Scattering of slow-light gap solitons with charges in a two-level medium

The Maxwell-Bloch system describes a quantum two-level medium interacting with a classical electromagnetic field by mediation of the the population density. This population density variation is a purely quantum effect which is actually at the very origin of nonlinearity. The resulting nonlinear coupling possesses particularly interesting consequences at the resonance (when the frequency of the excitation is close to the transition frequency of the two-level medium) as e.g. slow-light gap solitons that result from the nonlinear instability of the evanescent wave at the boundary. As nonlinearity couples the different polarizations of the electromagnetic field, the slow-light gap soliton is shown to experience effective scattering whith charges in the medium, allowing it for instance to be trapped or reflected. This scattering process is understood qualitatively as being governed by a nonlinear Schroedinger model in an external potential related to the charges (the electrostatic permanent background component of the field).Comment: RevTex, 14 pages with 5 figures, to appear in J. Phys. A: Math. Theo

The effects of Δ9-tetrahydrocannabinol on the dopamine system

Δ(9)-tetrahydrocannabinol (THC), the main psychoactive ingredient in cannabis, is a pressing concern to global mental health. Patterns of use are changing drastically due to legalisation, availability of synthetic analogues (‘spice’), cannavaping and aggrandizements in the purported therapeutic effects of cannabis. Many of THC’s reinforcing effects are mediated by the dopamine system. Due to complex cannabinoid-dopamine interactions there is conflicting evidence from human and animal research fields. Acute THC causes increased dopamine release and neuron activity, whilst long-term use is associated with blunting of the dopamine system. Future research must examine the long-term and developmental dopaminergic effects of the drug

Cortisol, cognition and the ageing prefrontal cortex

The structural and functional decline of the ageing human brain varies by brain region, cognitive function and individual. The underlying biological mechanisms are poorly understood. One potentially important mechanism is exposure to glucocorticoids (GCs; cortisol in humans); GC production is increasingly varied with age in humans, and chronic exposure to high levels is hypothesised to result in cognitive decline via cerebral remodelling. However, studies of GC exposure in humans are scarce and methodological differences confound cross-study comparison. Furthermore, there has been little focus on the effects of GCs on the frontal lobes and key white matter tracts in the ageing brain. This thesis therefore examines relationships among cortisol levels, structural brain measures and cognitive performance in 90 healthy, elderly community-dwelling males from the Lothian Birth Cohort 1936. Salivary cortisol samples characterised diurnal (morning and evening) and reactive profiles (before and after a cognitive test battery). Structural variables comprised Diffusion Tensor Imaging measures of major brain tracts and a novel manual parcellation method for the frontal lobes. The latter was based on a systematic review of current manual methods in the context of putative function and cytoarchitecture. Manual frontal lobe brain parcellation conferred greater spatial and volumetric accuracy when compared to both single- and multi-atlas parcellation at the lobar level. Cognitive ability was assessed via tests of general cognitive ability, and neuropsychological tests thought to show differential sensitivity to the integrity of frontal lobe sub-regions. The majority of, but not all frontal lobe test scores shared considerable overlap with general cognitive ability, and cognitive scores correlated most consistently with the volumes of the anterior cingulate. This is discussed in light of the diverse connective profile of the cingulate and a need to integrate information over more diffuse cognitive networks according to proposed de-differentiation or compensation in ageing. Individuals with higher morning, evening or pre-test cortisol levels showed consistently negative relationships with specific regional volumes and tract integrity. Participants whose cortisol levels increased between the start and end of cognitive testing showed selectively larger regional volumes and lower tract diffusivity (correlation magnitudes <.44). The significant relationships between cortisol levels and cognition indicated that flatter diurnal slopes or higher pre-test levels related to poorer test performance. In contrast, higher levels in the morning generally correlated with better scores (correlation magnitudes <.25). Interpretation of all findings was moderated by sensitivity to type I error, given the large number of comparisons conducted. Though there were limited candidates for mediation analysis, cortisol-function relationships were partially mediated by tract integrity (but not sub-regional frontal volumes) for memory and post-error slowing. This thesis offers a novel perspective on the complex interplay among glucocorticoids, cognition and the structure of the ageing brain. The findings suggest some role for cortisol exposure in determining age-related decline in complex cognition, mediated via brain structure

Effets de longueur d'un amplificateur optique à semiconducteur sur la dynamique de gain

On montre qu'en configuration co et contra-propagative, la longueur de l'amplificateur optique à semiconducteur modifie la dynamique de gain. Le surgain est plus important lorsque la longueur augmente et les temps de dynamique de gain varient fortement

Periodic waves and solitons of two-photon propagation

We study the two-photon propagation (TPP) modelling equations. The one-phase periodic solutions are obtained in an effective form. Their modulation is investigated by means of the Whitham method. The theory developed is applied to the problem of creation of TPP solitons on the sharp front of a long pulse

Enseñanza de las ciencias : revista de investigación y experiencias didácticas

Resumen basado en el de la publicaciónTítulo, resumen y palabras clave también en inglésSe presentan las características generales de los modelos basados en el individuo (IbM) y la manera de tratar con ellos cuando se modeliza un biosistema o conjunto de entidades discretas con vida propia que evolucionan en un entorno cambiante. Se presenta una discusión de las ventajas e inconvenientes que presenta este tipo de modelización discreta frente a la modelización continua más clásica. Se expone el protocolo específico recientemente aceptado para presentar y comunicar IbM, y se identifica la plataforma NetLogo, de uso público y libre, accesible desde la web, como adecuada para la implementación de este tipo de modelo computacional. Con todo ello se constata el interés de introducir IbMs en la docencia para trabajar y practicar con la competencia en modelización.ES