Implikasi Pengaruh Kinerja dan Kepuasan Kerja Serta Komitmen Keorganisasian terhadap Iklim Organisasi Sekretariat Dprd di Sumatera Selatan

Tujuan Penelitian untuk mengkaji pengaruh kinerja, kepuasan kerja dan komitmen keorganisasian terhadap iklim organisasi pada Sekretariat DPRD di Sumatera Selatan. Persoalan iklim organisasi pada Sekretariat DPRD menarik dikaji lebih mendalam, karena berkaitan dengan hubungan antara legislasi dan eksekutif. Penelitian kuantitatif metode survey konfirmatif bersifat deskriptif dan verifikatif. Lokus pada Sekretariat DPRD Provinsi Sumatera Selatan, Kota Palembang, Kabupaten Ogan Komering Ilir, Kabupaten Ogan Ilir dan Kabupaten Banyuasin; analisis data menggunakan instrumen SEM-Listreal dilengkapi dengan SPSS; Penelitian ini dilaksanakan dalam jangka waktu 4 bulan yaitu Maret 2016 sampai dengan September 2016; populasi dan sampel jenuh sebanyak 225 responden pengumpulan data menggunakan kuesioner.Kinerja berpengaruh positif dan signifikan terhadap kepuasan kerja dengan T hitung 6,75 > 1,96 dengan koefisien 0,87, kinerja memengaruhi iklim organisasi dengan T hitung 4,87 > 1,96 dan koefisien 0,74, kinerja memengaruhi positif dan signifikan komitmen organisasi dengan T hitung 9,99 < 1,96 dan kofisien 0,53, kepuasan kerja tidak berpengaruh terhadap iklim organisasi dengan T hitung 0,88 < 1,96 dan koefisein 0,12, kepuasan kerja secara positif dan sifnifikan terhadap komitmen organisasi dengan T hitung 2,96 > 1,96 dan koefisien 0,32, komitmen organisasi tidak berpenaruh terhadap iklim organisasi dengan T hitung 0,67 > 1,96 dan koefisein 0,07 dan kinerja, komitmen organisasi dan kepuasan kerja memengaruhi iklim organisasi sebesar 57%. berdasarkan hasil persamaan structural IO = 0.07*KO + 0.12*KK + 0.74*KJ+0,43E.Dari hasil penelitian dapat disusun kerangka strategi dalam manajemen Sekretariat DPRD di Sumatera selatan bahwa “Untuk meningkatkan iklim organisasi pada Sekretariat DPRD Di Sumatera Selatan yang kondusif dengan memberikan penghargaan Dukungan Sekretariat DPRD oleh DPRD, melalui peningkatan kinerja pegawai Sekretariat DPRD yang mampu bekerja dengan prinsip saling mendukung dan melengkapi dalam pelaksanaan tugas

Sinergisme Pengaruh Pengembangan Karier dan Iklim Organisasi melalui Moderasi Motivasi Kerja terhadap Implementasi Good Governance Sekretariat Dprd dalam Wilayah Sumatera Selatan

Penelitian ini ditujukan untuk melihat faktor-faktor yang memengaruhi implikasi prinsip-prinsip good governance Sekretariat Dewan Perwakilan Rakyat Daerah dalam wilayah Sumatera Selatan. Penelitian ini menggunakan metode survey konfirmatif bersifat deskriptif verifikatif. Analisis data menggunakan statistika deskriptif dan statistika inferensial Populasi dan sampel penelitian menggunakan sampel jenuh. Metode analisis menggunakan Structural Equation Modeling (SEM). Pengujian hipotesis dilakukan dengan menggunakan program AMOS version 20.Hasil penelitian menunjukkan bahwa ; Iklim organisasi tidak memengaruhi motivasi kerja dengan signifikansi (P) 0,725 > 0,05 dan nilai CR sebesar -0,352 < 1,96, pengembangan karir memengaruhi motivasi kerja dengan signifikansi (P) *** < 0,05 dan nilai CR sebesar 3.666 > 1,96, iklim organisasi dan pengembangan karir secara bersama-sama memengaruhi motivasi kerja, dengan output squared multiple correlations 19,9%, Iklim organisasi memengaruhi good governance dengan signifikansi (P) 0,043 < 0,05 dan CR 2.023 > 1,98, pengembangan karir memengaruhi good governance dengan tingkat signifikansi (P) 0,001 < 0,05 dan nilai CR 3,266 > 1,96, motivasi kerja memengaruhi good governance dengan signifikansi 0,022 < 0,05 dan CR nilai 2,286 > 1,96, iklim organisasi, pengembangan karir dan motivasi kerja secara bersama-sama memengaruhi good governance, sesuai output squared multiple correlations determinasi 43,5 %Rekomendasi penelitian perlu melakukan penelitian untuk mengetahui pengaruh variasi variabel diluar penelitian yang memengaruhi good governance Sekretariat DPRD, Semoga !Kata kunci ; Good Governance, Pengembangan karier, iklim oraginsasi dan motivasi kerj

Developing and Validating of a Managerial Procedures Manual for Head Nurses

The managerial skills are a set of behaviors based on knowledge that can be learned through procedure. Procedures are descriptions of how to carry out an activity. Procedures manual is essential to ensure consistency and quality in products and services. The aim of this study was to develop and validate a managerial procedure manual for head nurses at Ain-shams University Hospital. The study was conducted in Ain Shams University Hospital using operational design. It included a group of 78 head nurses for assessment and a jury group consisting of 16 faculty members of Nursing Administration and 8 nursing directors and assistants. Data were collected using a head nurses' self-administered questionnaire and opinionnaire form for the jury group. The researchers discussed the idea of the study with representatives of the hospital administration to reach to an agreement regarding the importance of the proposed manual and its content, then assessed head nurses’ view of the importance of a managerial manual. The results showed that 25.6% of the head nurses did not know about the presence of a manual for managerial nursing procedures, 96.2% expressed the need for such manual, and 70.7% reported having faced problems due to lack of such manual. Based on analysis of the data the researchers developed the manual that was validated by the jury group, and distributed to head nurses after approval of the hospital administration. The hospital administration participated in all steps of the development of the manual, and adopted its use in the setting. The effectiveness of the manual in reducing head nurses' stress related to managerial problems needs to be assessed after a few months of implementation. Key words: Head nurse, Manual, Managerial skills and Managerial procedure

Spatial Distribution and Ecological Risk Assessment of Trace Metals in Surface Sediments of Lake Qarun Wetland, Egypt

Wetlands sediments could be critical indicators to control contamination in the aquatic ecosystem. Qarun Lake is regarded as the third biggest lake in Egypt that is not related to any sea. Twelve georeferenced sediment samples were gathered in September, 2020 from the different locations. Five heavy metals (Pb, Cd, Cr, Ni, and Co) were measures in the sediments estimated by Atomic Absorption Spectrophotometer. Grain size and content of organic matters in the sediment were estimated on the basis of standard assays, as well as the contamination factor, geoaccumulation index, ecological risk factor, contamination degree and potential ecological risk index in the sediment. Data revealed that the average concentration could be arranged as Ni (27.36 mg k g-1) > Pb (18.28 mg k g-1) > Cr (15.31 mg k g-1) > Co (11.16 mg k g-1) > Cd (23.31 mg k g-1). Cd, Co and Pb were estimated to be in the range of EU (2002) and the US EPA (1999), while Co and Ni in the range of EU (2002). The ecological risk index (Er) of the studied elements in sediments of lake could be arranged as: Ni > Pb > Co > Cd > Cr. In addition, the highest-integrated potential ecological risk was on the south side of the lake, which is subjected to huge amounts of drainage water composed of organic and inorganic pollutants

Combined FDG-PET/CT for the detection of unknown primary tumors: systematic review and meta-analysis

The aim of this study was to systematically review and meta-analyze published data on the diagnostic performance of combined 18F-fluoro-2-deoxyglucose positron emission tomography/computed tomography (FDG-PET/CT) in the detection of primary tumors in patients with cancer of unknown primary (CUP). A systematic search for relevant studies was performed of the PubMed/MEDLINE and Embase databases. Methodological quality of the included studies was assessed. Reported detection rates, sensitivities and specificities were meta-analyzed. Subgroup analyses were performed if results of individual studies were heterogeneous. The 11 included studies, comprising a total sample size of 433 patients with CUP, had moderate methodological quality. Overall primary tumor detection rate, pooled sensitivity and specificity of FDG-PET/CT were 37%, 84% (95% CI 78–88%) and 84% (95% CI 78–89%), respectively. Sensitivity was heterogeneous across studies (P = 0.0001), whereas specificity was homogeneous across studies (P = 0.2114). Completeness of diagnostic workup before FDG-PET/CT, location of metastases of unknown primary, administration of CT contrast agents, type of FDG-PET/CT images evaluated and way of FDG-PET/CT review did not significantly influence diagnostic performance. In conclusion, FDG-PET/CT can be a useful method for unknown primary tumor detection. Future studies are required to prove the assumed advantage of FDG-PET/CT over FDG-PET alone and to further explore causes of heterogeneity

Long-term outcome and patterns of failure in patients with advanced head and neck cancer

<p>Abstract</p> <p>Purpose</p> <p>To access the long-time outcome and patterns of failure in patients with advanced head and neck squamous cell carcinoma (HNSCC).</p> <p>Methods and materials</p> <p>Between 1992 and 2005 127 patients (median age 55 years, UICC stage III n = 6, stage IV n = 121) with primarily inoperable, advanced HNSCC were treated with definite platinum-based radiochemotherapy (median dose 66.4 Gy). Analysed end-points were overall survival (OS), disease-free survival (DFS), loco-regional progression-free survival (LPFS), development of distant metastases (DM), prognostic factors and causes of death.</p> <p>Results</p> <p>The mean follow-up time was 34 months (range, 3-156 months), the 3-, 5- and 10-year OS rates were 39%, 28% and 14%, respectively. The median OS was 23 months. Forty-seven patients achieved a complete remission and 78 patients a partial remission. The median LPFS was 17 months, the 3-, 5- and 10-year LPFS rates were 41%, 33% and 30%, respectively. The LPFS was dependent on the nodal stage (p = 0.029). The median DFS was 11 months (range, 2-156 months), the 3-, 5- and 10-year DFS rates were 30%, 24% and 22%, respectively. Prognostic factors in univariate analyses were alcohol abuse (n = 102, p = 0.015), complete remission (n = 47, p < 0.001), local recurrence (n = 71, p < 0.001), development of DM (n = 45, p < 0.001; median OS 16 months) and borderline significance in nodal stage N2 versus N3 (p = 0.06). Median OS was 26 months with lung metastases (n = 17). Nodal stage was a predictive factor for the development of DM (p = 0.025). Cause of death was most commonly tumor progression.</p> <p>Conclusions</p> <p>In stage IV HNSCC long-term survival is rare and DM is a significant predictor for mortality. If patients developed DM, lung metastases had the most favourable prognosis, so intensified palliative treatment might be justified in DM limited to the lungs.</p

HPV infection and p53 and p16 expression in esophageal cancer: are they prognostic factors?

Background: Esophageal squamous cell carcinoma (ESCC) is a highly lethal malignant tumor. Currently, Human papillomavirus (HPV) is suggested as a potential risk factor for esophageal cancer (EC) in addition to the classic risk factors, alcohol and tobacco, but this hypothesis still remains contradictory. We sought to investigate wether HPV and well-known biomarkers (p16 and p53) and patient-related factors that may have impact on survival of ESCC. Methods: We conducted a prospective cohort study. By using multiplex PCR, we determined the prevalence of high risk HPV in ESCC, and evaluated the immunohistochemical expression of p16 and p53, molecular markers related to esophageal carcinogenesis in order to verify the potential influence of these variables in patients's survival. Survival rates were estimated using Kaplan-Meier methods. A multivariate confirmatory model was performed using Cox proportional hazards regression. Results: Twelve (13.8%) of 87 patients were HPV-DNA positive. Positive reactions of p16 and p53 were 10.7% and 68.6%, respectively. Kaplan-Meier analysis indicated that men (p = 0.025) had poor specific-cancer survival and a shorter progression-free survival (p = 0.050) as compared to women; III or IV clinical stage (p < 0.019) had poor specific-cancer survival and a shorter progression-free survival (p < 0.001) compared to I and II clinical stage; not submitted to surgery (< 0.001) and not submitted to chemoradiotherapy (p = 0.039) had a poor specific-cancer survival, as well. The multivariate analysis showed that HPV, p16 and p53 status are not predictive parameters of progression-free and specific-cancer survival. Conclusion: HPV infection and p53 and p16 expression are not prognostic factors in ESCC.CNPq Universal for providing supplies to the largest study, of which this study is a part of, entitled “The role of human papillomavirus (HPV) as the etiologic agent of esophageal cancer. A cross-sectional study, case-control and longitudinal at Barretos Cancer Hospital”; (Grant number 482666/2012–9 to ALF); INCT HPV [Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP) [Grant number 08/57889–1 to LLV]; Conselho Nacional de Desenvolvimento Científico e Tencnológico (CNPq) (Grant number 573799/ 2008–3 to LLV)].info:eu-repo/semantics/publishedVersio