The digital economy and actual problems of the improvement of the training system in the field of information security

Trends in the development of the global information society indicate an increasing need for professionals with well established information culture, including those with knowledge and skills to ensure information security. The development and improvement of the system of appropriate training is stated in the Doctrine of information security of the Russian Federation as one of the priority measures for the implementation of the state policy in the field of digital economy. Training in this case should include both professional and mass training. In turn, the professional training can be basic and additional. The main goal of mass education is to form a culture of information security in society, which insufficient level of was noted in the Doctrine of information security as one of the main information threats. Therefore, the paper deals with the whole spectrum of the current problems of both professional and mass training. The importance of implementing the paradigm of continuous education ("lifelong learning") is emphasized. Thus, the main purpose of this paper is to reveal the most important problems of ensuring the continuous process of formation of modern culture of information security using the capabilities of all components of the educational system

(1R,3R,3aS,8aR)-4-Oxo-3-phenyl-1-[(1R)-1-phenylethyl]decahydrocyclohepta[b]pyrrol-1-ium bromide

The title chiral compound, C23H28NO+·Br−, was obtained from an optically active aminoethanol precursor. The pyrrolidine heterocycle has an envelope conformation, with the C atom α-positioned with respect to the keto group deviating by 0.570 (6) Å from the mean plane of other atoms. The trans-fused seven-membered ring adopts a pseudo-chair conformation. The two phenyl rings form a dihedral angle of 85.1 (2)°. The cationic center and the bromide anion are connected through an N—H...Br hydrogen bond

Highly Stereoselective and Scalable Synthesis of <i>trans</i>-Fused Octahydrocyclohepta[<i>b</i>]pyrrol-4(1<i>H</i>)‑ones via the Aza-Cope–Mannich Rearrangement in Racemic and Enantiopure Forms

We have developed an efficient and stereoselective route to <i>trans</i>-fused octahydrocyclohepta­[<i>b</i>]­pyrrol-4­(1<i>H</i>)-ones. The key features of our synthesis include the regioselective epoxide ring-opening of alkynyl oxiranes and a stereoselective aza-Cope–Mannich reaction. The target compounds were prepared in 3–6 steps from commercially available starting materials (61–75% overall yield) with minimal chromatographic purification. We have devised an stereoselective route to target compounds using Shi epoxidation or (<i>R</i>)-1-phenylethylamine as a source of chirality

Highly Stereoselective and Scalable Synthesis of <i>trans</i>-Fused Octahydrocyclohepta[<i>b</i>]pyrrol-4(1<i>H</i>)‑ones via the Aza-Cope–Mannich Rearrangement in Racemic and Enantiopure Forms

We have developed an efficient and stereoselective route to <i>trans</i>-fused octahydrocyclohepta­[<i>b</i>]­pyrrol-4­(1<i>H</i>)-ones. The key features of our synthesis include the regioselective epoxide ring-opening of alkynyl oxiranes and a stereoselective aza-Cope–Mannich reaction. The target compounds were prepared in 3–6 steps from commercially available starting materials (61–75% overall yield) with minimal chromatographic purification. We have devised an stereoselective route to target compounds using Shi epoxidation or (<i>R</i>)-1-phenylethylamine as a source of chirality

Highly Stereoselective and Scalable Synthesis of <i>trans</i>-Fused Octahydrocyclohepta[<i>b</i>]pyrrol-4(1<i>H</i>)‑ones via the Aza-Cope–Mannich Rearrangement in Racemic and Enantiopure Forms

We have developed an efficient and stereoselective route to <i>trans</i>-fused octahydrocyclohepta­[<i>b</i>]­pyrrol-4­(1<i>H</i>)-ones. The key features of our synthesis include the regioselective epoxide ring-opening of alkynyl oxiranes and a stereoselective aza-Cope–Mannich reaction. The target compounds were prepared in 3–6 steps from commercially available starting materials (61–75% overall yield) with minimal chromatographic purification. We have devised an stereoselective route to target compounds using Shi epoxidation or (<i>R</i>)-1-phenylethylamine as a source of chirality

Highly Stereoselective and Scalable Synthesis of <i>trans</i>-Fused Octahydrocyclohepta[<i>b</i>]pyrrol-4(1<i>H</i>)‑ones via the Aza-Cope–Mannich Rearrangement in Racemic and Enantiopure Forms

We have developed an efficient and stereoselective route to <i>trans</i>-fused octahydrocyclohepta­[<i>b</i>]­pyrrol-4­(1<i>H</i>)-ones. The key features of our synthesis include the regioselective epoxide ring-opening of alkynyl oxiranes and a stereoselective aza-Cope–Mannich reaction. The target compounds were prepared in 3–6 steps from commercially available starting materials (61–75% overall yield) with minimal chromatographic purification. We have devised an stereoselective route to target compounds using Shi epoxidation or (<i>R</i>)-1-phenylethylamine as a source of chirality