Results of MRI and SPECT examination of a control subject.

<p>Magnetic Resonance Imaging and Single Photon Emission Computed Tomography demonstrating the normal scans of a control, age-matched patient with no signs of any neurodegenerative disorder.</p

Results of MRI and SPECT examinations of the proband.

<p>Magnetic Resonance Imaging revealed marked cortical and subcortical atrophy within both occipital and parietal lobes bilaterally. The atrophy was less pronounced in the frontal and temporal lobes, and the hippocampal structures of the temporal lobes were mostly preserved. Single Photon Emission Computed Tomography demonstrated severe hypoperfusion within the parietal, occipital and temporal lobes bilaterally.</p

Analysis of visuospatial dysfunction of the patient.

<p>Patient's drawings in the context of drawings by a patient with semantic dementia. (SD) scoring 19 in MMSE were presented. A) flowers drawn by the patients from memory: A1) PCA patient, A2) SD patient; B) model, C) patients' copy: C1) PCA patient, C2) SD patient. Copying pictures and drawing to command indicated severe optic ataxia and partial simultanognosia. The test was performed at first neuropsychological assessment. During the second assessment (six months later) the patient was unable to draw even simple patterns and presented with complete simultanognosia.</p