50 research outputs found
Laser-induced degradation and damage morphology in polymer optical fibers
The radiation of pulsed laser systems can generate changes in various materials. On the one hand, these modifications can be used for a variety of applications i.e. laser welding, cutting and many more [1]. The precision and quality depends on the material and laser parameters. On the other hand, material changes are not always desired in other applications. When using optical materials such as optical fibers as a light guide or as a sensor, laser-induced damage effects inside the fiber are to be prevented to ensure constant light guidance and the reliable monitoring of a desired parameter. Therefore, investigations for quality assurance need to be performed. For this reason, this work investigates laserinduced damage in polymer optical fibers (POF) using a nanosecond pulsed laser system at a wavelength of 532 nm. The impact of different laser and fiber parameters on the long-term degradation behavior is observed. In addition, the overall degradation behavior as well as the knowledge gained by analyzing the damage morphology and distribution will be used to obtain a better understanding of the damage mechanisms
Bulk and Boundary Critical Behavior at Lifshitz Points
Lifshitz points are multicritical points at which a disordered phase, a
homogeneous ordered phase, and a modulated ordered phase meet. Their bulk
universality classes are described by natural generalizations of the standard
model. Analyzing these models systematically via modern
field-theoretic renormalization group methods has been a long-standing
challenge ever since their introduction in the middle of the 1970s. We survey
the recent progress made in this direction, discussing results obtained via
dimensionality expansions, how they compare with Monte Carlo results, and open
problems. These advances opened the way towards systematic studies of boundary
critical behavior at -axial Lifshitz points. The possible boundary critical
behavior depends on whether the surface plane is perpendicular to one of the
modulation axes or parallel to all of them. We show that the semi-infinite
field theories representing the corresponding surface universality classes in
these two cases of perpendicular and parallel surface orientation differ
crucially in their Hamiltonian's boundary terms and the implied boundary
conditions, and explain recent results along with our current understanding of
this matter.Comment: Invited contribution to STATPHYS 22, to be published in the
Proceedings of the 22nd International Conference on Statistical Physics
(STATPHYS 22) of the International Union of Pure and Applied Physics (IUPAP),
4--9 July 2004, Bangalore, Indi
Susceptibility amplitude ratio for generic competing systems
We calculate the susceptibility amplitude ratio near a generic higher
character Lifshitz point up to one-loop order. We employ a renormalization
group treatment with independent scaling transformations associated to the
various inequivalent subspaces in the anisotropic case in order to compute the
ratio above and below the critical temperature and demonstrate its
universality. Furthermore, the isotropic results with only one type of
competition axes have also been shown to be universal. We describe how the
simpler situations of -axial Lifshitz points as well as ordinary
(noncompeting) systems can be retrieved from the present framework.Comment: 20 pages, no figure
β-Catenin Signaling Increases during Melanoma Progression and Promotes Tumor Cell Survival and Chemoresistance
Beta-catenin plays an important role in embryogenesis and carcinogenesis by controlling either cadherin-mediated cell adhesion or transcriptional activation of target gene expression. In many types of cancers nuclear translocation of beta-catenin has been observed. Our data indicate that during melanoma progression an increased dependency on the transcriptional function of beta-catenin takes place. Blockade of beta-catenin in metastatic melanoma cell lines efficiently induces apoptosis, inhibits proliferation, migration and invasion in monolayer and 3-dimensional skin reconstructs and decreases chemoresistance. In addition, subcutaneous melanoma growth in SCID mice was almost completely inhibited by an inducible beta-catenin knockdown. In contrast, the survival of benign melanocytes and primary melanoma cell lines was less affected by beta-catenin depletion. However, enhanced expression of beta-catenin in primary melanoma cell lines increased invasive capacity in vitro and tumor growth in the SCID mouse model. These data suggest that beta-catenin is an essential survival factor for metastatic melanoma cells, whereas it is dispensable for the survival of benign melanocytes and primary, non-invasive melanoma cells. Furthermore, beta-catenin increases tumorigenicity of primary melanoma cell lines. The differential requirements for beta-catenin signaling in aggressive melanoma versus benign melanocytic cells make beta-catenin a possible new target in melanoma therapy
On the use of electrochemical multi-sensors in biologically charged media
For the investigation and characterisation of liquid media with
microorganisms, electrochemical sensors are typically used. Usually the
microorganisms are part of the process or cannot be excluded for different
reasons. This paper describes the application of various electrodes, which
are partly miniaturised and combined with multi-sensor systems for several
applications in processes containing microorganisms. The application in
industrial bioprocesses like beer brewing and biogas production, and in paper
manufacturing, is described. The performance of the multi-sensor systems, and
thus their suitability for a contribution to improved process monitoring, is
evaluated. The multi-sensor systems represent an interesting tool to enhance
monitoring capacities at installed systems without the necessity for huge
port installations and offer the possibility to monitor the spatial
distribution of gradients. The developed systems presented here allow
location-independent measurements in process plants with a variable
positioning of the sensors in the industrial reactors