2,495 research outputs found
Scraping the Social? Issues in live social research
What makes scraping methodologically interesting for social and cultural research? This paper seeks to contribute to debates about digital social research by exploring how a ‘medium-specific’ technique for online data capture may be rendered analytically productive for social research. As a device that is currently being imported into social research, scraping has the capacity to re-structure social research, and this in at least two ways. Firstly, as a technique that is not native to social research, scraping risks to introduce ‘alien’ methodological assumptions into social research (such as an pre-occupation with freshness). Secondly, to scrape is to risk importing into our inquiry categories that are prevalent in the social practices enabled by the media: scraping makes available already formatted data for social research. Scraped data, and online social data more generally, tend to come with ‘external’ analytics already built-in. This circumstance is often approached as a ‘problem’ with online data capture, but we propose it may be turned into virtue, insofar as data formats that have currency in the areas under scrutiny may serve as a source of social data themselves. Scraping, we propose, makes it possible to render traffic between the object and process of social research analytically productive. It enables a form of ‘real-time’ social research, in which the formats and life cycles of online data may lend structure to the analytic objects and findings of social research. By way of a conclusion, we demonstrate this point in an exercise of online issue profiling, and more particularly, by relying on Twitter to profile the issue of ‘austerity’. Here we distinguish between two forms of real-time research, those dedicated to monitoring live content (which terms are current?) and those concerned with analysing the liveliness of issues (which topics are happening?)
Redshift clustering in the Hubble Deep Field
We present initial results from a redshift survey carried out with the Low
Resolution Imaging Spectrograph on the 10~m W. M. Keck Telescope in the Hubble
Deep Field. In the redshift distribution of the 140 extragalactic objects in
this sample we find 6 strong peaks, with velocity dispersions of
{\kms}. The areal density of objects within a particular peak, while
it may be non-uniform, does not show evidence for strong central concentration.
These peaks have characteristics (velocity dispersions, density enhancements,
spacing, and spatial extent) similar to those seen in a comparable redshift
survey in a different high galactic latitude field (Cohen et al 1996),
confirming that the structures are generic. They are probably the high redshift
counterparts of huge galaxy structures (``walls'') observed locally.Comment: 14 pages, including 2 figures, to appear in ApJ Letter
Potential risk of Artemia sp as a transmission vector of lymphocystis disease virus (LCDV)
4 páginas, 1 figura. XI Congreso Nacional de Acuicultura (Vigo, 24-28 septiembre 2007). Ed. Antonio Cerviño Eiroa, Alejandro Guerra Díaz y Carmen Pérez Acosta.[EN] Cysts and naupliis of Artemia sp. were analysed. Specific nested-PCR revealed lymphocystis disease virus (LCDV) genome. Infective viral particle has been observed by CPE development in inoculated cell cultures. Viral genome was found by in situ hybridization in nauplii and adults of natural infected artemia, as in nauplii of bath challenged artemia. No morphological damages have been observed.
Artemia is a bio-accumulator of fish pathogens, with a possible role as environmental reservoir of fish pathogens. These results have shown the risk of artemia as a source of viral pathogens to fish larvae.[ES] En el presente trabajo se han realizado estudios virológicos en distintos lotes de quistes comerciales de artemias utilizados como alimento de larvas de peces marinos en piscifactorías. Mediante nested-PCR se ha detectado genoma del virus de linfocistis (LCDV) en homogeneizados de quistes y nauplios de artemia. La existencia de partículas víricas infectivas en estos
homogeneizados se ha demostrado mediante la aparición de efectos citopáticos en cultivos
celulares. Los ensayos de hibridación in situ han demostrado la existencia del LCDV en artemias infectadas naturalmente, así como en artemias inoculadas mediante baño, sin observarse alteraciones morfológicas.
Las artemias actúan por tanto como bioacumuladores, pudiendo desempeñar un papel importante como reservorios ambientales de patógenos de peces. Estos resultados ponen de manifiesto el riesgo potencial de las artemias como fuente de patógenos víricos en estadios larvarios.Irene Cano es contratada postdoctoral en el ICMAN.CSIC dentro del Fondo social europeo- I3P-CSIC, en el marco del proyecto AGL2006-17777-C03-02/ACU (IP: Carmen Sarasquete).Peer reviewe
Data on microhardness and structural analysis of friction stir spot welded lap joints of AA5083-H116
Friction stir spot welding (FSSW) was established to compete reasonably with the reverting, bolting, adhesive bonding as well as resistance spot welding (RSW) which have been used in the past for lap joining in automobile, aerospace, marine, railways, defence and shipbuilding industries. The use of these ancient and conventional joining techniques had led to increasing material cost, installation labour, and additional weight in the aircraft, shipbuilding, and other areas of applications. All these are disadvantages that can be overcome using FSSW. This research work carried out friction stir spot welding on 5058-H116 aluminium alloy by employing rotational speed in the step of 300 rpm ranges from 600 rpm to 1200 rpm with a no travel speed. It was noted that the dwell times were in the step of 5 s varying from 5 s to 15 s while the tool plunge rate was maintained at 30 mm/min. In this dataset, a cylindrical tapered rotating H13 Hot-working steel tool was used with a probe length of 5 mm and probe diameter of 6 mm, it has a shoulder diameter of 18 mm. The tool penetration depth (plunge) was maintained at 0.2 mm and the tool tilt angle at 2°. Structural integrity was car-ried out using Rigaku ultima IV multifunctional X-ray diffractometer (XRD) with a scan voltage of 40 kV and scan current of 30 mA. This was used to determine crystallite sizes, peak intensity, d-spacing, full width at half maximum intensity (FWHM) of the diffraction peak. TH713 digital microhardness equipment with diamond indenter was used for microhardness data acquisition following ASTM E92–82 standard test. The average Vickers hardness data values at different zones of the spot-welds were captured and presented
Data on microhardness and structural analysis of friction stir spot welded lap joints of AA5083-H116
Friction stir spot welding (FSSW) was established to compete reasonably with the reverting, bolting, adhesive bonding as well as resistance spot welding (RSW) which have been used in the past for lap joining in automobile, aerospace, marine, railways, defence and shipbuilding industries. The use of these ancient and conventional joining techniques had led to increasing material cost, installation labour, and additional weight in the aircraft, shipbuilding, and other areas of applications. All these are disadvantages that can be overcome using FSSW. This research work carried out friction stir spot welding on 5058-H116 aluminium alloy by employing rotational speed in the step of 300 rpm ranges from 600 rpm to 1200 rpm with a no travel speed. It was noted that the dwell times were in the step of 5 s varying from 5 s to 15 s while the tool plunge rate was maintained at 30 mm/min. In this dataset, a cylindrical tapered rotating H13 Hot-working steel tool was used with a probe length of 5 mm and probe diameter of 6 mm, it has a shoulder diameter of 18 mm. The tool penetration depth (plunge) was maintained at 0.2 mm and the tool tilt angle at 2°. Structural integrity was car-ried out using Rigaku ultima IV multifunctional X-ray diffractometer (XRD) with a scan voltage of 40 kV and scan current of 30 mA. This was used to determine crystallite sizes, peak intensity, d-spacing, full width at half maximum intensity (FWHM) of the diffraction peak. TH713 digital microhardness equipment with diamond indenter was used for microhardness data acquisition following ASTM E92–82 standard test. The average Vickers hardness data values at different zones of the spot-welds were captured and presented
Who do we inform? The role of status and target in intergroup whistle-blowing
In two experiments (n = 87 and n = 90), we showed that strongly identifying members of a low status group are more likely to actively inform the ingroup rather than the outgroup about an outgroup transgression, and consider it as more loyal to the ingroup to do so. Moreover, strongly identifying members of a high status group are more likely to actively inform the outgroup rather than the ingroup about an outgroup transgression, and consider this to be more loyal to the ingroup. The results are in support of the notion that, depending on a group's existing status position, negative outgroup information can be used to enhance or confirm the ingroup's standing, affecting whether the ingroup or the outgroup will initially be informed about an outgroup transgression. Copyright © The Author(s), 2009
Hyperferritinemia without iron overload in patients with bilateral cataracts: a case series
Hepatologists and internists often encounter patients with unexplained high serum ferritin concentration. After exclusion of hereditary hemochromatosis and hemosiderosis, rare disorders like hereditary hyperferritinemia cataract syndrome should be considered in the differential diagnosis. This autosomal dominant syndrome, that typically presents with juvenile bilateral cataracts, was first described in 1995 and has an increasing number of recognized molecular defects within a regulatory region of the L-ferritin gene (FTL).
CASE PRESENTATION: Two patients (32 and 49-year-old Caucasian men) from our ambulatory clinic were suspected as having this syndrome and a genetic analysis was performed. In both patients, sequencing of the FTL 5' region showed previously described mutations within the iron responsive element (FTL c.33 C > A and FTL c.32G > C).
CONCLUSION: Hereditary hyperferritinemia cataract syndrome should be considered in all patients with unexplained hyperferritinemia without signs of iron overload, particularly those with juvenile bilateral cataracts. Liver biopsy and phlebotomy should be avoided in this disorder
Prophylactic properties of a Leishmania-specific hypothetical protein in a murine model of visceral leishmaniasis
In this work, the effect of vaccination of a newly described Leishmania infantum antigenic protein has been studied in BALB/c mice infected with this parasite species. The LiHyD protein was characterized after a proteomic screening performed with the sera from dogs suffering visceral leishmaniasis (VL). Its recombinant version was expressed, purified and administered to BALB/c mice in combination with saponin. As a result of vaccination and 10 weeks after challenge using an infective dose of L. infantum stationary promastigotes, vaccinated mice showed lower parasite burdens in different organs (liver, spleen, bone marrow and footpads' draining lymph nodes) than mice inoculated with the adjuvant alone or the vaccine diluent. Protected mice showed anti-Leishmania IgG2a antibodies and a predominant IL-12-driven IFN-γ production (mainly produced by CD4 T cells) against parasite proteins, whereas unprotected controls showed anti-Leishmania IgG1 antibodies and parasite-mediated IL-4 and IL-10 responses. Vaccinated mice showed an anti-LiHyD IgG2a humoral response, and their spleen cells were able to secrete LiHyD-specific IFN-γ, IL-12 and GM-CSF cytokines before and after infection. The protection was correlated with the Leishmania-specific production on nitric oxide. Altogether, the results indicate that the new LiHyD protein could be considered in vaccine formulations against VL.Instituto Nacional de Ci^encia e Tecnologia em Nano-biofarmac^eutica (INCT-NanoBiofar), FAPEMIG (CBB-APQ-00819-12 and CBB-APQ-01778-2014) and CNPq (APQ-482976/2012-8, APQ-488237/2013-0 and APQ-467640/2014-9). In addition, this study was partially funded by the Spanish grant from Ministerio de Economía y Competitividad-FEDER (FIS PI14/00366 from the Instituto de Salud Carlos III)Peer Reviewe
Using online adverts to increase the uptake of cervical screening amongst "real Eastenders": an opportunistic controlled trial.
BACKGROUND: Cervical screening uptake has increased as a result of occurrences of cervical cancer in TV 'soap operas' and in real life celebrities such as Jade Goody. Media analysis at the time of Jade Goody's death suggested the NHS did not take sufficient advantage of this opportunity to improve cervical screening rates. Google AdWords has been used to recruit and raise awareness of health but we were not aware of its use to supplement media events. METHODS: This was an opportunistic service evaluation to accompany a cervical cancer storyline in Eastenders (a TV 'soap opera'). We ran an AdWords campaign based on keywords such as 'Eastenders', and 'cervical cancer' in a one mile radius in East London, linked to one webpage giving details of 10 practices and other links on cervical cancer. We recorded costs of adverts and setting up the webpage. We used routine statistics from Tower Hamlets, City and Hackney, and Newham Primary Care Trusts (PCTs) of the number of smears, eligible populations, and coverage by practice by month from September 2010 to January 2012 to compare the ten intervention practices with controls. RESULTS: Eight people per day in the target area viewed the project webpage. The cost of setting up the website and running Google AdWords was £1320 or £1.88 per person viewing the webpage. Unlike Jade Goody's death, there was no major impact from the Eastenders' storyline on Google searches for cervical cancer. There was considerable monthly variation in the number of smear tests in the 3 PCTs. The AdWords campaign may have had some effect on smear rates but this showed, at best, a marginal statistical difference. Assuming a 'real' effect, the intervention may have resulted in 110 'extra' women being screened but there was no change in coverage. CONCLUSIONS: Although the Eastenders storyline seemed to have no effect on interest in cervical cancer or screening, the AdWords campaign may have had some effect. Given the small scale exploratory nature of the study this was not statistically significant but the relatively modest cost of advertising suggests a larger study may be worthwhile. An outline of a possible study is described
- …