2,754 research outputs found
Wavefront sensing of atmospheric phase distortions at the Palomar 200-in. telescope and implications for adaptive optics
Major efforts in astronomical instrumentation are now being made to apply the techniques of adaptive optics to the correction of phase distortions induced by the turbulent atmosphere and by quasi-static aberrations in telescopes themselves. Despite decades of study, the problem of atmospheric turbulence is still only partially understood. We have obtained video-rate (30 Hz) imaging of stellar clusters and of single-star phase distortions over the pupil of the 200" Hale telescope on Palomar Mountain. These data show complex temporal and spatial behavior, with multiple components arising at a number of scale heights in the atmosphere; we hope to quantify this behavior to ensure the feasibility of adaptive optics at the Observatory. We have implemented different wavefront sensing techniques to measure aperture phase in wavefronts from single stars, including the classical Foucault test, which measures the local gradient of phase, and the recently-devised curvature sensing technique, which measures the second derivative of pupil phase and has formed the real-time wavefront sensor for some very productive astronomical adaptive optics. Our data, though not fast enough to capture all details of atmospheric phase fluctuations, provide important information regarding the capabilities that must be met by the adaptive optics system now being built for the 200" telescope by a team at the Jet Propulsion Lab. We describe our data acquisition techniques, initial results from efforts to characterize the properties of the turbulent atmosphere at Palomar Mountain, and future plans to extract additional quantitative parameters of use for adaptive optics performance predictions
SHARP: A Spatially Higher-order, Relativistic Particle-in-Cell Code
Numerical heating in particle-in-cell (PIC) codes currently precludes the
accurate simulation of cold, relativistic plasma over long periods, severely
limiting their applications in astrophysical environments. We present a
spatially higher-order accurate relativistic PIC algorithm in one spatial
dimension, which conserves charge and momentum exactly. We utilize the
smoothness implied by the usage of higher-order interpolation functions to
achieve a spatially higher-order accurate algorithm (up to fifth order). We
validate our algorithm against several test problems -- thermal stability of
stationary plasma, stability of linear plasma waves, and two-stream instability
in the relativistic and non-relativistic regimes. Comparing our simulations to
exact solutions of the dispersion relations, we demonstrate that SHARP can
quantitatively reproduce important kinetic features of the linear regime. Our
simulations have a superior ability to control energy non-conservation and
avoid numerical heating in comparison to common second-order schemes. We
provide a natural definition for convergence of a general PIC algorithm: the
complement of physical modes captured by the simulation, i.e., those that lie
above the Poisson noise, must grow commensurately with the resolution. This
implies that it is necessary to simultaneously increase the number of particles
per cell and decrease the cell size. We demonstrate that traditional ways for
testing for convergence fail, leading to plateauing of the energy error. This
new PIC code enables us to faithfully study the long-term evolution of plasma
problems that require absolute control of the energy and momentum conservation.Comment: 26 pages, 19 figures, discussion about performance is added,
published in Ap
Growth of beam-plasma instabilities in the presence of background inhomogeneity
We explore how inhomogeneity in the background plasma number density alters
the growth of electrostatic unstable wavemodes of beam plasma systems. This is
particularly interesting for blazar-driven beam-plasma instabilities, which may
be suppressed by inhomogeneities in the intergalactic medium as was recently
claimed in the literature. Using high resolution Particle-In-Cell simulations
with the SHARP code, we show that the growth of the instability is local, i.e.,
regions with almost homogeneous background density will support the growth of
the Langmuir waves, even when they are separated by strongly inhomogeneous
regions, resulting in an overall slower growth of the instability. We also show
that if the background density is continuously varying, the growth rate of the
instability is lower; though in all cases, the system remains within the linear
regime longer and the instability is not extinguished. In all cases, the beam
loses approximately the same fraction of its initial kinetic energy in
comparison to the uniform case at non-linear saturation. Thus, inhomogeneities
in the intergalactic medium are unlikely to suppress the growth of
blazar-driven beam-plasma instabilities.Comment: 10 pages, 6 figures, Accepted by ApJ, comments welcom
Importance of resolving the spectral support of beam-plasma instabilities in simulations
Many astrophysical plasmas are prone to beam-plasma instabilities. For
relativistic and dilute beams, the {\it spectral} support of the beam-plasma
instabilities is narrow, i.e., the linearly unstable modes that grow with rates
comparable to the maximum growth rate occupy a narrow range of wave numbers.
This places stringent requirements on the box-sizes when simulating the
evolution of the instabilities. We identify the implied lower limits on the box
size imposed by the longitudinal beam plasma instability, i.e., typically the
most stringent condition required to correctly capture the linear evolution of
the instabilities in multidimensional simulations. We find that sizes many
orders of magnitude larger than the resonant wavelength are typically required.
Using one-dimensional particle-in-cell simulations, we show that the failure to
sufficiently resolve the spectral support of the longitudinal instability
yields slower growth and lower levels of saturation, potentially leading to
erroneous physical conclusion.Comment: 7 pages, 9 figures, accepted by Ap
Mitofusins Mfn1 and Mfn2 coordinately regulate mitochondrial fusion and are essential for embryonic development
Mitochondrial morphology is determined by a dynamic equilibrium between organelle fusion and fission, but the significance of these processes in vertebrates is unknown. The mitofusins, Mfn1 and Mfn2, have been shown to affect mitochondrial morphology when overexpressed. We find that mice deficient in either Mfn1 or Mfn2 die in midgestation. However, whereas Mfn2 mutant embryos have a specific and severe disruption of the placental trophoblast giant cell layer, Mfn1-deficient giant cells are normal. Embryonic fibroblasts lacking Mfn1 or Mfn2 display distinct types of fragmented mitochondria, a phenotype we determine to be due to a severe reduction in mitochondrial fusion. Moreover, we find that Mfn1 and Mfn2 form homotypic and heterotypic complexes and show, by rescue of mutant cells, that the homotypic complexes are functional for fusion. We conclude that Mfn1 and Mfn2 have both redundant and distinct functions and act in three separate molecular complexes to promote mitochondrial fusion. Strikingly, a subset of mitochondria in mutant cells lose membrane potential. Therefore, mitochondrial fusion is essential for embryonic development, and by enabling cooperation between mitochondria, has protective effects on the mitochondrial population
Combined Electron Magnetic Resonance and Density Functional Theory Study of Thermally Induced Free Radical Reactions in Fructose and Trehalose Single Crystals
Both as models for studying the effects of radiation on the DNA sugar unit and for applications in dosimetry, radiation-induced defects in sugars have in the past few decades been intensively studied with electron magnetic resonance (EMR) techniques, often with considerable success. However, irradiation generally gives rise to a large variety of free radicals, resulting in strongly composite Electron Paramagnetic Resonance (EPR) spectra. This complexity makes studying them quite a challenge. Despite considerable efforts, little is still known about the identity of the radicals and even less about the radical formation and transformation processes and mechanisms. At room temperature (RT) the primary radiation products, which may be stabilized upon low temperature (LT) irradiation, transform into stable radicals via multistep reaction mechanisms. While the species formed at LT are expected to be formed by simple processes, the molecular structure and geometry of the stable radicals may differ considerably from that of the intact molecule even in the solid state (crystals). Studying the intermediate radicals in the reactions occurring after LT irradiation helps elucidating the formation and identity of the stable radicals. The structural identification of these radicals is in most cases the result of a combination of EPR, Electron Nuclear Double Resonance (ENDOR) and ENDOR Induced EPR (EIE) experiments and advanced quantum chemistry calculations based on Density Functional Theory (DFT). In the present study a summary is given of the experimental EMR results obtained so far on radiation-induced radicals at different temperatures in fructose and trehalose single crystals and powders. “In situ” X-irradiation at LT (10 K) without annealing, leads to spectra strongly different from those observed after RT irradiation and offers the possibility to study and characterize the primary radiation products [1]. Performing EMR measurements on samples irradiated and/or annealed at various temperatures between LT (10 K or 77 K) and RT allows us to study the intermediate products, and such studies therefore have the potential to devise mechanistic links between the primary radicals and the stable radicals. In the present work, our own measurements are compared with results reported in the EMR literature. An outline at future experimental (EMR) and theoretical (DFT) research will also be given
Regional requirements for Dishevelled signaling during Xenopus gastrulation: separable effects on blastopore closure, mesendoderm internalization and archenteron formation
During amphibian gastrulation, the embryo is transformed by the combined actions of several different tissues. Paradoxically, many of these morphogenetic processes can occur autonomously in tissue explants, yet the tissues in intact embryos must interact and be coordinated with one another in order to accomplish the major goals of gastrulation: closure of the blastopore to bring the endoderm and mesoderm fully inside the ectoderm, and generation of the archenteron. Here, we present high-resolution 3D digital datasets of frog gastrulae, and morphometrics that allow simultaneous assessment of the progress of convergent extension, blastopore closure and archenteron formation in a single embryo. To examine how the diverse morphogenetic engines work together to accomplish gastrulation, we combined these tools with time-lapse analysis of gastrulation, and examined both wild-type embryos and embryos in which gastrulation was disrupted by the manipulation of Dishevelled (Xdsh) signaling. Remarkably, although inhibition of Xdsh signaling disrupted both convergent extension and blastopore closure, mesendoderm internalization proceeded very effectively in these embryos. In addition, much of archenteron elongation was found to be independent of Xdsh signaling, especially during the second half of gastrulation. Finally, even in normal embryos, we found a surprising degree of dissociability between the various morphogenetic processes that occur during gastrulation. Together, these data highlight the central role of PCP signaling in governing distinct events of Xenopus gastrulation, and suggest that the loose relationship between morphogenetic processes may have facilitated the evolution of the wide variety of gastrulation mechanisms seen in different amphibian species
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