Socialist Dandies International: East Europe, 1946-1959

This article maps the looks and lifestyle choices of small groups of young, like-minded people who emerged in the postwar Soviet Union and East Europe in the background of huge political, social, and cultural changes. With their androgynous bodies wrapped in drape jackets and narrow trousers, and their love of jazz and swing, these young men stood in a sharp contrast to the official ideology that promoted socialism as a new, pure, and highly rationalized project, its ideal robust and strong man, and its mass culture that insisted on educational and restrained forms of entertainment. Through the categories of dress, body, and big city, the article investigates the clashes, and the eventual truce, between the socialist streamlined and rationalized master narrative and the young dandies' fragmented and disordered narrative. The article argues that the socialist dandies were not politically minded, and that their challenge to the officially proclaimed values was informed by their adolescent recklessness and a general postwar desolation. They were declared state enemies because the socialist regimes did not allow for alternative types of modernity. Consequently, the authorities condemned the young dandies' looks and interests as cosmopolitan, because they originated in the West, and as artificial, since they belonged to the culture that had preceded a new socialist world

The HLA ligandome of oropharyngeal squamous cell carcinomas reveals shared tumour-exclusive peptides for semi-personalised vaccination

Background The immune peptidome of OPSCC has not previously been studied. Cancer-antigen specific vaccination may improve clinical outcome and efficacy of immune checkpoint inhibitors such as PD1/PD-L1 antibodies. Methods Mapping of the OPSCC HLA ligandome was performed by mass spectrometry (MS) based analysis of naturally presented HLA ligands isolated from tumour tissue samples (n = 40) using immunoaffinity purification. The cohort included 22 HPV-positive (primarily HPV-16) and 18 HPV-negative samples. A benign reference dataset comprised of the HLA ligandomes of benign haematological and tissue datasets was used to identify tumour-associated antigens. Results MS analysis led to the identification of naturally HLA-presented peptides in OPSCC tumour tissue. In total, 22,769 peptides from 9485 source proteins were detected on HLA class I. For HLA class II, 15,203 peptides from 4634 source proteins were discovered. By comparative profiling against the benign HLA ligandomic datasets, 29 OPSCC-associated HLA class I ligands covering 11 different HLA allotypes and nine HLA class II ligands were selected to create a peptide warehouse. Conclusion Tumour-associated peptides are HLA-presented on the cell surfaces of OPSCCs. The established warehouse of OPSCC-associated peptides can be used for downstream immunogenicity testing and peptide-based immunotherapy in (semi)personalised strategies

Programma, De Rhetorica Mosis : Quo ad Illustrissimi & Celsissimi Comitis ac Domini, Dn. Ludovici Friderici, S. R. I. Qvatuor-Viri, Comitis Schwartzburgi & Hohnsteini ... & Illustrissimæ & Celsissimæ Comitis & Dominæ Dn. Sophiæ Julianæ, Comitis Schwartzburgi & Hohnsteini ... bono omine Conjunctas Natales Festivitates devotissimè celebrandas, Magnificos Dn. Scholarchas & quosvis Scholarum Fautores unà cum honoratissimo Domino Rectore invitare voluit

PROGRAMMA, DE RHETORICA MOSIS : QUO AD ILLUSTRISSIMI & CELSISSIMI COMITIS AC DOMINI, DN. LUDOVICI FRIDERICI, S. R. I. QVATUOR-VIRI, COMITIS SCHWARTZBURGI & HOHNSTEINI ... & ILLUSTRISSIMÆ & CELSISSIMÆ COMITIS & DOMINÆ DN. SOPHIÆ JULIANÆ, COMITIS SCHWARTZBURGI & HOHNSTEINI ... BONO OMINE CONJUNCTAS NATALES FESTIVITATES DEVOTISSIMÈ CELEBRANDAS, MAGNIFICOS DN. SCHOLARCHAS & QUOSVIS SCHOLARUM FAUTORES UNÀ CUM HONORATISSIMO DOMINO RECTORE INVITARE VOLUIT Programma, De Rhetorica Mosis : Quo ad Illustrissimi & Celsissimi Comitis ac Domini, Dn. Ludovici Friderici, S. R. I. Qvatuor-Viri, Comitis Schwartzburgi & Hohnsteini ... & Illustrissimæ & Celsissimæ Comitis & Dominæ Dn. Sophiæ Julianæ, Comitis Schwartzburgi & Hohnsteini ... bono omine Conjunctas Natales Festivitates devotissimè celebrandas, Magnificos Dn. Scholarchas & quosvis Scholarum Fautores unà cum honoratissimo Domino Rectore invitare voluit (1) Titelseite (1) Text (2

Programma De Problemate : Quo ad Illustrissimi & Celsissimi Comitis ac Domini, Dn. Friedrici Anthonii, S. R. I. Qvatuor-Viri, Comitis Schwartzburgi & Hohnsteini ... Festum Natalitium à Deo propitio multis lætitiarum causis amplificatum, & à nobis religiosè celebrandum, Magnificos Scholæ provincialis Ephoros, & laudatissimos Bonarum Artium Cultores, unà cum peramanter colendo Dn. Rectore, decenter invitare voluit

PROGRAMMA DE PROBLEMATE : QUO AD ILLUSTRISSIMI & CELSISSIMI COMITIS AC DOMINI, DN. FRIEDRICI ANTHONII, S. R. I. QVATUOR-VIRI, COMITIS SCHWARTZBURGI & HOHNSTEINI ... FESTUM NATALITIUM À DEO PROPITIO MULTIS LÆTITIARUM CAUSIS AMPLIFICATUM, & À NOBIS RELIGIOSÈ CELEBRANDUM, MAGNIFICOS SCHOLÆ PROVINCIALIS EPHOROS, & LAUDATISSIMOS BONARUM ARTIUM CULTORES, UNÀ CUM PERAMANTER COLENDO DN. RECTORE, DECENTER INVITARE VOLUIT Programma De Problemate : Quo ad Illustrissimi & Celsissimi Comitis ac Domini, Dn. Friedrici Anthonii, S. R. I. Qvatuor-Viri, Comitis Schwartzburgi & Hohnsteini ... Festum Natalitium à Deo propitio multis lætitiarum causis amplificatum, & à nobis religiosè celebrandum, Magnificos Scholæ provincialis Ephoros, & laudatissimos Bonarum Artium Cultores, unà cum peramanter colendo Dn. Rectore, decenter invitare voluit ([1]) Title page ([1]) Text ([2]