Temperature dependence of the absorption edge of synthetic diamond

Using optical spectroscopy in the spectral range from 200 to 300 nm, the absorption edge and transmission spectra of 7 samples of synthetic diamond of IIa type in the temperature range from 12 K to 470 K was studied. Using numerical methods, the temperature dependences of optical absorption into the free exciton state were obtained for negative and positive phonon branches

Photoluminescence and optical absorption of diamond samples containing NV centers

NV center is an impurity defective complex in diamond, obtained by irradiating with highenergy electrons samples containing nitrogen in a substituting position and post radiating annealing. NV centers are observed in several charge states negative (zero phonon line at 638 nm), neutral (ZPL at 575 nm), and, possibly, positive (ZPL at 533 nm). NV centers in diamond are candidates for qubits for quantum computing, the basis of high speed magnetometric sensors, sources of single photons, and also emitting centers of optically active laser media

Carbon electronics and photonics

Diamond surpasses all known semiconductors in basic parameters, second only to gallium arsenide and graphene (a quasimetallic form of carbon) in electron mobility. For a long time, the widespread use of diamond in electronics was limited by the high cost and poor quality of both natural and synthetic raw materials. Currently, the technology of synthesis and doping of diamond has reached the necessary level for the breakthrough of diamond into electronics and photonics [1, 2]. In the first place, diamond based electronic devices will ensure long term and efficient operation in high temperature conditions and high levels of ionizing radiation, in the subterahertz frequency rang

Garcinoxanthones from Garcinia mangostana L. against SARS-CoV-2 infection and cytokine storm pathway inhibition: A viroinformatics study

Context: Mangosteen (Garcinia mangostana L.) is used in traditional medicine as an antibacterial, antioxidant, and anti-inflammatory. Aims: To determine the molecular mechanism and potential of garciniaxanthone derivate compounds from G. mangostana as SARS-CoV-2 antiviral and prevent cytokine storm through in silico approach. Methods: Ligand and protein samples were obtained from databases such as PubChem and Protein Databank, then drug-likeness analysis using Lipinski, Ghose, Veber, Egan, and Muege rules on SwissADME server, prediction of antiviral probability through PASSOnline server. Furthermore, molecular docking simulation with PyRx v1.0 software (Scripps Research, USA) with an academic license, identification of interactions and chemical bond positions of ligands on the target by PoseView server, 3D visualization of PyMOLv.2.5.2 software (Schrödinger, Inc., USA) with an academic license, molecular dynamics simulation for molecular stability prediction by CABS-flex v2.0 server, target prediction of antiviral candidate compounds by SwissTargetPrediction server, pathway analysis through STRING v11.5 database, and toxicity by ProTox-II server were used. Results: Garciniaxanthone C from G. mangostana was found to be a drug-like molecule with low toxicity. This can be a candidate for SARS-Cov-2 antiviral through inhibitor activity on two viral enzymes consisting of Mpro and replicase with a binding affinity value that is more negative than other garciniaxanthone derivates and is stable. Garciniaxanthone C is predicted to bind and inhibit pro-inflammatory proteins that trigger cytokine storms, such as NFKB1 and PTGS2. Conclusions: Garciniaxanthone derivative compounds from G. mangostana may be candidates for SARS-CoV-2 antiviral and preventing cytokine storm through garciniaxanthone C activity