Convenient asymmetric synthesis of both enantiomers of 3,4-disubstituted 3,4-dihydro-1,4-benzoxazin-2-ones

<p>Both enantiomers of <i>N</i>-substituted 3-arylated 3,4-dihydro-1,4-benzoxazin-2-ones were conveniently synthesized up to 93:7 er based on the dynamic kinetic resolution of either (<i>R</i>)-pantolactone- or l-mandelate-derived α-bromo arylacetates in nucleophilic substitution with <i>N</i>-alkylated 2-aminophenols.</p