Identification and Structural Characterization of a New Three-Finger Toxin Hemachatoxin from Hemachatus haemachatus Venom

10.1371/journal.pone.0048112PLoS ONE710

Change in growth velocity during the first year of GH treatment in the 240 SGA children according to the dose of rhGH: high dose 0·43 ± 0·17 mg/kg/week; low dose 0·21 ± 0·04 mg/kg/week

<p><b>Copyright information:</b></p><p>Taken from "GH responsiveness in a large multinational cohort of SGA children with short stature (NESTEGG) is related to the exon 3 GHR polymorphism"</p><p></p><p>Clinical Endocrinology 2007;67(3):457-461.</p><p>Published online Jan 2007</p><p>PMCID:PMC2040241.</p><p>© 2007 The Authors Journal compilation © 2007 Blackwell Publishing Ltd</p> Results are presented as boxes with the horizontal line inside the box representing the mean and the vertical line representing the interquartile range (10th–90th centiles). The extreme values are presented as circles. The d3/d3 + fl/d3 group (or D group) is in white and the fl/fl group is in grey

Studentized residuals in the three genotype groups are calculated according to the KIGS growth prediction model for SGA, incorporating rhGH dose, age and weight at start of therapy as well as gender-adjusted midparental height

<p><b>Copyright information:</b></p><p>Taken from "GH responsiveness in a large multinational cohort of SGA children with short stature (NESTEGG) is related to the exon 3 GHR polymorphism"</p><p></p><p>Clinical Endocrinology 2007;67(3):457-461.</p><p>Published online Jan 2007</p><p>PMCID:PMC2040241.</p><p>© 2007 The Authors Journal compilation © 2007 Blackwell Publishing Ltd</p> Results are presented as boxes with the horizontal line inside the box representing the mean and the vertical line representing the interquartile range (10th–90th centiles). Positive studentized residuals indicate growth that exceeded the prediction, negative values growth below the prediction. The asterisk indicates a significant difference between the predicted growth velocity and the observed growth velocity ( = 0·04)