5 research outputs found
Analysis of lung tissues through qRT-PCR showed S-groups yielded a significantly higher expression of all TLRs in S-groups compared to their time-adjusted C-groups (p<0.05).
<p>The most significant variances were observed between S72-C72 followed by S48-C48 groups concerning TLR 2 and TLR 4, whereas the least important differences were noticed between S24-C24 regarding TLR 7 and TLR 3.</p
Expression of Toll-like receptors (TLRs) in the lungs of an experimental sepsis mouse model - Fig 2
<p><b>a-d)</b> Analysis of lung tissues through IF showed a significantly increased area (%) of expression of TLRs 2, 3, 4 and 7 in all S-groups compared to the time-adjusted C-groups (p<0.05), <b>e)</b> Among septic mice, expression of TLRs 2, 3 and 4 was higher in S48 versus S24 groups (p<0.05), S72 versus S24 groups (p<0.05) and S72 versus S48 groups whereas expression of TLR 7 was higher in S48 versus S24 groups (p<0.05), S72 versus S24 groups (p<0.05), but yet comparable between S72 and S48 groups (p>0.05).</p
Among S-groups, qRT-PCR of intestinal tissues showed significant differences between S48-S24 regarding TLR 2, 4 and 7 (p<0.05) as well as between S72-S48 and S72-S24 for all TLRs examined (p<0.05).
<p>Among S-groups, qRT-PCR of intestinal tissues showed significant differences between S48-S24 regarding TLR 2, 4 and 7 (p<0.05) as well as between S72-S48 and S72-S24 for all TLRs examined (p<0.05).</p