Association between individual SNP and milk yield from a genome-wide association study.

<p>Each dot represents a SNP that has passed the quality threshold and the high above the X axis is proportional to the strength of the association.</p

Q-Q plot.

<p>Quantile-Quantile plot showing P-values from GWAS. Deviations from the distribution under the hypothesis (null hypothesis of no association) are showed.</p

Numbers of heterozygous SNP per chromosome.

<p>SNPs are annotated per bovine chromosome as the buffalo genome is not yet assigned to chromosomes.</p

Significant SNPs obtained in the GWA study for milk yield in 529 Italian Mediterranean buffalo.

<p>Significant SNPs obtained in the GWA study for milk yield in 529 Italian Mediterranean buffalo.</p

SNP GAP.

<p>The distribution of the gaps between the 90,000 SNPs with respect to their location in the bovine UMD 3.1 sequence.</p

SNP MAF.

<p>Distribution of SNP Minor Allele Frequency (MAF) for Mediterranean, Murrah, Jaffarabadi and Nili-Ravi breeds used in the design of the SNP panel.</p

IPA merged network.

<p>The focus molecules are indicated in bold. One of the link molecules in the merging networks is D-Glucose, important for the milk synthesis and involved in the gluconeogenesis pathway.</p

MDS.

<p>Multidimensional scaling plot showing the relationship among individuals from the four farms used in this study.</p

IPA molecule function network.

<p>The focus molecules are highlighted in purple. This network shows the central role of D-Glucose molecule and its connections with the function of the molecules close to significant SNPs in the present study.</p

Criteria of SNP used in each wave of SNP selection, total number that met the criteria, and number used from that wave.

<p>Criteria of SNP used in each wave of SNP selection, total number that met the criteria, and number used from that wave.</p