27 research outputs found
Mathematical models in landscape ecology: stability analysis and numerical tests
Si presentano vari modelli matematici per la valutazione della qualita' ecologica di un sistema ambientale. Si presenta poi un nuovo modello denominato PANDORA 2.0 e si mostra un'applicazione nel territorio della provincia di Viterb
Hipk2 cooperates with p53 to suppress γ-ray radiation-induced mouse thymic lymphoma
A genome-wide screen for genetic alterations in radiation-induced thymic lymphomas generated from p53+/− and p53−/− mice showed frequent loss of heterozygosity (LOH) on chromosome 6. Fine mapping of these LOH regions revealed three non-overlapping regions, one of which was refined to a 0.2 Mb interval that contained only the gene encoding homeobox-interacting protein kinase 2 (Hipk2). More than 30% of radiation-induced tumors from both p53+/− and p53−/− mice showed heterozygous loss of one Hipk2 allele. Mice carrying a single inactive allele of Hipk2 in the germline were susceptible to induction of tumors by γ-radiation, but most tumors retained and expressed the wild-type allele, suggesting that Hipk2 is a haploinsufficient tumor suppressor gene for mouse lymphoma development. Heterozygous loss of both Hipk2 and p53 confers strong sensitization to radiation-induced lymphoma. We conclude that Hipk2 is a haploinsufficient lymphoma suppressor gene
Technical Design Report EuroGammaS proposal for the ELI-NP Gamma beam System
The machine described in this document is an advanced Source of up to 20 MeV
Gamma Rays based on Compton back-scattering, i.e. collision of an intense high
power laser beam and a high brightness electron beam with maximum kinetic
energy of about 720 MeV. Fully equipped with collimation and characterization
systems, in order to generate, form and fully measure the physical
characteristics of the produced Gamma Ray beam. The quality, i.e. phase space
density, of the two colliding beams will be such that the emitted Gamma ray
beam is characterized by energy tunability, spectral density, bandwidth,
polarization, divergence and brilliance compatible with the requested
performances of the ELI-NP user facility, to be built in Romania as the Nuclear
Physics oriented Pillar of the European Extreme Light Infrastructure. This
document illustrates the Technical Design finally produced by the EuroGammaS
Collaboration, after a thorough investigation of the machine expected
performances within the constraints imposed by the ELI-NP tender for the Gamma
Beam System (ELI-NP-GBS), in terms of available budget, deadlines for machine
completion and performance achievement, compatibility with lay-out and
characteristics of the planned civil engineering
A simulation method for the stability analysis of landscape scenarios by using NetLogo application inn GIS environment
A procedure for mathematical analysis of landscape evolution and equilibrium scenarios assessment
The present research has been partially supported by the National Group GNFM of INdA
A procedure for mathematical analysis of landscape evolution and equilibrium scenarios assessment
The present research has been partially supported by the National Group GNFM of INdA