Using algorithms for the signal analysis already assessed in the literature, in particular the envelope method, an in-depth analysis of the harmonic content of the signal to consider is possible. The possibility of building a correlation between the load and the size of the defect which might help to identify the dimension of a damage from the estimated frequency content. It is then possible to identify the presence and nature of the defect, allowing an early diagnosis of the failure

The M, E, and N structural proteins of the severe acute respiratory syndrome coronavirus are required for efficient assembly, trafficking, and release of virus-like particles

Copyright @ 2008 American Society for Microbiology.The production of virus-like particles (VLPs) constitutes a relevant and safe model to study molecular determinants of virion egress. The minimal requirement for the assembly of VLPs for the coronavirus responsible for severe acute respiratory syndrome in humans (SARS-CoV) is still controversial. Recent studies have shown that SARS-CoV VLP formation depends on either M and E proteins or M and N proteins. Here we show that both E and N proteins must be coexpressed with M protein for the efficient production and release of VLPs by transfected Vero E6 cells. This suggests that the mechanism of SARS-CoV assembly differs from that of other studied coronaviruses, which only require M and E proteins for VLP formation. When coexpressed, the native envelope trimeric S glycoprotein is incorporated onto VLPs. Interestingly, when a fluorescent protein tag is added to the C-terminal end of N or S protein, but not M protein, the chimeric viral proteins can be assembled within VLPs and allow visualization of VLP production and trafficking in living cells by state-of-the-art imaging technologies. Fluorescent VLPs will be used further to investigate the role of cellular machineries during SARS-CoV egress.The University of Hong Kong and the French Ministry of Health