5 research outputs found
Restrictive IgG antibody response against mutated citrullinated vimentin predicts response to rituximab in patients with rheumatoid arthritis
Restrictive IgG antibody response against mutated citrullinated vimentin predicts response to rituximab in patients with rheumatoid arthritis
Additional file 3: Figure S1. of Restrictive IgG antibody response against mutated citrullinated vimentin predicts response to rituximab in patients with rheumatoid arthritis
ROC curve analysis for AMCV IgA assay. Cut-off level at 20 U/ml resulted in a specificity of 100 % and sensitivity of 42 %. (DOCX 23 kb
Additional file 2: Table S2. of Restrictive IgG antibody response against mutated citrullinated vimentin predicts response to rituximab in patients with rheumatoid arthritis
Sequence of selected mutated citrullinated vimentin (MCV) with epitopes from 1 to 88. The entire protein sequence of MCV was cut into 88 peptides consisting of 17 amino acids, with 12 overlapping amino acids to the neighbourhood peptide, with following amino acid code: X = citrulline; X = mutated glycine = citrulline; H = mutated serine = histidine. (DOCX 18 kb