Kinds of Self-Knowledge in Ancient Thought

This chapter explores the topic of self-knowledge in ancient thought, asking in particular what the ancient concept (or concepts) of knowing oneself amounts to. The chapter begins by contrasting the issues which occupy ancient and contemporary discussions of self-knowledge, and the obvious points of continuity and discontinuity between the two. The author isolates two forms of self-knowledge: cognitive self-knowledge or knowledge of one’s own mental states, and dispositional self-knowledge or knowledge of one’s moral or intellectual dispositions, and traces the treatment of these forms of self-knowledge in the works of Plato, Aristotle, Hellenistic philosophers, and Plotinus. In the course of discussing the texts of each thinker or school, and the relevant scholarship, this chapter also canvasses the ways in which the chapters in the rest of this volume seek to engage with some of the problems or issues that have emerged

Says Who? Modes of Speaking in the Euthydemus

With very few exceptions, the relatively small number of scholars who have lavished attention on Plato’s Euthydemus have found it fertile soil in two respects. For some, it is a compilation of fallacies committed by the sophistic brothers, Euthydemus and Dionysodorus, designed to serve as an introductory sourcebook of bad argument—a forerunner to Aristotle’s Sophistici Elenchi [Robinson 1942; Sprague 1962; Hawtrey 1981]. 1 For others, it contains a significant contribution to Platonic ethics by way of a compressed and vexing argument for the view that compared to other purported goods (e.g., health and wealth), wisdom is the only good ‘in itself’ (280b–282a) (e.g. Irwin [1995: 32–3, 73n, 118–20]; Russell [2005: 16–47]). 2 By contrast, in her various papers and lectures on the Euthydemus, M.M. McCabe discerns a much wider variety of topics at issue in the dialogue (e.g., self-knowledge, a rejection of consequentialism), and while focusing on specific passages, has situated her interpretations within a view of the text as a whole. 3 So, too, in the target paper for this volume, ‘First Chop Your Logos … Socrates and the Sophists on Logic, Language, and Development’, McCabe [2021a] argues that a close reading of several passages reveals the sophistic brothers’ deployment of a formidable position or view on the relation of language to the world that presents a serious challenge to Socrates’ assumptions about statements and saying, and that Plato’s response to the challenge emerges from consideration of different elements at play throughout the whole dialogue. Due to limited space, I will restrict myself in this introduction to a sketch of the structure of the Euthydemus, for those unfamiliar with it, and an outline of McCabe’s reading of the sophistic challenge and Plato’s response to it, occasionally gesturing towards key claims or objections advanced in the commentaries in this volume (though I have generally been unable to note McCabe’s [2021b] detailed responses in her reply piece, ‘Who’s Who and What’s What’)

Aging Out of the Foster Care System to Adulthood: Findings, Challenges, and Recommendations

To assess and ultimately help meet the needs of youth who age out of foster care in the United States, the Joint Center Health Policy Institute (JCHPI) -- with support from the Robert Wood Johnson Foundation and in partnership with the Black Administrators in Child Welfare Inc. (BACW) -- conducted reconnaissance on the unmet needs of these youth. This project was undertaken to guide the Robert Wood Johnson Foundation in thinking about steps they might take to help meet the needs of youth who age out of foster care in this country. Conducting a literature review, a telephone survey, and listening sessions enabled us to develop insights into the workings of the foster care system and the experiences of youth while in the system and when aging out of it

Wavelength Scanning Interferometry for PV Production In-line Metrology

Flexible PV modules are manufactured using roll to roll (R2R) technology. These modules require a flexible barrier material to prevent water vapor ingress

Corrigendum: an overview of MicroRNAs as biomarkers of ALS

A Corrigendum on An Overview of MicroRNAs as Biomarkers of ALS by Joilin, G., Leigh, P. N., Newbury, S. F., and Hafezparast, M. (2019). Front. Neurol. 10:186. doi: 10.3389/fneur.2019.00186 In the original article, there was a mistake in Table 1 as published. Some of the miRNAs listed in the table were incorrectly placed in the wrong column and/or row. The authors apologize for this error and state that this does not change the scientific conclusions of the article in any way. The original article has been updated

The interaction between HIV and other sexually transmitted infections in South Africa: a model-based evaluation

Includes bibliographical references.Sexually transmitted infections (STIs) have been shown to increase the probability of HIV transmission, but there remains much uncertainty regarding the role of STI treatment in HIV prevention. This thesis aims to develop a mathematical model to estimate the prevalence of STIs in South Africa, the contribution of STIs to the spread of HIV, and the effects of changes in sexual behaviour and changes in STI treatment. A deterministic model is developed to simulate the transmission of HIV and six other STIs (syphilis, genital herpes, chancroid, gonorrhoea, chlamydial infection and trichomoniasis), as well as the incidence of bacterial vaginosis and vaginal candidiasis in women. The model is fitted to national HIV prevalence survey data, STI prevalence data from sentinel surveys and data from sexual behaviour surveys, using Bayesian techniques. Model results suggest that South Africa has some of the highest STI prevalence levels in the world, but that certain STIs – notably syphilis, chancroid, gonorrhoea and trichomoniasis – have declined in prevalence since the mid-1990s, following the introduction of syndromic management programmes and increases in condom use. STIs account for more than half of new HIV infections, and genital herpes is the most significant STI promoting the transmission of HIV. Syndromic management programmes reduced HIV incidence in South Africa by 3-10% over the decade following their introduction (1994-2004). Further reductions in HIV incidence could be achieved by promoting patient-initiated treatment of genital herpes, by addressing rising levels of drug resistance in gonococcal isolates, and by encouraging prompt health seeking for STIs. Concurrent partnerships are a major factor driving HIV transmission, accounting for 74-87% of new HIV infections over the 1990-2000 period. Halving unprotected sex in non-spousal relationships would reduce HIV incidence over the 2010 -2020 period by 32-43%. This thesis contributes to the understanding of HIV/AIDS epidemiology in South Africa by quantifying the contribution of various behavioural and biological factors to HIV transmission. This thesis also high lights several opportunities for reducing the future incidence of HIV. In addition, this thesis advances the assessment of uncertainty in STI models by proposing a Bayesian approach to incorporating sexual behaviour data and STI prevalence data into the parameter estimation proces

Intelligent modelling of bioprocesses: A comparison of structured and unstructured approaches

This contribution moves in the direction of answering some general questions about the most effective and useful ways of modelling bioprocesses. We investigate the characteristics of models that are good at extrapolating. We trained 3 fully predictive models with different representational structures (diff eqns, inheritance of rates, network of reactions) on Saccharopolyspora erythraea shake flask fermentation data using genetic programming. The models were then tested on unseen data outside the range of the training data and the resulting performances compared. It was found that constrained models with mathematical forms analogous to internal mass balancing and stoichiometric were superior to flexible unconstrained models even though no A priori knowledge of this fermentation was used

A new view of body image : a school-based participatory action research project with young Aboriginal women

Research continues to suggest that young women experience body image concerns; nevertheless, the majority of this body image research has focused on white women, and the experiences of young Aboriginal women have typically been overlooked. When research has included Aboriginal women, it has generally been quantitative in nature (e.g., Gittelsohn et al., 1996; Marchessault, 2004; Story et al., 1995) and has highlighted body dissatisfaction that is equal to and even greater than that experienced by white women. Despite the alarming statistics suggesting that body image concerns are common among Aboriginal women, few researchers have engaged young Aboriginal women in qualitative research projects that seek to highlight their unique experiences. My previous research with young Aboriginal women (i.e., Fleming et al., 2006; McHugh & Kowalski, in press) are some of the first Canadian studies to have an exclusive focus on Aboriginal women’s body image experiences. This research suggested that young Aboriginal women’s body image experiences may not be as negative as previous quantitative research has suggested, but highlighted the need to work with young women to develop strategies for positively managing body image experiences. Therefore, the purpose of this research was to engage in a collaborative, school-based participatory action research (PAR) project in partnership with a local high school to provide young women, primarily young Aboriginal women, with an opportunity to manage their body image experiences in an effective manner. Students, teachers, and staff of Nutana Collegiate participated in this project, which took place over a 10-month period from September 2006 to June 2007. All Nutana school members were welcomed to participate and many took part in the various action initiatives that were developed. A group of seven young Aboriginal women formed a core group of participants who were primarily responsible for the development and implementation of most action initiatives. A five phase PAR model, which was based on the work of Stringer and Genat (2004), was proposed as the methodological framework for this project. However, given the emergent and dynamic nature of PAR processes, and the unique features of the school community, the manner in which the project actually unfolded was quite different from the original plan. This project ultimately had two phases, the Relationship Building Phase and the Action Phase. In an effort to develop relationships with school community members, during the Relationship Building phase I engaged in the three general processes of: familiarization, making connections, and giving back to the school. My commitment to these processes supported my initial goal to develop trusting relationships with community members, which subsequently formed a strong foundation for the development of effective and successful action initiatives. Eight action initiatives, which were represented by three themes, were developed and implemented as part of the Action phase. The three themes were: (1) Promoting Positive Body Image Experiences, (2) Self-Expression, and (3) Creating Awareness. The development and implementation of action at various levels (i.e., individual, school, provincial, and national) was the most significant outcome of this research. The success and relevance of the various action initiatives was demonstrated by the words of the participants, the overall support of various school members, and the commitment of the core group to the goals of this PAR project. Although there were methodological challenges and considerations that needed to be navigated throughout this PAR project, findings from this research suggest that universities and local high schools can and should work together to develop school-based body image programs for young Aboriginal women. As well, and maybe most importantly, this research highlights the strength of using PAR methodologies when engaging young Aboriginal women in body image research