Peroxynitrite-Scavenging Glycosides from the Stem Bark of <i>Catalpa ovata</i>

Ten new glycosides, 6,10-<i>O</i>-di-<i>trans</i>-feruloyl catalpol (<b>1</b>), 6,6′-<i>O</i>-di-<i>trans</i>-feruloyl catalpol (<b>2</b>), 3,4-dihydro-6-<i>O</i>-di-<i>trans</i>-feruloyl catalpol (<b>10</b>), (8<i>R</i>,7′<i>S</i>,8′<i>R</i>)-lariciresinol 9′-<i>O</i>-β-d-(6-<i>O</i>-<i>trans</i>-feruloyl)­glucopyranoside (<b>17</b>), and ovatosides A–F (<b>18</b>–<b>22</b>, <b>24</b>), were isolated from the stem bark of <i>Catalpa ovata</i> along with 19 known compounds. All isolates, except <b>6</b> (catalposide) and <b>9</b> (6-<i>O</i>-veratroyl catalpol), were found to scavenge peroxynitrite (ONOO^–) formed by 3-morpholinosydnonimine. In particular, 12 compounds showed potent activity, with IC₅₀ values in the range 0.14–2.2 μM

A new secoiridoid glycoside from the fruits of <i>Cornus officinalis</i> (Cornaceae)

<p>A new secoiridoid glycoside, 7β-<i>O</i>-dimethyl butanedioate morroniside (<b>1</b>) was isolated from the fruits of <i>Cornus officinalis</i> (Cornaceae) along with the known compound, caffeoyltartaric acid dimethyl ester (<b>2</b>) which was isolated from the family Cornaceae for the first time. Their structures were elucidated by physical and spectroscopic data analysis, including 1D and 2D NMR, ESI-MS and CD experiments.</p