2 research outputs found
Common Aeroallergens in Patients with Asthma and Allergic Rhinitis Living in Southwestern Part of Iran: Based on Skin Prick Test Reactivity
Aeroallergens continue to have a key role in the pathogenesis of asthma and allergic diseases and have recently received increased attention in medical research throughout the world. The prevalence of aeroallergens vary in different regions, depending on the type of climate. The aim of the present study was to determine prevalence of the sensitivity to aeroallergens among patients with asthma and allergic rhinitis (AR), based on skin prick test (SPT) reactivity in the province of Bushehr, Iran.
In this cross-sectional study, 743 patients were enrolled. The participants had asthma and AR and reacted to at least one allergen with SPT. Skin prick test with standard extracts including house dust mites (HDMs), animal dander, molds and pollens were performed on patients according to the herbal geography of the area.
The male to female ratio and mean age of the patients were 1.03 and 27.6± 15.4 year, respectively. Out of 567 patients with AR, the common aeroallergens were HDMs (88.5%), molds (82.9%), animal dander (79.5%), weeds (77.6%), trees (75.5%) and grass pollen (71.5%). Moreover, among 176 patients with asthma, the prevalence of aeroallergens were HDMs (90.5 %), molds (80.7%), animal dander (77.5%), weeds (73.3%), trees (73.3%) and grass pollen (67.9%). The sensitivity to animal dander, Chenopodium album and Russian thistle pollens were significantly associated with the severity of AR. Moreover, sensitivity to animal dander such as cat and feather of birds, cockroach, Bermuda grass and Chenopodium album pollens were significantly associated with the severity of asthma.
The results of this study revealed that HDM was the most common sensitizing aeroallergen in patients with asthma and AR. Molds and animal dander as indoor allergens were also common aeroallergens. We suggest that the hot weather and ambient humidity in the region may be the main cause of the change in the pattern of SPT reactivity
Prevalence and Risk Factors of Asthma and Allergic Diseases in Primary Schoolchildren Living in Bushehr, Iran: Phase I, III ISAAC Protocol
Asthma and allergic diseases present a major health burden. Information on the
prevalence of these diseases indicates that these diseases are increasing in various parts of the
world. It was hoped that this study would be helpful to health system policy-makers in
planning allergy prevention programs in the region.
The prevalence of asthma and allergic diseases and relation between the various risk
factors involved were assessed among schoolchildren in the city of Bushehr, Iran. The
ISAAC Phase I and III questionnaires were completed by parents of 1280 children aged 6-7
years and self-completed by 1115 students aged 13-14 years.
The prevalence of atopic eczema, allergic rhinitis and asthma among 6-7 year-old students
were 12.1%, 11.8% and 6.7%, respectively. While, the prevalence of these diseases among
13-14 year-old students were found to be 19%, 30% and 7.6%, respectively. There was an
association between asthma and allergic rhinitis as well as eczema (p<0.05). Consumption of
fast food as a risk factor was significantly associated with asthma (p=0.03).
The prevalence of asthma and allergic diseases was high among schoolchildren in the city
of Bushehr, Iran. Also an association was observed between the fast food consumption and
asthma.
Keywords: Allergic rhinitis; Asthma, Atopic eczema; Children; ISAAC; Prevalenc