7,289 research outputs found
Effect of Sodium Ions on the Electrochemical Reduction of Diethyl Fumarate in Dimethylsulfoxide and Acetonitrile
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Evolutionary Signatures In The Formation Of Low-Mass Protostars. II. Toward Reconciling Models And Observations
A long-standing problem in low-mass star formation is the "luminosity problem," whereby protostars are underluminous compared to the accretion luminosity expected both from theoretical collapse calculations and arguments based on the minimum accretion rate necessary to form a star within the embedded phase duration. Motivated by this luminosity problem, we present a set of evolutionary models describing the collapse of low-mass, dense cores into protostars. We use as our starting point the evolutionary model following the inside-out collapse of a singular isothermal sphere as presented by Young & Evans. We calculate the radiative transfer of the collapsing core throughout the full duration of the collapse in two dimensions. From the resulting spectral energy distributions, we calculate standard observational signatures (L(bol), T(bol), L(bol)/L(smm)) to directly compare to observations. We incorporate several modifications and additions to the original Young & Evans model in an effort to better match observations with model predictions; we include (1) the opacity from scattering in the radiative transfer, (2) a circumstellar disk directly in the two-dimensional radiative transfer, (3) a two-dimensional envelope structure, taking into account the effects of rotation, (4) mass-loss and the opening of outflow cavities, and (5) a simple treatment of episodic mass accretion. We find that scattering, two-dimensional geometry, mass-loss, and outflow cavities all affect the model predictions, as expected, but none resolve the luminosity problem. On the other hand, we find that a cycle of episodic mass accretion similar to that predicted by recent theoretical work can resolve this problem and bring the model predictions into better agreement with observations. Standard assumptions about the interplay between mass accretion and mass loss in our model give star formation efficiencies consistent with recent observations that compare the core mass function and stellar initial mass function. Finally, the combination of outflow cavities and episodic mass accretion reduces the connection between observational class and physical stage to the point where neither of the two commonly used observational signatures (T(bol) and L(bol)/L(smm)) can be considered reliable indicators of physical stage.NASA 1224608, 1288664, 1288658, RSA 1377304, NNX 07-AJ72GNSF AST0607793UT Austin University Continuing FellowshipAstronom
Selecting an Appropriate Damages Expert in a Patent Case; An Examination of the Current Status of Daubert
The determination of damages is a critical part of any patent case. As a plaintiff, maximizing awarded damages, whether financial or injunctive, is the ultimate objective of the patent case. As a defendant, minimizing or preventing any awarded damages is the ultimate objective.
Multimillion dollar verdicts in patent cases are now the norm and hundred plus million dollar verdicts are becoming more frequent. A lawyer who fails to devote sufficient time to this critical component of a case does the client a disservice.
There are generally two types of damages in patent cases: lost profits and a reasonable royalty. A patent owner may seek either lost profits or a reasonable royalty, or a combination of both, as long the recoveries do not overlap. The determination of patent damages awarded is a question of fact, and numerous damage theories exist within the broad categories of both lost profits and a reasonable royalty to help answer that question
Assessing Energy Storage Requirements Based on Accepted Risks
This paper presents a framework for deriving the storage capacity that an
electricity system requires in order to satisfy a chosen risk appetite. The
framework takes as inputs user-defined event categories, parameterised by peak
power-not-served, acceptable number of events per year and permitted
probability of exceeding these constraints, and returns as an output the total
capacity of storage that is needed. For increased model accuracy, our
methodology incorporates multiple nodes with limited transfer capacities, and
we provide a foresight-free dispatch policy for application to this setting.
Finally, we demonstrate the chance-constrained capacity determination via
application to a model of the British network
Enzymatic processing of replication and recombination intermediates by the vaccinia virus DNA polymerase
Poxvirus DNA polymerases play a critical role in promoting virus recombination. To test if vaccinia polymerase (E9L) could mediate this effect by catalyzing the post-synaptic processing of recombinant joint molecules, we prepared substrates bearing a nick, a 3′-unpaired overhang, a 5′ overhang, or both 3′ and 5′ overhangs. The sequence of the 5′ overhang was also modified to permit or preclude branch migration across the joint site. These substrates were incubated with E9L, and the fate of the primer strand characterized under steady-state reaction conditions. E9L rapidly excises a mispaired 3′ strand from a DNA duplex, producing a meta-stable nicked molecule that is a substrate for ligase. The reaction was not greatly affected by adding an unpaired 5′ strand, but since such molecules cannot be processed into nicked intermediates, the 3′-ended strand continued to be subjected to exonucleolytic attack. Incorporating homology into the 5′ overhang prevented this and permitted some strand assimilation, but such substrates also promoted strand-displacement DNA synthesis of a type predicted by the 1981 Moyer and Graves model for poxvirus replication. Single-strand annealing reactions are used by poxviruses to produce recombinant viruses and these data show that virus DNA polymerases can process DNA in such a manner as to both generate single-stranded substrates for such reactions and to facilitate the final processing of the reaction products
The biomechanical role of the chondrocranium and sutures in a lizard cranium
The role of soft tissues in skull biomechanics remains poorly understood. Not least, the chondrocranium, the portion of the braincase which persists as cartilage with varying degrees of mineralization. It also remains commonplace to overlook the biomechanical role of sutures despite evidence that they alter strain distribution. Here, we examine the role of both the sutures and the chondrocranium in the South American tegu lizard Salvator merianae. We use multi-body dynamics analysis (MDA) to provide realistic loading conditions for anterior and posterior unilateral biting and a detailed finite element model to examine strain magnitude and distribution. We find that strains within the chondrocraniumare greatest during anterior biting and are primarily tensile; also that strain within the cranium is not greatly reduced by the presence of the chondrocraniumunless it is given the same material properties as bone. This result contradicts previous suggestions that the anterior portion (the nasal septum) acts as a supporting structure. Inclusion of sutures to the cranium model not only increases overall strain magnitudes but also leads to a more complex distribution of tension and compression rather than that of a beam under sagittal bending
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