A statistical mechanics description of environmental variability in metabolic networks

Many of the chemical reactions that take place within a living cell are irreversible. Due to evolutionary pressures, the number of allowable reactions within these systems are highly constrained and thus the resulting metabolic networks display considerable asymmetry. In this paper, we explore possible evolutionary factors pertaining to the reduced symmetry observed in these networks, and demonstrate the important role environmental variability plays in shaping their structural organization. Interpreting the returnability index as an equilibrium constant for a reaction network in equilibrium with a hypothetical reference system, enables us to quantify the extent to which a metabolic network is in disequilibrium. Further, by introducing a new directed centrality measure via an extension of the subgraph centrality metric to directed networks, we are able to characterise individual metabolites by their participation within metabolic pathways. To demonstrate these ideas, we study 116 metabolic networks of bacteria. In particular, we find that the equilibrium constant for the metabolic networks decreases significantly in-line with variability in bacterial habitats, supporting the view that environmental variability promotes disequilibrium within these biochemical reaction system

Heavy Quark Fluorescence

Heavy hadrons containing heavy quarks (for example, Upsilon-mesons) feature a scale separation between the heavy quark mass (about 4.5 GeV for the b-quark) and the QCD scale (about 0.3 GeV}) that controls effective masses of lighter constituents. Therefore, as in ordinary molecules, the de-excitation of the lighter, faster degrees of freedom leaves the velocity distribution of the heavy quarks unchanged, populating the available decay channels in qualitatively predictable ways. Automatically an application of the Franck-Condon principle of molecular physics explains several puzzling results of Upsilon(5S) decays as measured by the Belle collaboration, such as the high rate of Bs*-anti Bs* versus Bs*-anti Bs production, the strength of three-body B-anti B + pion decays, or the dip in B momentum shown in these decays. We argue that the data is showing the first Sturm-Liouville zero of the Upsilon(5S) quantum mechanical squared wavefunction, and providing evidence for a largely b-anti b composition of this meson.Comment: 4 pages, 4 figures, Figure 2 updated and some typos corrected. To be published in Physical Review Letter

On the determination of Θ+\Theta^+ quantum numbers and other topics of exotic baryons

In this talk I look into three different topics, addressing first a method to determine the quantum numbers of the $\Theta^+$, then exploiting the possibility that the $\Theta^+$ is a bound state of $K \pi N$ and in the third place I present results on a new resonant exotic baryonic state which appears as dynamically generated by the Weinberg Tomozawa $\Delta K$ interaction.Comment: 9 pags. Talk in the NSTAR04 Workshop, Grenoble, march 200

Hadronic aspects of exotic baryons

In this talk I look into three different topics, addressing first the possibility that the $\Theta^+$ is a bound state of $K \pi N$, exploiting the results of this study to find out the contribution of two meson and one baryon components in the baryon antidecuplet and in the third place I present results on a new resonant exotic baryonic state which appears as dynamically generated by the Weinberg Tomozawa $\Delta K$ interaction.Comment: Talk at the International Workshop PENTAQUARK0

Thermal Risk Mitigation Testing of the DarkNESS Observatory for Fermi NationalAccelerator Laboratory

This paper presents the prototype design and laboratory test results of the thermal control system for the Dark matter as sterile Neutrino Search Satellite (DarkNESS). A collaboration between Fermilab, CU Aerospace, and the University of Illinois Department of Aerospace Engineering’s Laboratory for Advanced Space Systems (LASSI), the 6U satellite uses a Skipper CCD to detect weak 3.55 – 3.57 keV X-ray emissions, previously discovered by the XMM-Newton and Chandra X-ray observatories. To minimize read-out noise, the thermal control system incorporates a 10 W integral rotary cryocooler and passive heat transfer elements, maintaining the CCD at an operating temperature of 170 K. Analyses of the Earth\u27s obstruction of the instrument’s field of view and the impact of external heating on the instrument aperture established performance requirements and attitude constraints for the thermal control system. A high-fidelity test of a preliminary design was performed in a thermal vacuum chamber, prompting modifications to improve the thermal system design margins. This effort precedes the Critical Design Review milestone

"Clumpiness" Mixing in Complex Networks

Three measures of clumpiness of complex networks are introduced. The measures quantify how most central nodes of a network are clumped together. The assortativity coefficient defined in a previous study measures a similar characteristic, but accounts only for the clumpiness of the central nodes that are directly connected to each other. The clumpiness coefficient defined in the present paper also takes into account the cases where central nodes are separated by a few links. The definition is based on the node degrees and the distances between pairs of nodes. The clumpiness coefficient together with the assortativity coefficient can define four classes of network. Numerical calculations demonstrate that the classification scheme successfully categorizes 30 real-world networks into the four classes: clumped assortative, clumped disassortative, loose assortative and loose disassortative networks. The clumpiness coefficient also differentiates the Erdos-Renyi model from the Barabasi-Albert model, which the assortativity coefficient could not differentiate. In addition, the bounds of the clumpiness coefficient as well as the relationships between the three measures of clumpiness are discussed.Comment: 47 pages, 11 figure

Croup and COVID‐19

info:eu-repo/semantics/publishedVersio

"Clumpiness" Mixing in Complex Networks

Three measures of clumpiness of complex networks are introduced. The measures quantify how most central nodes of a network are clumped together. The assortativity coefficient defined in a previous study measures a similar characteristic, but accounts only for the clumpiness of the central nodes that are directly connected to each other. The clumpiness coefficient defined in the present paper also takes into account the cases where central nodes are separated by a few links. The definition is based on the node degrees and the distances between pairs of nodes. The clumpiness coefficient together with the assortativity coefficient can define four classes of network. Numerical calculations demonstrate that the classification scheme successfully categorizes 30 real-world networks into the four classes: clumped assortative, clumped disassortative, loose assortative and loose disassortative networks. The clumpiness coefficient also differentiates the Erdos-Renyi model from the Barabasi-Albert model, which the assortativity coefficient could not differentiate. In addition, the bounds of the clumpiness coefficient as well as the relationships between the three measures of clumpiness are discussed.Comment: 47 pages, 11 figure

Twisted Covariant Noncommutative Self-dual Gravity

A twisted covariant formulation of noncommutative self-dual gravity is presented. The formulation for constructing twisted noncommutative Yang-Mills theories is used. It is shown that the noncommutative torsion is solved at any order of the $\theta$-expansion in terms of the tetrad and some extra fields of the theory. In the process the first order expansion in $\theta$ for the Pleba\'nski action is explicitly obtained.Comment: 23+1 pages, no figures, corrected typos, references and Appendix B is adde

Electromagnetic semitransparent δ\delta-function plate: Casimir interaction energy between parallel infinitesimally thin plates

We derive boundary conditions for electromagnetic fields on a $\delta$-function plate. The optical properties of such a plate are shown to necessarily be anisotropic in that they only depend on the transverse properties of the plate. We unambiguously obtain the boundary conditions for a perfectly conducting $\delta$-function plate in the limit of infinite dielectric response. We show that a material does not "optically vanish" in the thin-plate limit. The thin-plate limit of a plasma slab of thickness $d$ with plasma frequency $\omega_p^2=\zeta_p/d$ reduces to a $\delta$-function plate for frequencies ($\omega=i\zeta$) satisfying $\zeta d \ll \sqrt{\zeta_p d} \ll 1$. We show that the Casimir interaction energy between two parallel perfectly conducting $\delta$-function plates is the same as that for parallel perfectly conducting slabs. Similarly, we show that the interaction energy between an atom and a perfect electrically conducting $\delta$-function plate is the usual Casimir-Polder energy, which is verified by considering the thin-plate limit of dielectric slabs. The "thick" and "thin" boundary conditions considered by Bordag are found to be identical in the sense that they lead to the same electromagnetic fields.Comment: 21 pages, 7 figures, references adde