Dynamics of Extreme Black Holes and Massive String States

In a recent paper, Duff and Rahmfeld argued that certain massive $N_R=1/2$ states of the four-dimensional heterotic string correspond to extreme black hole solutions. We provide further, dynamical, evidence for this identification by comparing the scattering of these elementary string states with that of the corresponding extreme black holes, in the limit of low velocities.Comment: 18 pages, harvma

On the Bartnik extension problem for the static vacuum Einstein equations

We develop a framework for understanding the existence of asymptotically flat solutions to the static vacuum Einstein equations with prescribed boundary data consisting of the induced metric and mean curvature on a 2-sphere. A partial existence result is obtained, giving a partial resolution of a conjecture of Bartnik on such static vacuum extensions. The existence and uniqueness of such extensions is closely related to Bartnik's definition of quasi-local mass.Comment: 33 pages, 1 figure. Minor revision of v2. Final version, to appear in Class. Quantum Gravit

More on Four-Dimensional Extremal Black Holes

We consider an embedding of the extremal four-dimensional Reissner-Nordstr\"om black hole into type $IIB$ string theory. The equivalent type $IIB$ configuration, in the D-brane weak-coupling picture, is a bound state of D1- and D5-branes threaded by fundamental type $IIB$ strings. The bound state involves also a NSNS solitonic 5-brane, mimicking the role of the Kaluza-Klein magnetic monopole. The statistical entropy derived by counting the degeneracy of the BPS-saturated excitations of this bound state agrees perfectly with the (semiclassical) Bekenstein-Hawking formula.Comment: 19 pages, using Latex, no figure

Monopoles and Instantons in String Theory

In recent work, several classes of solitonic solutions of string theory with higher-membrane structure have been obtained. These solutions can be classified according to the symmetry possessed by the solitons in the subspace of the spacetime transverse to the membrane. Solitons with four-dimensional spherical symmetry represent instanton solutions in string theory, while those with three-dimensional spherical symmetry represent magnetic monopole-type solutions. For both of these classes, we discuss bosonic as well as heterotic solutions.Comment: 16 page

Some Remarks on Effective Range Formula in Potential Scattering

In this paper, we present different proofs of very recent results on the necessary as well as sufficient conditions on the decrease of the potential at infinity for the validity of effective range formulas in 3-D in low energy potential scattering (Andr\'e Martin, private communication, to appear. See Theorem 1 below). Our proofs are based on compact formulas for the phase-shifts. The sufficiency conditions are well-known since long. But the necessity of the same conditions for potentials keeping a constant sign at large distances are new. All these conditions are established here for dimension 3 and for all angular momenta $\ell \geq 0$

Curcumin induces apoptosis of upper aerodigestive tract cancer cells by targeting multiple pathways

Curcumin, a natural compound isolated from the Indian spice Haldi or curry powder , has been used for centuries as a traditional remedy for many ailments. Recently, the potential use of curcumin in cancer prevention and therapy urges studies to uncover the molecular mechanisms associated with its anti-tumor effects. In the current manuscript, we investigated the mechanism of curcumin-induced apoptosis in upper aerodigestive tract cancer cell lines and showed that curcumin-induced apoptosis is mediated by the modulation of multiple pathways such as induction of p73, and inhibition of p-AKT and Bcl-2. Treatment of cells with curcumin induced both p53 and the related protein p73 in head and neck and lung cancer cell lines. Inactivation of p73 by dominant negative p73 significantly protected cells from curcumin-induced apoptosis, whereas ablation of p53 by shRNA had no effect. Curcumin treatment also strongly inhibited p-AKT and Bcl-2 and overexpression of constitutively active AKT or Bcl-2 significantly inhibited curcumin-induced apoptosis. Taken together, our findings suggest that curcumin-induced apoptosis is mediated via activating tumor suppressor p73 and inhibiting p-AKT and Bcl-2

Total Widths And Slopes From Complex Regge Trajectories

Maximally complex Regge trajectories are introduced for which both Re $\alpha(s)$ and Im $\alpha(s)$ grow as $s^{1-\epsilon}$ ($\epsilon$ small and positive). Our expression reduces to the standard real linear form as the imaginary part (proportional to $\epsilon$) goes to zero. A scaling formula for the total widths emerges: $\Gamma_{TOT}/M\to$ constant for large M, in very good agreement with data for mesons and baryons. The unitarity corrections also enhance the space-like slopes from their time-like values, thereby resolving an old problem with the $\rho$ trajectory in $\pi N$ charge exchange. Finally, the unitarily enhanced intercept, $\alpha_{\rho}\approx 0.525$, \nolinebreak is in good accord with the Donnachie-Landshoff total cross section analysis.Comment: 9 pages, 3 Figure

Nucleation of PP-Branes and Fundamental Strings

We construct a solution to the low-energy string equations of motion in five dimensions that describes a circular loop of fundamental string exponentially expanding in a background electric $H$-field. Euclideanising this gives an instanton for the creation of a loop of fundamental string in a background $H$-field, and we calculate the rate of nucleation. Solutions describing magnetically charged strings and $p$-branes, where the gauge field comes from Kaluza-Klein reduction on a circle, are also constructed. It is known that a magnetic flux tube in four (reduced) spacetime dimensions is unstable to the pair creation of Kaluza-Klein monopoles. We show that in $(4+p)$ dimensions, magnetic $(p+1)$ ``fluxbranes" are unstable to the nucleation of a magnetically charged spherical $p$-brane. In ten dimensions the instanton describes the nucleation of a Ramond-Ramond magnetically charged six-brane in type IIA string theory. We also find static solutions describing spherical charged $p$-branes or fundamental strings held in unstable equilibrium in appropriate background fields. Instabilities of intersecting magnetic fluxbranes are also discussed.Comment: 28 pages, harvmac (b), reference added, typos correcte

A compactness theorem for scalar-flat metrics on manifolds with boundary

Let (M,g) be a compact Riemannian manifold with boundary. This paper is concerned with the set of scalar-flat metrics which are in the conformal class of g and have the boundary as a constant mean curvature hypersurface. We prove that this set is compact for dimensions greater than or equal to 7 under the generic condition that the trace-free 2nd fundamental form of the boundary is nonzero everywhere.Comment: 49 pages. Final version, to appear in Calc. Var. Partial Differential Equation