273 research outputs found
Nonlinear Impurity Modes in Homogeneous and Periodic Media
We analyze the existence and stability of nonlinear localized waves described
by the Kronig-Penney model with a nonlinear impurity. We study the properties
of such waves in a homogeneous medium, and then analyze new effects introduced
by periodicity of the medium parameters. In particular, we demonstrate the
existence of a novel type of stable nonlinear band-gap localized states, and
also reveal an important physical mechanism of the oscillatory wave
instabilities associated with the band-gap wave resonances.Comment: 11 pages, 3 figures; To be published in: Proceedings of the NATO
Advanced Research Workshop "Nonlinearity and Disorder: Theory and
Applications" (Tashkent, 2-6 Oct, 2000) Editors: P.L. Christiansen and F.K.
Abdullaev (Kluwer, 2001
On the fluctuations of jamming coverage upon random sequential adsorption on homogeneous and heterogeneous media
The fluctuations of the jamming coverage upon Random Sequential Adsorption
(RSA) are studied using both analytical and numerical techniques. Our main
result shows that these fluctuations (characterized by )
decay with the lattice size according to the power-law . The exponent depends on the dimensionality of
the substrate and the fractal dimension of the set where the RSA process
actually takes place () according to .This
theoretical result is confirmed by means of extensive numerical simulations
applied to the RSA of dimers on homogeneous and stochastic fractal substrates.
Furthermore, our predictions are in excellent agreement with different previous
numerical results.
It is also shown that, studying correlated stochastic processes, one can
define various fluctuating quantities designed to capture either the underlying
physics of individual processes or that of the whole system. So, subtle
differences in the definitions may lead to dramatically different physical
interpretations of the results. Here, this statement is demonstrated for the
case of RSA of dimers on binary alloys.Comment: 20 pages, 8 figure
Influence of Coulomb and Phonon Interaction on the Exciton Formation Dynamics in Semiconductor Heterostructures
A microscopic theory is developed to analyze the dynamics of exciton
formation out of incoherent carriers in semiconductor heterostructures. The
carrier Coulomb and phonon interaction is included consistently. A cluster
expansion method is used to systematically truncate the hierarchy problem. By
including all correlations up to the four-point (i.e. two-particle) level, the
fundamental fermionic substructure of excitons is fully included. The analysis
shows that the exciton formation is an intricate process where Coulomb
correlations rapidly build up on a picosecond time scale while phonon dynamics
leads to true exciton formation on a slow nanosecond time scale.Comment: 18 pages, 7 figure
Nonlinear localized waves in a periodic medium
We analyze the existence and stability of nonlinear localized waves in a
periodic medium described by the Kronig-Penney model with a nonlinear defect.
We demonstrate the existence of a novel type of stable nonlinear band-gap
localized states, and also reveal an important physical mechanism of the
oscillatory wave instabilities associated with the band-gap resonances.Comment: 4 pages, 5 figure
Quantitative ultrasound spectroscopy for screening cylindrical lithium-ion batteries for second-life applications
Diagnosing lithium-ion battery degradation is a crucial part of managing energy storage systems. Recent research has explored ultrasonic testing for non-invasive health assessment as an alternative to traditional, time-consuming, electrical-only methods. Assessing the state of health is vital for determining quality at end of ‘first’ life, with retired batteries at 70–80 % health still holding value for secondlife applications. Over the coming years, tens of GWh of salvaged batteries will hit the market, requiring rapid noninvasive methods to classify retired batteries according to their state of health. This study uses a 64 – element ultrasonic array to obtain mid-band quantitative ultrasound spectroscopy parameters – including mid-band fit, spectral slope, and intercept – from circumferential waves around cylindrical batteries. Thirteen cylindrical cells were used to evaluate the methodology: three pristine and ten retired from the same source. The mid-band fit showed the ability to track the state of charge and discriminate between the state of health levels in accelerated degradation experiments both with pristine batteries, and also with recovered secondlife batteries with unknown historical use. Linear-array ultrasonic transducers, coupled with quantitative spectral parameters, show promise for future non-destructive battery health screening methods, offering valuable insights for the emerging used battery market
Cell-in-cell phenomenon: leukocyte engulfment by non-tumorigenic cells and cancer cell lines
Background
Research on cell-in-cell (CIC) phenomena, including entosis, emperipolesis and cannibalism, and their biological implications has increased in recent years. Homotypic and heterotypic engulfment of various target cells by numerous types of host cells has been studied in vitro and in tissue sections. This work has identified proteins involved in the mechanism and uncovered evidence for CIC as a potential histopathologic predictive and prognostic marker in cancer. Our experimental study focused on non-professional phagocytosis of leukocytes.
Results
We studied the engulfment of peripheral blood mononuclear cells isolated from healthy donors by counting CIC structures. Two non-tumorigenic cell lines (BEAS-2B, SBLF-9) and two tumour cell lines (BxPC3, ICNI) served as host cells. Immune cells were live-stained and either directly co-incubated or treated with irradiation or with conventional or microwave hyperthermia. Prior to co-incubation, we determined leukocyte viability for each batch via Annexin V-FITC/propidium iodide staining.
All host cells engulfed their targets, with uptake rates ranging from 1.0% ± 0.5% in BxPC3 to 8.1% ± 5.0% in BEAS-2B. Engulfment rates of the cancer cell lines BxPC3 and ICNI (1.6% ± 0.2%) were similar to those of the primary fibroblasts SBLF-9 (1.4% ± 0.2%). We found a significant negative correlation between leukocyte viability and cell-in-cell formation rates. The engulfment rate rose when we increased the dose of radiotherapy and prolonged the impact time. Further, microwave hyperthermia induced higher leukocyte uptake than conventional hyperthermia.
Using fluorescent immunocytochemistry to descriptively study the proteins involved, we detected ring-like formations of diverse proteins around the leukocytes, consisting, among others, of α-tubulin, integrin, myosin, F-actin, and vinculin. These results suggest the involvement of actomyosin contraction, cell-cell adhesion, and the α-tubulin cytoskeleton in the engulfment process.
Conclusions
Both non-tumorigenic and cancer cells can form heterotypic CIC structures by engulfing leukocytes. Decreased viability and changes caused by microwave and X-ray irradiation trigger non-professional phagocytosis
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