1,681 research outputs found
Statistical performance analysis with dynamic workload using S-NET
Volkmar Wieser, Philip K. F. Hölzenspies, Michael RoĂbory, and Raimund Kirner, 'Statistical performance analysis with dynamic workload using S-NET'. Paper presented at the Workshop on Feedback-Directed Compiler Optimization for Multi-Core Architectures. Paris, France 23-25 January 2012In this paper the ADVANCE approach for engineering con- current software systems with well-balanced hardware ef- ficiency is adressed using the stream processing language S-Net. To obtain the cost information in the concurrent system the metrics throughput, latency, and jitter are evalu- ated by analyzing generated synthetical data as well as using an industrial related application in the future. As fall-out an Eclipse plugin for S-Net has been developed to provide sup- port for syntax highlighting, content assistance, hover help, and more, for easier and faster development. The presented results of the current work are on the one hand an indicator for the status quo of the ADVANCE vision and on the other hand used to improve the applied statistical analysis tech- niques within ADVANCE. Like the ADVANCE project, this work is still under development, but further improvements and speedups are expected in the near future
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Chalcophile elements track the fate of sulfur at KÄ«lauea Volcano, Hawai'i
© 2020 Elsevier Ltd Chalcophile element concentrations in melt inclusions and matrix glasses may be used to investigate low pressure degassing processes, as well as sulfide saturation during crustal fractionation, and mantle melting. Erupted products from KÄ«lauea Volcano, HawaiÊ»i, record three stages of sulfide saturation (in the mantle, crust, and within lava lakes), separated by episodes of sulfide resorption (i.e., sulfide undersaturation) during ascent through the thick Hawaiian lithosphere, and during syn-eruptive degassing. The presence of residual sulfides in the mantle source throughout the melting interval accounts for the high S concentrations of KÄ«lauean primary melts (1387â1600 ppm). Residual sulfides retain chalcophile elements during melting, decoupling the variability of these elements in high MgO melts from that of lithophile elements. Decompression associated with magma ascent through the thick Hawaiian lithosphere drives an increase in the sulfide concentration at sulfide saturation (SCSS2â), resulting in shallow storage reservoirs (âŒ1â5 km depth) being supplied with sulfide-undersaturated melts. A drop in temperature, coupled with major element changes during the fractionation of olivine, causes the SCSS2â to decrease. Combined with an increase in melt S contents during fractionation, this initiates a second stage of sulfide saturation at relatively high MgO contents (âŒ12 wt%). Syn-eruptive degassing of S drives the resorption of sulfides in contact with the carrier liquid. The covariance structure of Cu, MgO and Ni contents in melt inclusions and matrix glasses indicates that the dissolution of sulfides effectively liberates sulfide-hosted Cu and Ni back into the melt, rather than the vapour phase. The contrasting behaviour of Cu, Ni, Se and S during sulfide resorption indicates that the chalcophile element signature of the KÄ«lauean plume is largely controlled by silicate melt-vapour partitioning, rather than sulfide-vapour partitioning. The participation of dense sulfide liquids in shallow degassing processes may result from their direct attachment to buoyant vapour bubbles, or olivine crystals which were remobilized prior to eruption. Sulfide resorption obscures the textural and chemical record of sulfide saturation in matrix glasses, but not in melt inclusions, which are isolated from this late-stage release of chalcophile elements. The partitioning of S between the dissolving sulfide, melt and the vapour phase accounts for approximately 20% of the total S release into the atmosphere
Iatrogenic nerve injury in primary and revision reverse total shoulder arthroplasty
INTRODUCTION
Iatrogenic nerve injury in orthopedic surgery can impair functional outcomes. During the last years, a steady increase in the number of performed reverse total shoulder arthroplasties has been reported and complications associated with this procedure are continuously described. Neurological complications, however, remain underreported. The aims of this study were to calculate the incidence of iatrogenic nerve injury after primary and revision reverse total shoulder arthroplasty in a large patient cohort, as well as identify associated patient-and surgery-related risk factors.
MATERIALS AND METHODS
A retrospective review of our institution's internal Reverse Total Shoulder Arthroplasty (RTSA) database from September 2005 to December 2019 was undertaken and 34 patients with iatrogenic nerve injuries were identified, resulting in a neurological complication rate of 2.6%. Group comparisons between patients with nerve injuries (nâ=â34) and the remaining cohort without nerve injuries (nâ=â1275) were performed to identify patient- and surgery-related risk factors.
RESULTS
Of the 34 cases with iatrogenic nerve injury, damage to terminal nerve branches occurred in 21 patients, whereas a brachial plexus lesion was diagnosed in the other 13. Nerve revision surgery was necessary in four patients. At final follow-up 13 patients (45%) had residual motor deficits and 17 (59%) had residual sensory deficits. Higher numbers of previous surgeries of the affected shoulder correlated with subsequent nerve injury (pâ=â0.035). Operative time was significantly longer in patients, who developed a neurologic deficit, showing a correlation between duration of surgery and occurrence of nerve injury (pâ=â0.013). Patients with neurologic complications were significantly younger than patients without nerve damage (median 68 vs. 72Â years, pâ=â0.017).
CONCLUSIONS
In specialists' hands reverse total shoulder arthroplasty is a rather safe procedure regarding the risk of neurologic injury. However, multiple previous surgeries of the affected shoulder increase the risk of neurological complications. Cases with post-operative neurologic compromise are rare and usually recover well, with few patients suffering long-term functional deficits from iatrogenic nerve injury.
LEVEL OF EVIDENCE
Level III, retrospective cohort study
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In-situ vitrification (ISV) organic-surrogate vapor emissions during a 1-ton pilot melt. Draft report
Pilot tests of a commercial soil vitrification process for entombing Animal/Chemical and Glass Hole area wastes were evaluated by incorporating perfluorocarbon tracers (PFTs) into aqueous and organic {open_quotes}wastes{close_quotes} within bottles of the type buried in typical Brookhaven-type holes. The objective was to add sufficient known PFT quantities of two or more types in the aqueous and organic phases while, at the same time, surrounding the test pit with known emission rate PFT sources, one type in the soil and another type in the air, such that monitoring of the air above ground and below ground would allow computation of the fugitive emission rates from the process as it occurred. Hood off-gas PFT concentrations were also to be monitored in order to verify the fraction present; claims have been made that greater than 99% of pit organics are destroyed during the melt. The output was to be the percentage escape (i.e., not captured by the hood) of pit aqueous and organic phases as the vitrification process proceeded. The actual melt commenced at 1350 on Monday 24 June 1996 and continued for just short of 48 hours. By the next day it was clear from the real-time PFT analyzer that above-ground fugitive emissions were not assessable because substantial PFT vapors were fumigating the area from the exhaust stack of the ISV hood`s soil vapor extraction (SVE) processing system. That sampling component was then switched to the stack to compare hood off-gas concentrations before and after the charcoal filtering
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VESIcal Part I: An Open-Source Thermodynamic Model Engine for Mixed Volatile (H<inf>2</inf>O-CO<inf>2</inf>) Solubility in Silicate Melts
Abstract: Thermodynamics has been fundamental to the interpretation of geologic data and modeling of geologic systems for decades. However, more recent advancements in computational capabilities and a marked increase in researchers' accessibility to computing tools has outpaced the functionality and extensibility of currently available modeling tools. Here, we present VESIcal (Volatile Equilibria and Saturation Identification calculator): the first comprehensive modeling tool for H 2 O, C O 2 , and mixed ( H 2 Oâ C O 2 ) solubility in silicate melts that: (a) allows users access to seven of the most popular models, plus easy interâcomparison between models; (b) provides universal functionality for all models (e.g., functions for calculating saturation pressures, degassing paths, etc.); (c) can process large datasets (1,000s of samples) automatically; (d) can output computed data into an Excel spreadsheet or CSV file for simple postâmodeling analysis; (e) integrates plotting capabilities directly within the tool; and (f) provides all of these within the framework of a python library, making the tool extensible by the user and allowing any of the model functions to be incorporated into any other code capable of calling python. The tool is presented within this manuscript, which may be read as a static PDF but is better experienced via the Jupyter Notebook version of this manuscript. Here, we present worked examples accessible to python users with a range of skill levels. The basic functions of VESIcal can also be accessed via a web app (https://vesical.anvil.app). The VESIcal python library is openâsource and available for download at https://github.com/kaylai/VESIcal, or it can be installed using pip. It is recommended to read and interact with this manuscript as an executable Jupyter Notebook, available at https://mybinder.org/v2/gh/kaylai/vesical-binder/HEAD?filepath=Manuscript.ipynb
Treatment outcomes of patients with Cutibacterium acnes-positive cultures during total joint replacement revision surgery: a minimum 2-year follow-up
INTRODUCTION
Periprosthetic joint infection (PJI) is a devastating complication following total joint replacement (TJR). Cutibacterium acnes (C. acnes) is a low virulent skin commensal, commonly found during TJR revision surgery for "aseptic" causes. The purpose of the present study was to report the treatment outcomes of patients with C. acnes contamination or infection in the presence of a TJR treated with a revision surgeryâ±âimplant exchangeâ±âprolonged (â„â8 weeks) postoperative antibiotics.
METHODS
Medical records of patients with at least one positive C. acnes culture in intraoperative tissue samples or sonication fluid from a TJR revision surgery between January 2005 and December 2014 were retrospectively evaluated. The primary endpoint was infection eradication according to Delphi criteria. The diagnostic accuracy of preoperative TJR aspiration regarding the diagnosis of C. acnes PJI was also investigated.
RESULTS
A total of 52 TJR (28 shoulders, 17 hips, 7 knees) in 52 patients (35 males, 17 females) with an average age of 63â±â11 (33-86) years were included. At an average follow-up of 67â±â33 (24-127) months, the infection eradication of C. acnes PJI was 97% regardless of the surgical treatment or administration of prolonged postoperative antibiotics. The incidence of unsuspected C. acnes PJI was 28.8%. The sensitivity and specificity of preoperative joint aspiration in detecting C. acnes PJI were 59% and 88%, whereas the PPV and NNV were 83% and 67%, respectively.
CONCLUSION
Infection eradication of C. acnes PJI was very high at a minimum follow-up of 24Â months, suggesting that C. acnes PJI could be adequately treated with a combination of revision surgery and prolonged postoperative antibiotics. The preoperative diagnosis of C. acnes PJI might be challenging with more than one-quarter of patients presenting without suspicion of C. acnes PJI. The appropriate treatment of patients with a single positive culture remains still unclear. A negative TJR aspiration should not rule out a C. acnes PJI, especially in the presence of clinical correlates of infection.
LEVEL OF EVIDENCE
Retrospective case-control study, Level III.
IRB APPROVAL
Kantonale Ethikkommission ZĂŒrich, BASEC Nr.:2017-00567
Search for the Hypothetical pi -> mu x Decay
The KARMEN collaboration has reported the possible observation of a hitherto
unknown neutral and weakly interacting particle x, which is produced in the
decay pi -> mu + x with a mass m(x) = 33.9 MeV. We have searched for this
hypothetical decay branch by studying muons from pion decay in flight with the
LEPS spectrometer at the piE3 channel at PSI and find branching ratios BR(pi-
to mu- anti-x) < 4e-7 and BR(pi+ to mu+ x) < 7e-8 (95\% C.L.). Together with
the limit BR > 2e-8 derived in a recent theoretical paper our result would
leave only a narrow region for the existence of x if it is a heavy neutrino.Comment: 10 pages, TeX (uses epsf), 3 Postscript figures uu-encode
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