Treatment of experimental Toxocara cati infection in mice with ivermectin and moxidectin

The aim of this study was to investigate the efficacy of two efficient macrocyclic lactone drugs, ivermectin, and moxidectin, on the numbers and distribution of Toxocara cati larvae in experimentally infected mice. Different post-infection periods (48 h and 7 d) and different administration methods (oral and subcutaneous) were compared. lvermectin and moxidectin were tested (0.2 mg/kg with a single dose) for their larvicidal effects. Each mouse was infected with 1 000-embryonated eggs of T cati. On the 10 d of the infection, the mice in each treatment group and the control group were sacrificed and the presence of T cati larvae in various organs were determined and compared between groups. Statistically, the treatment regimens in all treatment groups were successful as compared with the controls. The worst results were achieved in the group in which ivermectin was given orally 7 d following egg inoculation. According to the decrease in total larvae recovery, oral administration of moxidectin 48 h following egg inoculation displayed the highest efficacy. The effect of ivermectin administered subcutaneously 7 d following infection was more effective than subcutaneous application of moxidectin after both 48 h and 7 d

A Coprological Study of Helminth Infections of Horses in Istanbul, Turkey

A coprological study to determine the helminth infections of horses in Istanbul was carried out. Individual fecal samples were taken from 204 horses (111 males and 93 females) of varying ages and breeds. The samples were examined for eggs by Fulleborn's flotation, Benedect's sedimentation methods and for the larvae of lungworm by the Baermann's method. Further individual larval cultures were performed from fecal samples for the identification of 3rd stage larvae (L3) of strongyle nematodes. It was found that 33(16.2%) of 204 horses were infected with any nematode species, 23(11.3%) with Cyathostomin nematodes, 17(8.3%) with cyathostomins except Gyalocephalus and Posteriostomum, 13 (6.4%) with Poteriostomum spp., 11(5.4%) with Strongylus edentatus, 7 (3.4%) with Trichostrongylus axei, 4 (2.0%) with Triodontophorus spp., 3 (1.5%) with Strongyloides westeri, 1 (0.5%) with Gyalocephalus capitatus, 1 (0.5%) with Oxyuris equi, 1 (0.5%) with Parascaris equorum, and 1 (0.5%) with Oesophagodontus robustus. Out of 204 horses, 15 (7.4%) were infected with only one species, 12 (5.9 %) with two species, 4 (1.9%) with three species, and 2 (0.9%) with four species. No trematode or cestode eggs could be detected

Two Chewing Lice Species, Colpocephalum subzerafae and Laemobothrion tinnunculi, on A Kestrel (Falco tinnunculus) in Istanbul: Two New Records from Turkey

On the examination of a male kestrel (Falco tinnunculus), which was captured in Istanbul in June of 2011, three lice were collected. The lice were examined microscopically and two species of chewing lice (Colpocephalum subzerafae and Laemobothrion tinnunculi) were identified. All of the lice were male. These species are recorded for the first time from Turkey