11 research outputs found

    Facteurs de risque de mortalité chez les patients tuberculeux surinfectés par le VIH à Douala (Cameroun).

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    Despite prevention efforts, and free treatment, TB-HIV co-infection still occurs in Cameroon. The objective of this work is to present the risk factors for mortality in patients co-infected with TB and HIV in Douala from 2009 to 2014. This transversal, analytic, and retrospective study took place from November 2014 to May 2015 in the Laquintinie Hospital in Douala. A review of our records identified patients aged at least 15 years, with this co-infection who received TB treatment, with or without antiretroviral agents. The bivariate analysis compared qualitative variables with Pearson's Chi2 test. In the multivariate analysis, we determined the risk factors for mortality by backward stepwise logistic regression. Model fit was tested with the Hosmer-Lemeshow test. The study identified 394 patients, 213 (54.1%) of whom were women (sex ratio 0.84). The mean age was 39 ± 10 years. All patients received drugs to treat tuberculosis drugs; 351 (89%) also received antiretroviral drugs, 78.2% of them including efavirenz; and 320 (81.2%) received cotrimoxazole prophylaxis. During the study period, 67.3% were cured of tuberculosis and 15.7% died. The multivariate regression results show that hepatitis B (P <0.0009), absence of cotrimoxazole prophylaxis (P <0.005), poor treatment adherence (P <0.0001), and a CD4 count <50 (P <0.0001) were risk factors for mortality. The cure rate for patients co-infected with TB and HIV in Cameroon remains low, and their mortality high. Comorbidities and the presence of opportunistic diseases are risk factors for death. Appropriate measures to prevent this co-infection and the systematic use of cotrimoxazole should reduce this mortality rate.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

    Otogenic tetanus in a 6 years old girl: A case report in Cameroon

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    Tetanus is a severe infectious disease due to Clostridium tetani. It is preventable by immunization. Otogenic tetanus is a rare presentation of this disease. It is a severe complication of otitis media in Children. It is related to high mortality especially in low-income countries due to lack of complete immunization and unawareness of caregivers. We report a case of otogenic tetanus in a 6 years old girl who presented with right ear discharge and dysphagia &nbsp; English title: Tétanos otogène chez une fille de 6 ans : A propos d’un cas au Cameroun&nbsp; Le tétanos est une maladie infectieuse due au Clostridium tetani. Elle est évitable par la vaccination. Le tétanos otogène est une forme rare de la maladie. C’est une complication grave de l’otite moyenne aigue chez l’enfant. Souvent méconnue, elle est à l’origine d’une mortalité élevée dans les pays à ressources limitées. Par ailleurs, le statut vaccinal incomplet ou l’absence de vaccination contre le tétanos constituent un terrain favorable à cette complication. Nous rapportons un cas de tétanos otogène chez un enfant de 6 ans qui présentait une otorrhée droite et une dysphagie à l’admission

    Use of oral rehydration therapy in the treatment of childhood diarrhoea in Douala, Cameroon.

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    The use of oral rehydration solutions in our context remains limited. This study was conducted to analyze the rate of this use in Douala, Cameroon and thereby determine the factors associated with it.info:eu-repo/semantics/publishe

    Seroprevalence, attitudes and practices of the Baka Pygmies of eastern Cameroon towards HIV and AIDS.

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    The vulnerable health status of Pygmies is the result of their continual exposure to the modern world. The purpose of this study was to determine the prevalence of HIV and the attitudes and practices of Baka populations towards HIV infection.info:eu-repo/semantics/publishe
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