64 research outputs found
Bullous Pemphigoid, Herpes Gestationis and Linear Dermatitis Herpetiformis: Circulating Anti-Basement Membrane Zone Antibodies; in Vitro Studies
It is well established that suprabasal acantholysis can be produced in tissue culture of normal human skin in the presence of pemphigus IgG autoantibody. In this study, bullous pemphigoid, herpes gestationis and linear dermatitis herpetiformis anti-basement membrane zone antibodies failed to produce dermoepidermal separation in a tissue culture model in spite of the presence of complement. The binding of the antibodies was demonstrated by immunofluorescence and immunoelectron microscopy; ultrastructurally, identical binding sites of anti-basement membrane zone antibodies could be demonstrated in vitro, as has been observed in vivo previously. Tissue culture is a suitable model for studying the binding sites of circulating anti-basement membrane zone antibodies but the functional activity (blister formation) of these antibodies cannot be assessed thereby
Herausforderung Employ ability: Zukunftsfähiges Gesundheitsmanagement am Beispiel der E.ON Ruhrgas AG
ERYTHROPOIETIC PROTOPORPHYRIA: SUBMICROSCOPIC EVENTS DURING THE ACUTE PHOTOSENSITIVITY FLARE
Failure to Detect Gliadin or Gliadin Binding Sites in the Skin of Patients with Dermatitis Herpetiformis: Immunofluorescence, Organ Culture and Autoradiographic Studies
Protective action of beta-carotene against lethal photosensitization of fibroblasts in vitro*
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