4,845 research outputs found

    Active Learning for Active Minds: A Conversation with Learning Leaders

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    17 USC 105 interim-entered record; under review.The article of record as published may be found at https://cimsec.org/active-learning-for-active-minds-a-conversation-with-learning-leaders/U.S. Government affiliation is unstated in article text

    Vitrification: Fundamental Principles and Its Application for Cryopreservation of Human Reproductive Cells

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    The fundamental understanding of cryobiology through experimentation in the 1960s, 1970s, and 1980s has led to the development of today’s vitrification technology. Although human embryo and oocyte vitrification was slow to evolve, it has become an invaluable technology in the field of reproductive medicine. The aim of this chapter is to discuss some of the underlying basic principles behind forming a metastable glass phase during rapid cooling in liquid nitrogen (LN2) and the prevention of recrystallization events upon warming. We then highlight how this understanding has led to its highly effective and reliable usage in clinical IVF. Furthermore, we describe how quality control factors (e.g., ease of use, repeatability, reliability, labeling security, and cryostorage safety) can vary between vitrification device systems, potentially influencing clinical outcomes and creating possible liability issues. An open-minded approach to continued experimentation is a necessity, especially pertaining to oocyte freeze preservation, if we are to optimize the vitrification of reproductive cells and tissue in the future

    Cutline: 1981-82 scholarship winner - Ronan

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    Background: Self-management support has been shown to improve clinical outcomes. Health coaching, one form of self-management support, empowers patients within the health care system by providing information and through collaboratively developed care plans. Purpose: Assess the impact of The Lifestyle Initiative, a coaching-based health program utilized by Aurora Health Care caregivers or family members. Methods: The Lifestyle Initiative is a coaching-based approach for Aurora caregivers or family members enrolled in Aurora’s health insurance network. Individuals were recruited from the care management database, and all participants had an Aurora primary care provider. Participation was limited to those ≥ 18 years of age who had a diagnosis of type 2 diabetes or hypertension (or both), had glycated hemoglobin (A1c) ≤ 8.0, and were not on insulin. The Lifestyle Initiative was rolled out in three phases. Phase I: health coaching sessions through a standard web- and app-based platform (Noom Health), and access to a stress-management program (HeartMath). Phase II: health coaching sessions through a standard web- and app-based platform co-created by Aurora’s Department of Integrative Medicine and Noom Health, and access to HeartMath; Phase III: health coaching sessions through a standard web- and app-based platform (Noom Health), and a customized web- and app-based platform. Those enrolled in each phase acted as their own controls. Paired t-tests were used to compare pre- and postintervention results of each phase. Results: The majority of Phase I participants (n = 23; mean age 54.4 years) were female (91.3%) and white (52.2%). Preintervention A1c and blood pressure were not statistically different postintervention. However, pre- vs postintervention weights were statistically different (228.2 vs 218.5 lb; P \u3c 0.01), as well as pre- vs postintervention body mass index (37.3 vs 35.7 kg/m2; P \u3c 0.01). The majority of Phase II participants (n = 63; mean age 54.8 years) also were female (81.0%) and white (88.9%). Pre- and postintervention blood pressures were not statistically different. However, pre- vs postintervention A1c (7.2 vs 6.6; P \u3c 0.02), weights (229.6 vs 225.7 lb; P \u3c 0.05), and body mass index (37.1 vs 36.5 kg/m2; P \u3c 0.05) were statistically improved. Phase III data collection is underway. Conclusion: The Lifestyle Initiative health coaching program significantly improves certain health metrics when applied to health system employees and family members with diabetes or hypertension. Further study is needed to explore sustainability and the effects of more robust programs

    The \u3ci\u3eLeucaena\u3c/i\u3e Network: A Grazier Advocacy Organisation Ensuring the Future of a Valuable Forage Resource for Northern Australia

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    Leucaena leucocephala is a productive and sustainable forage tree legume for beef cattle production in northern Australia. Following a protracted period of research and development to overcome agronomic and social constraints, substantial adoption by graziers is now occurring (Mullen, these proceedings). However, a recent challenge has threatened future development, viz. the perception by some environmentalists that leucaena is an environmental weed. In addition, production-oriented support from public research and development organisations has diminished significantly over the past 20 years. The Leucaena Network (TLN) was formed in July 2000, primarily to counter the anti-leucaena movement, but has since developed as an advocacy organisation promoting the many beneficial aspects of leucaena forage systems. The structure, aims and achievements of this unique organisation are outlined below

    Psyllid Resistance in the Leucaena Genus

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    Leucaena species varied from highly susceptible to highly resistant in their response to the psyllid insect (Heteropsylla cubana) at 2 sites, a high psyllid environment at Brisbane, Australia and a moderate psyllid environment at Los Baños, Philippines. L. leucocephala was the most susceptible species. There was considerable intraspecific variation in psyllid resistance within L. collinsii, L. diversifolia and L. pallida. Plant reponse to psyllid challenge between environments was highly correlated but not linear. The higher psyllid challenge environment at Brisbane permitted greater discrimination between species and fewer Leucaena species were ranked as psyllid resistant

    Theory of Activated Transport in Bilayer Quantum Hall Systems

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    We analyze the transport properties of bilayer quantum Hall systems at total filling factor ν=1\nu=1 in drag geometries as a function of interlayer bias, in the limit where the disorder is sufficiently strong to unbind meron-antimeron pairs, the charged topological defects of the system. We compute the typical energy barrier for these objects to cross incompressible regions within the disordered system using a Hartree-Fock approach, and show how this leads to multiple activation energies when the system is biased. We then demonstrate using a bosonic Chern-Simons theory that in drag geometries, current in a single layer directly leads to forces on only two of the four types of merons, inducing dissipation only in the drive layer. Dissipation in the drag layer results from interactions among the merons, resulting in very different temperature dependences for the drag and drive layers, in qualitative agreement with experiment.Comment: 4 pages, 2 figure
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