Seborrheic keratoses: a distinctive diagnoses of pigmented vulvar lesions: a case report

Seborrheic keratoses, a benign growth lesion, is a very common cutaneous lesion encountered in white races in the fourth and fifth decade. The occurrence of this lesion on the vulva is rare, as an isolated lesion or in association with lesions elsewhere. A 34-year-old woman reported with a hyperpigmented palpable lesion, approximately 5-10 mm in diameter, was found on the patient's left labium majus. The clinical differential diagnosis of the pigmented lesions of the vulva is difficult often need a biopsy

A rare clinical manifestation of spinulate demodicosis

Demodicosis is a chronic skin disease caused by Demodex mites such as Demodex folliculorum and Demodex brevis. Demodex mites live in pilosebaceous units and they are regarded as a part of the normal skin flora. Nevertheless, it has been suggested that the presence of five or more mites per cm² by the standardized skin surface biopsy technique could be considered as pathogeni

25-hydroxyvitamin D status in patients with alopecia areata

Introduction : Alopecia areata (AA) is a T cell-mediated autoimmune disease that causes inflammation around anagen-phase hair follicles. Insufficient levels of vitamin D have been implicated in a variety of autoimmune diseases. Aim : To investigate the status of serum 25-hydroxyvitamin D (25(OH)D) in patients with AA, serum 25(OH)D concentrations were compared between AA patients and healthy controls and thus determine if a possible association exists between serum 25(OH)D levels and AA. Material and methods : The study comprising 41 patients diagnosed with AA and 32 healthy controls was conducted between October 2010 and March 2011. The serum vitamin D levels of the study group were determined by high performance liquid chromatography. Serum levels of calcium, phosphorus, alkaline phosphatase, and parathyroid hormone were also evaluated. Results : The study was based on 41 patients aged between 20 and 50 (mean: 32.8 ±7.5). The control group included 32 healthy persons aged between 20 and 51 (mean: 32.7 ±7.5). Serum 25(OH)D levels in patients with AA ranged from 5.0 to 38.6 ng/ml with a mean of 8.1 ng/ml. Serum 25(OH)D levels in healthy controls ranged from 3.6 to 38.5 ng/ml with a mean of 9.8 ng/ml. There was no statistically significant difference in the serum vitamin D level between AA patients and healthy controls (p > 0.05). Conclusions : Deficient serum 25(OH)D levels are present in patients with AA. However, considering the high prevalence of vitamin D deficiency in Turkey, no difference was noted between AA patients and controls

A rare clinical manifestation of spinulate demodicosis

Demodicosis is a chronic skin disease caused by Demodex mites such as Demodex folliculorum and Demodex brevis. Demodex mites live in pilosebaceous units and they are regarded as a part of the normal skin flora. Nevertheless, it has been suggested that the presence of five or more mites per cm² by the standardized skin surface biopsy technique could be considered as pathogeni