Hereditary Angioedema Type II: First Presentation in Adulthood with Recurrent Severe Abdominal Pain

A 27-year-old Emirate man presented to Cleveland Clinic Abu Dhabi emergency department with a 4 year history of recurrent episodes of severe swellings affecting different parts of his body. He used to get 2 swelling episodes every week affecting either his face, hands, feet or scrotum and severe abdominal pain twice a week. Abdominal CT scan and a colonoscopy showed bowel wall oedema. There was no family history of similar complaint or of hereditary angioedema (HAE). Complement studies confirmed the diagnosis of HAE type II. He was commenced on danazol 100 mg twice daily and his symptoms resolved. This case report highlights the importance of considering HAE in patients with recurrent unexplained abdominal pain even in the absence of positive family history of HAE

CORONARYARTERY CALCIFICATION IN PATIENTS UNDERGOING RENALREPLACEMENT THERAPIES

Objective: Cardiovascular disease (CVD) is a common cause of morbidity and mortality both in patients undergoing dialysis and in transplant recipients. The presence of calcified coronary lesions, as can be determined and quantified by electron-beam computed tomography (EBCT), is closely correlated with the extent and severity of angiographically documented atherosclerotic lesions. In the present study, coronary artery calcifications (CAC) were measured and compared in hemodialysis (HD) patients and in transplant recipients and their correlation with other patient characteristics was assesed